NK Escareño

Immunologist into cell death & NK cells @MPIbp #MembraneDynamics #Optogenetics #NLRP3 🇲🇽

[Paulo Morais @PauloMo60053925]

C1qa□ muscularis macrophages maintain enteric synaptic homeostasis to regulate gastrointestinal motility https://t.co/Wzahx2AxW6

[Leslie Vosshall PhD @leslievosshall]

📢**new pre-print article alert**
Us: OMG your entire brain is teeming with dengue virus particles
Female mosquito: [shrug][goes about daily activities]
#VosshallLab
https://t.co/MIP1QJYoUI

[オーキド博士, Ph.D. @DrOak_PhD]

同じ遺伝子をKOしたときとKDしたときと薬剤で落としたときでphenotypeが異なるのはどうして...

[Immunity @ImmunityCP]

Online now: Immunoediting restricts clonal neoantigens in primary, treatment-naive human tumors https://t.co/mwvqDv7rfV

[Greg Timblin @gtimblin]

Mitochondria acidify lysosomes through membrane contacts: Cell Reports https://t.co/OjqmPgqeHg

[Cell Reports @CellReports]

NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection https://t.co/YXmoDfrqj0

[Zak Baker @Zak_Bakes]

So excited our paper on mitochondrial phosphatidylinositol (PI) is finally out and chosen as an Editor’s Highlight in @NatureComms! PI is a known component of mitochondrial membranes, yet how its levels within mitochondria shape core functions, is unknown.
https://t.co/DdsxQYRDns

[NEJM @NEJM]

Neutralizing interleukin-10 autoantibodies were found in a subgroup of patients with inflammatory bowel disease and in no controls without IBD. Seropositivity was strongly associated with the IBD HLA-DRB1*01:03 risk allele. Full study results: https://t.co/C5oIChPFbG

Science behind the Study: Autoantibodies against Cytokines — From Infection to Inflammation https://t.co/Ja8nORGjYr

[NEJM @NEJM]

Paul Bastard, MD, PhD, and Jean-Laurent Casanova, MD, PhD, describe the scientific foundations of a study implicating autoantibodies against interleukin-10 in persons with inflammatory bowel disease.

Read the editorial “Autoantibodies against Cytokines — From Infection to Inflammation”: https://t.co/Ja8nORGjYr

[ShorterLab @ShorterLab]

The majority of axonal mitochondria in mammalian neurons lack mitochondrial DNA and do not produce ATP https://t.co/0PYl6YDm7X

[ShorterLab @ShorterLab]

Stress granule phase separation in stress-responsive cytosolic extract-in-oil droplets: https://t.co/jd4BOVkLNx

[Cell Biology J-Club @cell_club]

Mitochondria directly interact with the nuclear pore complex | Nature https://t.co/x9YeBPQ9kE

[Waggoner Lab @LabWaggoner]

p16High senescence-associated immune cells promote disease tolerance and healthy aging via TLR7 and STING control of adenosine concentrations @ImmunityCP
https://t.co/eWiEGS2GR3
https://t.co/paPRCMZY94

[Journal of Experimental Medicine @JExpMed]

CD301b⁺ monocyte-derived dendritic cells mediate resistance to #radiotherapy (https://t.co/D0ZcKL7DgQ). From Sirimuvva Tadepalli, Derek Clements, Juliana Idoyaga @Idoyaga_Lab et al. https://t.co/y57PEOehMj

📘 Part of JEM #Cancer Collection: https://t.co/6SoQAGNpOP
#EACR2026

[Cell Reports @CellReports]

Nociceptive neurons inhibit neutrophil extracellular trap formation via MLKL-licensed histone release https://t.co/bLYJcbSKaC

[ShorterLab @ShorterLab]

Structural motif search across the protein universe with Folddisco: https://t.co/Cu9lbSILyy

[Cell Biology J-Club @cell_club]

Vacuole pH loss triggers ESCRT-dependent plasma membrane remodeling to prevent amino acid toxicity https://t.co/dmzTpR2XpK

[Molecular Cell @MolecularCell]

A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer https://t.co/4LCJzCcwP2

[Journal of Experimental Medicine @JExpMed]

Chimeric MHC class I and II-restricted non-self epitopes broaden anti-tumor T cell reactions. From Rongsheng Zhang, Tasuku Honjo, Kenji Chamoto and colleagues: https://t.co/4n8kiUXxWP

📘 Part of JEM #Cancer Collection: https://t.co/G4kZuFwhgu
#EACR2026

[Merav Cohen Lab @MCohenLab]

We present Effero-seq, a novel approach combining #scRNA-seq with lysosomal acidification tracking by using pHrodo - a pH-sensitive fluorescent marker. This method allowed us to track gradual changes in macrophage gene expression driven by efferocytosis of apoptotic cells (ACs).