@iannaconelab@CellCellPress Hi , excellent paper !!! Congrats . If posible , one question . The Td-SL cells look very much similar to canonical Tpex . Could you please develop a little bit about the differentially expressed markers than make them unique ? Many thanks and congrats again .
Big thanks to Katharine Block & Steve Jameson @Jamequistlab for this brilliant and thoughtful commentary on our recent @ImmunityCP paper. You’ve summarized it better than I could! https://t.co/zfDt8wSKws
"The maximal lifespan [of people and 347 mammalian species] is strongly associated with an epigenetic signature that is largely independent of sex, body mass, calorie restriction, or other lifestyle factors"
@ScienceAdvances
https://t.co/kk7DgGcbwr @prof_horvath and colleagues
Cellular architecture is a predeterminant of early TCR signaling and subsequent cell fate decisions of individual naïve T cells in response to antigen @ScienceMagazine@BenHalePhD@BerendSnijder
https://t.co/rtwbRnkaD9
The under-appreciated non-linear effects of transcription factors dosing on cell fate.
Fascinating work presented by @BartDeplancke at today's @ISBSIB single-cell focus group meeting.
Exciting research directions ahead.
https://t.co/qrZ9apIs6d
Happy to share an exciting work from the lab in collaboration with François Kuonen and team!
Many studies have established the impact of wounding on early steps of tumor initiation. However, little is known about the effect of wounding on progression of established human tumors.
Previously unseen details of human brain structure revealed. Featured image: a single neuron with ~5,600 of the nerve fibers that connect to it.
I feel overwhelming awe at nature's complexity and order.
https://t.co/lLiEo6z1YQ
We are thrilled that our study on PGE2-mediated impairment of TCF1+ stem-like CD8+ T cell responses in cancer, with (twitterless) Sebastian Lacher as first author, is now published @Nature! 👇 a short 🧵 below!
https://t.co/yxHgMZXS3Y
Proud to share the results of our study on the effect of prostaglandin E2 on T cells, which was just published in Nature in which we discovered a new role for PGE2 in inhibiting interleukin-2 (IL-2) sensing and signalling in tumor-reactive T cells https://t.co/9Pu6cy0JvA
Memory genes are enriched in CAR T cells that persist and control tumors in patients. But which transcription factors drive beneficial memory programs?
We answer this in our lab’s first paper in @Nature led by @alexdoan96@kpmueller1@andy_yhchen. 1/
https://t.co/qvTdqoeduz