Leandra Brettner

Postdoc, ASU Biodesign Institute, Center for Mechanisms of Evolution

[Leandra Brettner @LeandraBrettner]

@BioLayne Also, doesn’t cane sugar (sucrose) need an extra enzyme to convert to glucose and fructose whereas HFCS is just glucose and fructose as monosaccharides?

[Evan Weber @EvanWeberPhD]

An incredible feat...making a personalized, clinical-grade CRISPR gene therapy in 6 months that is actually efficacious!

As @UrnovFyodor put it, this "is a triumph for the American peoples’ investment in biomedical research"

https://t.co/ywPFaWgE0h

[Leandra Brettner @LeandraBrettner]

@johncrowd192060 Yes, of course!

[Leandra Brettner @LeandraBrettner]

My brother's niece was just diagnosed with a rare, aggressive form of brain cancer. Her parents will be living at the hospital with her for the next few months while she gets treatment. A family member set up a GoFundMe to ask for help with expenses. <3 https://t.co/NgjweD058F

[Leandra Brettner @LeandraBrettner]

@normonics @jeremykauffman Why? It’s a protein, and thus readily denatured and broken down in our acidic guts? It’s much less likely to make it though digestion than other natural insecticides like nicotine or caffeine

[Leandra Brettner @LeandraBrettner]

@jeremykauffman @normonics You also probably eat it if you eat organically produced foods as the bacteria it comes from is used as a pesticide as the whole organism for the same purpose.

[Leandra Brettner @LeandraBrettner]

@normonics @jeremykauffman BT is an insecticide, not an herbicide (it kills insects that ingest it, not plants). And it’s a protein that is highly specific to the gut of insects where it is activated by the alkaline environment.

[Leandra Brettner @LeandraBrettner]

Congrats to Rachel Eder who won first place in the undergrad category!

[Genetics Society of America @GeneticsGSA]

Congratulations to the winners of #PEQG22 GSA Poster Awards! For more details visit: https://t.co/fLgN6mRmBF

[KerryGeilerSamerotte @KSamerotte]

Congrats to @MechofEvolution members @LeandraBrettner @wchoEvo @KaraSchmidlin @SamApodaca_ and Rachel Eder on our article summarizing the challenges of studying adaptation in microbes. What a great team effort! https://t.co/dfsutC3mSh

[KerryGeilerSamerotte @KSamerotte]

Sad to miss #PEQG22 @GeneticsGSA, but happy that my lab’s undergraduates and graduate students have the opportunity to share their research! Please check out talk #5 by @SamApodaca_ & posters 212W by Rachel Eder; 382T by @dnewell_21; 306V by Natalie Quan; 316V by @gbilolikar

[Anna Kuchina @annabiosys]

Delighted to share that I’m opening a lab at Seattle’s Institute for Systems Biology @isbsci in January 2022! We will study gene expression in bacterial systems with microbial single-cell transcriptomics. We are looking for a research assistant and a postdoc!

[Leandra Brettner @LeandraBrettner]

@tamimeur @Evotec @novonordisk Good luck Leli!

[Leandra Brettner @LeandraBrettner]

@BioLayne It's also wrong. Autophagy is not renewal, it's degradation (and is often upregulated in some types of cancers). Also, there are multiple cell types that live the entire (or close) to lifespan of the organism (eg. neurons, oocytes).

[UW ECE @uw_ece]

UW ECE professor Georg Seelig’s research lab, Seelig Lab, was featured in @ScienceMagazine for its microSPLiT method for detecting gene expression states in bacteria using scRNA-seq. MicroSPLiT is a powerful tool for investigating microbial communities.

https://t.co/nj1wroWvoo

[Sloan Foundation @SloanFoundation]

Congrats to Professor @KSamerotte @ASU on being named a 2021 #sloanfellow! We are so excited to be able to support you and your work! https://t.co/ctUO3Ypedh

[Georg Seelig @seeliglab]

MicroSPLiT, our method for detecting gene expression states in bacteria using scRNA-seq, is now out at Science! @annabiosys @LeandraBrettner Luana Paleologu @RocoCharlie @dna_rosenberg @depaololab Alberto Carignano, Matthew Hirano, Ryan Kibler https://t.co/TF7fJuRYGv

[Kara Schmidlin @KaraSchmidlin]

First transfer in the books! Samples were frozen down for future sequencing work. #KGSlabEvolves @SamApodaca_ @KSamerotte

[Randolph Lopez B. @randolph380]

HT biology + ML = future of drug discovery. AlphaSeq can generate >1M of protein interaction measurements. Now, we are building the ML part of the equation. Looking for a great data scientist to join our team!

[Tileli Amimeur @tamimeur]

Our immune systems do a good job of making antibodies, but these don't always make for great drugs. We're using GANs to create humanoid antibodies, designed the way our bodies would make them, but optimized for therapeutic purposes. A new platform for faster, better drugs.

[bioRxiv @biorxivpreprint]

Designing Feature-Controlled Humanoid Antibody Discovery Libraries Using Generative Adversarial Networks https://t.co/ya4r8D9tka #bioRxiv