Lots more in the paper (#cryoEM etc!)
https://t.co/IrVR3JkLJY
Big thanks to coauthors @_David_Li@algao8 Rhiannon Macrae and @zhangf
Please also check out @shsternberg@stephentang23 related work - we come up with similar models, but it'll be exciting to resolve the differences!
EMBO Gold Medal awarded to Elvan Böke @LabBoke to recognize her pioneering research on physiological mechanisms that enable oocytes to stay healthy over decades of dormancy @CRGenomica
https://t.co/bO8c42rNiB
Julia Mahamid @EMBL & Eva Nogales @UCBerkeley discuss "...how different combinations of electron microscopy methods...can bring us closer to our ultimate dream of understanding how macromolecules operate inside our cells...".
Read the review 👇
https://t.co/kaW1Tsq5wX
Beyond excited to share my first paper from my PhD @DPhaz Lab @IMS_MRL now out in @embojournal! Special thanks to Sam from @TVPLab and @dougall_norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:
https://t.co/mG8PFGudGT
High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria https://t.co/YZZ2njfWd4
Check out my lab's first work on membrane proteins!
Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!
We are excited to share our latest insights into human mRNA export. Pre-print: https://t.co/TCO75EW1f3; tweetorials below and https://t.co/824pXYIDgl by the exceptional @HohmannUlrich, who led the project in a joint effort of the @plaschka_lab and @JuliusBrennecke labs. (1/7)
The U5 snRNP makes up the “heart” of the human spliceosome, which is made and recycled by two chaperones, CD2BP2 and TSSC4. But how is this done? See our latest work to find out, co-lead by the great @DarRiabov and Pat Visanpattanasin. https://t.co/5ZGTpRsevt (1/5)
U5 snRNP is one of the key building blocks of the spliceosome, but how it is assembled and recycled remains unknown.
Check out our latest paper to find out more about this process:
https://t.co/KmjkCR3JeZ
#RNP#splicing#cryoEM@EMBLGrenoble@ERC_Research
💫NEW: @MartinWuhr, @brangwynnelab & co use filtration chromatography & quantitative #proteomics of Xenopus egg extracts and show that at least 18% of cytoplasmic proteins are organized in small ~100-nm #BiomolecularCondensates.
👉https://t.co/bAHp8DwHuW
https://t.co/C6r6rpoTlH
Excited to present our latest research @Nature where we unveil the mystery of UFMylation, a crucial process for protein homeostasis at the ER https://t.co/3X29st4Lg7
1/ 📢New #paper alert! Ever wondered how mammalian #oocytes deal with protein #aggregation during their prolonged #life? Check it out in our new paper led by @zaffagg3 out today in @CellCellPress: https://t.co/mH7Hcb41is
👇🏽a thread:
Very excited to share our paper out today in @naturemethods, introducing TREX (Targeted RNase H-mediated Extraction of X-linked RBPs), a novel approach to reveal proteins that bind to any region of any RNA molecule of interest in living cells🧪: https://t.co/rVU8X9W0ED (1/10)