@sama@sama how about being able to highlight text directly. I archive contents but sometime I need to highlight paragraphs that I think are useful, insightful etc. please consider this feature.
Fascinating insights from @Brain1878! The early onset of proteasome dysfunction in Alzheimer's highlights a critical area for research. Understanding how this impairment escalates can lead to innovative therapeutic strategies.
Cool study! Investigating proteasome dysfunction highlights the importance of proteostasis in neurodegenerative diseases. Early intervention targeting proteasome pathways might delay Alzheimer’s progression. What are your thoughts on potential therapeutic strategies addressing this dysfunction? #Neuroscience #Medicine Discover more insights at https://t.co/4Y9Imt8uIJ—a comprehensive platform for all your biomedical questions and reviews.
Jiang et al. find that proteasome dysfunction occurs early in Alzheimer’s disease and worsens with disease progression, impairing the ability of neurons to clear harmful proteins. https://t.co/YpDVf9KMdd
🚨 After more than three months, Columbia University is no longer frozen out of NIH funds, per source.
Terminated grants will not yet be reinstated, but money should begin flowing otherwise, I'm told.
Announcing an official fundraising campaign to support my lab’s research on APOE4 and Alzheimer’s disease: https://t.co/cur6EcS2E0 This campaign is itself an experiment of sorts. But mostly, it's an attempt to save my lab during an unprecedented time of turmoil in academia. 1/9
Early Proteasome Gene Downregulation And Impaired Proteasomes Function Underlie Proteostasis Failure In Alzheimer's Disease https://t.co/tlDalZNhhN #biorxiv_pathol
Hi all. My friends (@yucanuck08@lfeldsmith@EiRuTorres) and I recently started a non-profit called Generation Brain. I’ll be posting over on that account for the remainder of AAIC, so follow us and come join in on the conversation!
Some of you may find it interesting. Our latest paper showing stimulation of 5-HT4 with Prucalopride (FDA-approved for constipation) can clear synaptic tau via proteasome.
https://t.co/77SZW4uZ5D
We are hiring postdocs! Come join us @Columbia in the New York City! Both experimental biologists and computational biologists are welcome to apply https://t.co/8zFXbHG1Hz
I am sadden to learn the death of Alfred Goldberg, a giant in the field of biochemistry and proteolysis. Fred has had a big influence in my scientific career and he was a good friend. Will miss you dearly.
https://t.co/nxU6S8TLxs