Mayuko Segawa

Interested in #mitochondria, #membrane biology and #biophysics

[Christie Wilcox @NerdyChristie]

They're alive!!!! ALLIIIIIIVVVEEEEEE! Newly described "zombosomes" lack a cellular 'brain' (nucleus) yet still generate energy and move about. Read about them and more of the best in @ScienceMagazine and science in this edition of #ScienceAdviser: https://t.co/A9P9lVrdOL

[Keiichi Ito @itok10918]

Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling | Nature Cell Biology https://t.co/SFw0xR7nzY

[Florent Waltz @FlorentWaltz]

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria! 
https://t.co/cxHl1j20CJ

[Martin Picard @MitoPsychoBio]

So grateful for the opportunity to chat about energy, mitochondria, and health with @hubermanlab.

Would love to hear your thoughts and lived experiences if anything resonates particularly strongly.

[Max Planck Institute of Biophysics @MPIbp]

Beautiful work on the in situ structure of ATP Synthase by @dietrich_th from the Kühlbrandt group published today in @ScienceMagazine 🔬 Discover how this important protein complex shapes the inner mitochondrial membrane! 🧪

https://t.co/xoRDR7zMgJ

[Martin Picard @MitoPsychoBio]

The brain is full of mitochondria!
But how many, and where?

Different types of mitochondria specialize for energy transformation and other functions

In MitoBrainMap v1.0 we provide the first maps of mitochondrial content and OxPhos capacity across the human brain

[Stefan Hell Labs @StefanHellLabs]

#MINFLUX detects two arrangements of a protein subunit dimer by directly resolving fluorescent markers at and below FRET-range distances. MINFLUX #imaging has gone inTRA-molecular!

Learn more at
https://t.co/oRfPLYmhrw
and
https://t.co/RXbA4DrAof

@mpinat @mpi_mr_hd #Optics #

[Alicia Kowaltowski @AJKowaltowski]

Textbook oxidative phosphorylation needs to be rewritten
with Fernando Abdulkader

https://t.co/j3LDawxKEW

Free for 50 days here: https://t.co/uEt0tOJ0Bz

[Thomas Hornall @Thomashornall]

I’m British.

I recently spent 10 days in the USA for business.

And discovered the ocean between us isn't water.

It's mindset.

7 uncomfortable truths about US v UK culture:

[PrudentLab @LabPrudent]

Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU

Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!

[Nature Reviews Molecular Cell Biology @NatRevMCB]

Now Online: Molecular mechanisms of mitochondrial dynamics https://t.co/sxHXL4XdXF

[Eric Betzig @Eric_Betzig]

#FluorescenceFriday #cellbiology #microtubules
1/3 Today, three views of microtubule (MT) growth dynamics by two different microscopes. First up, top and side views of growing MT plus ends at 1.2 volumes/sec in a HeLa cell in S phase for 150 time points, as seen by lattice light sheet microscopy https://t.co/vpdwTXqrdm

[PrudentLab @LabPrudent]

Delighted to share the last study of the lab led by the fantastic postdoc @Tabara_LC out in @CellCellPress !!!

We show how MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
@MRC_MBU @Cambridge_Uni

https://t.co/xM0vjtReOW

[MurphyLab @Mito_Redox]

Congrats to Shinpei Uno on his first paper as a postdoc working with my lab and that of Richard Hartley...first of many!

Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria‐Targeted Triphenylphosphonium Constructs https://t.co/cgzFiOru8z

[nature @Nature]

Nature research paper: Generation of functional oocytes from male mice in vitro https://t.co/Paz8Ueqkvx

[FrezzaLab @FrezzaLab]

whoa, what a day... a milestone for mitochondrial biology in cancer from the Shackelford lab! https://t.co/1c2n20X4jr

[Dylan Ryan @RyanLab_TCD]

Are you an #immunometabolism enthusiast? I'm excited to share our latest work out now in @Nature. This work was jointly led by @AlexHooftman, @ChristianGPeace & I, examining mitochondrial TCA cycle function in inflammatory macrophages 1/n
https://t.co/rUtyek95Q6

[PrudentLab @LabPrudent]

Delighted to share our last study @Nature. A wonderful collab with @FrezzaLab, led by @vincentZecchin1 and Vincent Paupe! We show that Fumarate drives mtDNA release in the cytosol via mitochondrial-derived vesicles (MDVs) to trigger innate immunity! https://t.co/L4FkuUm7KV

[Zhenqi (ZQ) Zhou @zhenqi_zhou]

Our paper is online @NatureComms "Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes". https://t.co/kbFmNXLIQJ Congrats to all authors @dgsomucla @UCLAMBI @DOM_UCLA