Brigger Daniel

Scientist / Aging & Allergy Researcher

[Cell Reports @CellReports]

Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation https://t.co/n3Ogx7gdla

[Lung Precision Medicine Program @LpmDbmr]

🚨 New research alert from the Gote-SchnieringLab (@schniering_j) from our LPM cluster!🚨. Their study in JCI Insight shows that radioproteomics can non-invasively identify molecular responses to antifibrotic treatments in pulmonary fibrosis. Check out the full study here:

[Arnold_lab @lab_arnold]

OUT NOW! Your must-read #review on #eosinophils and their crucial roles in homeostasis, infection and disease. 🌋🔬 https://t.co/sFrkZFrBAt
@ArielMunitz @Arnoldwallen @NatRevImmunol #NatureReview #immunology

[aydanszeto @aydanszeto]

Thrilled to share our newest study in @ScienceMagazine. We created Boolean mice and CRISPR screened the heck outta ILC2s 🧵 1/

@MRC_LMB @wellcometrust @croucherFDN

[Immunity @ImmunityCP]

Mast cells control lung type 2 inflammation via prostaglandin E2-driven soluble ST2 https://t.co/FZhz4s3Jwd

[Jonathan Kagan @jkagan1]

A vaccine that is effective in the elderly. Pleased to share our study on the use of hyperactivator adjuvants to stimulate anti-tumor immunity in the young and old. All other vaccine adjuvants, and even checkpoint inhibitors, failed to do so.
https://t.co/xNdLgjAhgZ

[Nature Metabolism @NatMetabolism]

REVIEW | Nguyen & Corvera (@UMassDiabetes)

The authors review changes that occur in adipose tissue during #aging, discuss potential mechanisms by which these changes impact metabolism, immunity & longevity, & highlight therapeutic opportunities.

https://t.co/94HH4cjxbd

[Philipp Starkl @PhilippStarkl]

Yes, please apply if you're looking for an immunology/infectious diseases master's thesis project...it's gonna be pretty awesome 😊

[Hulda R. Jónsdóttir @HRJonsdottir]

I got to speak to @Nature about my scientific journey and my job at @SpiezLab for their Spotlight focusing on research in Switzerland.

Deadly diseases and inflatable suits: how I found my niche in virology research https://t.co/lXwXMJIMvB

[Maria Ermolaeva @MariaErmolaev13]

IgG as driver of metabolic aging? Study reports IgG accumulation in adipose tissues with age, causing macrophage-driven fibrosis and insulin resistance. Caloric restriction and blockers of IgG recycling restore metabolism by reducing IgG levels in aged WAT https://t.co/VL61Ib6937

[Stanford Knight Initiative for Brain Resilience @BrainResilience]

Knight Initiative director Tony Wyss-Coray (@wysscoray) and others are leading the development of a test measuring organ-specific proteins in the blood as a simple and sensible way to estimate biological age.
https://t.co/BMUfdwtynA

[Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM @agingdoc1]

Blood protein markers predict 15-year risk of dementia

@WeiFDU @Jianfengfenguk

https://t.co/h7WPMA10BQ | @NatureAging

[Immunity @ImmunityCP]

Online now: Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging https://t.co/23K9Tr7fIh

[Alex Eggel @AlexanderEggel]

Do you have a deep appreciation for academic and translational research? Are you eager to pursue a PhD in immunology? We are hiring! Please apply or repost.

https://t.co/Klo45lJCjo

[allen institute @AllenInstitute]

The first cellular map of a mammalian brain is here. 🧠✨

Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity.

Dive deeper: https://t.co/CXEIXooOVu

@nature #studyBRAIN #BICCN

[Oliver Hahn @Oliver__Hahn]

Thrilled to see our map of the aging mouse brain published in @CellCellPress. We find that white matter tracts are hotspots of brain aging, where (micro)glia appear to age faster. Thanks to @wysscoray and an incredible team for getting this done!
https://t.co/EcPlT4mC7A

[Dena Dubal @DenaDubal]

Platelets are a signal for klotho!!! Incredible body of work led by @park_cana. We found that longevity factor #klotho increases multiple platelet factors including PF4. PF4 permeates the brain and enhances cognition in young and old mice. @NatureAging https://t.co/sVKINPA83S

[Adam Schroer @AdamSchroer3]

Excited to share our work out now out in @Nature ! @VilledaLab @UCSFAging @SCAgingBrain
Platelet factors attenuate inflammation and rescue cognition in ageing | Nature https://t.co/aonUSjVpr7