1/3 Thrilled to see our paper led by Kirandeep Deol is out! We used CRISPR screens to uncover regulators of the ferroptosis suppressor FSP1. key discovery: vitamin B2 metabolism stabilizes FSP1 via FAD, revealing a new way vitamins regulate ferroptosis.
https://t.co/6WGXNbGRNf
How does obesity lead to immune system dysregulation and chronic inflammation?
Macrophage metabolism is rewired, with activation of the NLRP3 inflammasome @ScienceMagazine https://t.co/bkAUgOE1c2
Membrane editing with proximity labeling reveals protein networks and mechanisms regulating lipid homeostasis in the membranes of target organelles
https://t.co/kCOZ8NWfB5
The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all
the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution.
https://t.co/q3AeqGsIS1
Membrane Biology: Nothing can replace polyunsaturated lipids
Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
https://t.co/gzFL6kqazN
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—outgrowth of decades of NIH funded research
https://t.co/HmJxYWDCV7
https://t.co/4DsNELnBut @NEJM
https://t.co/y7NMGPpXnE
”I love failure.”
Medicine laureate Richard Roberts shares some of his best advice to young students and how to stay creative.
Robert participated at our recent Nobel Prize Dialogue in Tokyo, watch the full event here: https://t.co/0QTpOq12Bs
Big congrats to Raphaël Rodriguez, his lab, and the whole team of collaborators on a fantastic paper on mobilizing lysosomal iron to drive ferroptosis: https://t.co/vN2hIUcxqh
Excited to share our new study @CellReports identifying the role of atherogenic 7-ketocholesterol in Piezo1 modulation. @IPMC_sophia@CNRS
https://t.co/4yIqORWLD8
I am thrilled that our work on MemGraft probes for “permanent” fluorescent labelling of plasma membranes is out in @JACS_Au! We established a concept of lipid-directed covalent labeling of plasma membranes.
Open access: https://t.co/qKG6Jlp9rL
MemGraft probes allow cell fixation, permeabilization, trypsinization, presence of serum, long-term imaging, co-culture, cell barcoding and magnetic manipulation.
Congratulations and thanks to co-authors: @n_aknine and Rémi Pelletier.
@unistra, @CNRS, @CNRS_Alsace, @LBP_Illkirch, @AgenceRecherche
📢 Open PhD position as part of #MSCA network of 17 students
@ComeInCell
Interested in exploring membrane stability/repair & #condensates ?
Check out & apply:
👉https://t.co/5C2V9dKZQU
The project will include secondments at
@SaricLab, @MarquesLab & @NatureComms