I want to thank my parents for their encouragement and sharing their love of creativity and learning with me. I’m grateful for all the life-long friends I’ve made along the way and the memories I’ll cherish forever. (3/x)
A Mayo Clinic-led study in Cell Reports Medicine shows a new immunotherapy + hormone therapy combo could overcome a major barrier in early-stage prostate cancer treatment, offering hope for patients at high risk.
Learn more about this groundbreaking study and its potential impact: https://t.co/Awhrc2qAQG | @caseyager
PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the aforementioned M1/M2 states. M1/M2 language causes confusion and sets the field back. Refer to your macrophages by the molecules they express and the cytokines they make.
Researchers from @UCSFSurgery defined two main types of migratory dendritic cells that help maintain self-tolerance, including maternal-fetal tolerance.
Check out the 2021 research: https://t.co/Kk9V3FQbTO @gardnerlabUCSF#WeekendReads
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
We're proud to present our latest @CD_AACR study, in collaboration with @ErezNeta, unraveling the intricacies of immune cells in breast cancer metastasis & revealing that TREM2 macrophages regulate the invasive margins of metastases. >>> https://t.co/GNrL6E4m5o (1/12)
The rapid emergence of antifungal-resistant human-pathogenic fungi
Lockhart & co. discuss the global emergence & spread of Candida auris, azole-resistant Aspergillus fumigatus & Trichophyton indotineae, all three emerging with a high rate of acquired resistance.
NEW Review: The emerging family of RORγt+ antigen-presenting cells
https://t.co/0yKP5xUWnb
by Greg Sonnenberg @TheAbramsonLab@MengzeLv@HonzaDobes87
summarizes the major findings that led to their discovery and discusses discordance in recent reports
Wondering about this lovely @NatRevImmunol cover? Delve inside to find out...
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Ask @theRAD_lab and @lionakis
Fantastic to work together on this review of human pathogenic #fungi and the diseases that they cause.
https://t.co/ubxS5vmNgO
In @mbiojournal, researchers find that tolerance to the antifungal, fluconazole, is prevalent in C. albicans clinical isolates, with genetic background, temperature and drug concentration all playing a role in how tolerance (or resistance) evolves. https://t.co/yI10XoLvQA