Laboratory of organelle biogenesis and homeostasis - studying ER organization and size control; discovering roles for the nuclear envelope lipid environment
Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7)
https://t.co/SbshGhofN0
James Olzmann (@OlzmannLab at @UCBerkeley) won the 2026 Avanti Award in Lipids. His work has advanced knowledge of lipid droplets, lipid metabolism & ferroptosis.
⏯️Watch his #ASBMB26 talk, "Guardians of the membrane": https://t.co/6udu44rgH6
#LipidResearch@AvantiResearch
Pleased to share our review on chromosomal instability (CIN) and aneuploidy in cancer, led by @AmandaMennie. Now out @AnnualReviews!
https://t.co/WX35326zmp
Visibility in Academia, like in the world, is not fixed; it is produced. This piece “What Cell Biology Reveals About Academia” is a reminder that everyone has the potential to be either seen or unseen.
https://t.co/qKHzGx6oec
Happy to share this collaborative work published in @Nature today: “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly” by @OlzmannLab@apsarruda , led by co–first authors @alymathiowetz and @EmilyMeymand
https://t.co/SXLSCvRBqL
1/ Thrilled to share our new paper in @Nature: “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” From our lab together with @apsarruda, led by co–first authors @alymathiowetz and @EmilyMeymand. 🥳
https://t.co/LHO31rNaxi
Membrane editing with proximity labeling reveals protein networks and mechanisms regulating lipid homeostasis in the membranes of target organelles
https://t.co/kCOZ8NWfB5
Very happy to see my corresponding author paper out in MBoC (@ASCBiology). Here we explore the organisation of the yeast seipin complex across lipid droplet formation and find interesting aspects of protein recruitment and wiring to nutrient availability.
https://t.co/NtVkpM8Efv
The #ABRCMS2025 conference was my first scientific meeting as an undergrad, and it was the experience that propelled me into science. Being back this week, surrounded by brilliant, aspiring young scientists, has been incredible. #Seeingisbelieving
Ever wanted to do a genome-scale CRISPR screen for a microscopy-based phenotype? Pooled CRISPR screens are amazing, but hard to combine with microscopy... Excited to share a technology platform for such imaging screens and applications to primary cilia... https://t.co/mjxZ9flsvm
Thrilled to share our work showing that the bridge lipid transport protein ATG2A transfers diacylglycerol (DAG), and TAG/PA, from the ER to LDs, thereby recruiting DGAT2 to drive local TAG synthesis, promoting LD expansion while protecting ER membranes.
https://t.co/KFFqoBlBzn
I'm thrilled to share our new preprint, in which we've found that neurotransmitters can be chemically "marked" as a way to incorporate metabolic history - such as diet or life stage. https://t.co/l2FPY6THfV Led by Porhathai "Un" Malaiwong, Allen Schroeder and Tia Brown. 🧵(1/6)
Scientific pursuit is a team effort, built on mutual trust, respect and collaboration from mentor & mentee. Grateful every day for this journey, and so proud of my mentee @eric_jordahl for being selected as @HHMINEWS Gilliam fellow!
Humbled and honored to receive the 2026 Avanti Award in Lipids from @ASBMB! Grateful to my exceptional lab, mentors, and collaborators for their support and inspiration. Excited to keep pushing the boundaries of lipid biology and therapeutics!
https://t.co/3dGwarD2SO