The Martin Ott lab

Research on the biogenesis of mitochondrially encoded proteins.
Find us on Bluesky: @mitolab.bsky.social

[OsmanLab @osman_lab]

🚀 Excited to share our latest work on Mrx6 and mtDNA copy number regulation, now available on @biorxivpreprint ! We uncover how Mrx6 and Mam33 interact with the Lon protease Pim1 to control substrate degradation. 🔬 Check it out here: https://t.co/jMAYrLoqUW #mitochondria #mtDNA

[The Martin Ott lab @Ott_MitoLab]

We have an open Postdoc position!
Join our lab in Gothenburg at the beautiful west coast of Sweden to work on an exciting project:
https://t.co/eNxTqEoefp

[The Martin Ott lab @Ott_MitoLab]

#MyXAnniversary We joined twitter exactly 6 years ago, now it is time to move on.
Find us in the future on bluesky: @mitolab.bsky.social
https://t.co/7lQpizCtCE
Thanks everybody for the past years by making science twitter a great forum!

[James A. Letts @LettsScience]

What are respiratory supercomplexes (SCs) doing?

Our collaboration with @Holab_DukeNUS shows that an extra large SC forms between complex I and complex III in a mouse model of complex III deficiency. SC-XL rescues the respiratory defect.

https://t.co/XvMRrDaBmx

[Pagliarini Lab @Pagliarini_Lab]

I'm excited to share our latest work linking TAG mobilization to mitochondrial stress recovery. A monumental effort by @Zak_Bakes (on the faculty job market soon!). Great collaboration with the @Coon_Labs and others.
https://t.co/4gnU2DgaG4
#mitochondria
#HHMINews

[The Martin Ott lab @Ott_MitoLab]

@carlstrm6 and I wrote a spotlight in @Cell_Metabolism on a recent paper from @puigserver_lab on respiratory supercomplexes in BAT that show substantially increased electron transfer efficiency. Here is a free link to the spotlight:
https://t.co/RuVXHcqxSK

[The Martin Ott lab @Ott_MitoLab]

@MuenchLab @goetheuni @IBC2_GU @EMBO_YIP @ERC_Research Fantastic, congratulations!!

[The Martin Ott lab @Ott_MitoLab]

This will be so exciting!! Thanks to @KAWstiftelsen for the support!

[Mito@GU @Mito_at_GU]

Exciting news from @SahlgrenskaAcad @goteborgsuni: Maria Falkenberg, Claes Gustafsson, @Ott_MitoLab
@ErikLekholm starting new collaboration on #mitochondrial gene expression. Generous funding from @KAWstiftelsen:
https://t.co/3sfuIu2yqs

[MokranjacLab @MokranjacLab]

Mark your calendars for this year's Walter Neupert Lecture🎊

[The Martin Ott lab @Ott_MitoLab]

Fantastic!

[Florent Waltz @FlorentWaltz]

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria! 
https://t.co/cxHl1j20CJ

[The Ban Lab @The_Ban_Lab]

In our new study we reveal how NAC coordinates and regulates successive co-translational nascent chain ⛓️ processing on the mammalian ribosome
out today in @Nature https://t.co/KXdYY1ZVHA
collab with @DeuerlingLab Shu-ou Shan @Caltech
@snsf_ch @ERC_Research @ETH_en

[OsmanLab @osman_lab]

🚀Excited to share our latest paper, where we explore dynamic changes in mtDNA heteroplasmy in living cells! Discover how asymmetric partitioning and mitochondrial dynamics drive mtDNA variant segregation! 🔬https://t.co/2jDc93D4Sr #Mitochondria #microscopy #microfluidics #mtDNA

[OsmanLab @osman_lab]

Awesome fun activity at the retreat with the @Ott_MitoLab at Tjärnö Marine Station 🔬🪸🪼🦀🦭

[The Martin Ott lab @Ott_MitoLab]

Just back from a wonderful retreat with the @osman_lab in Tjärnö on the Swedish west coast @GothenburgMBL. Three days of scientific discussions around mitochondrial gene expression and maintenance, beautiful scenery and lots of fun. Thanks to everybody for the good times!!

[The Martin Ott lab @Ott_MitoLab]

@LabScorrano @ERC_Research @DiBio_UniPD @VIMMPadua @mitoPhD_Keisuke Congratulations Luca!! Exciting!

[ZMBH - Center for Molecular Biology Heidelberg @ZmbhH]

New paper from the Vögtle lab on how Synchronized assembly of the oxidative phosphorylation system controls mitochondrial respiration in yeast: Developmental Cell https://t.co/w6sGE3Lxhd

[AndréassonLab @AndreassonLab]

Very happy to share our latest findings: A novel chaperone – Chp1 – functions at the ribosomal tunnel to safeguard the biosynthesis of abundantly expressed eEF1A. Great collaboration with @BukauLab
@hauryliuk and many others! https://t.co/CdfFj5dT1O

[The Martin Ott lab @Ott_MitoLab]

Congratulations Dr. Andreas Carlström, PhD thesis✅ Thanks for being such a force in the group! And thanks for a great discussion by the opponent Chris Meisinger, Freiburg University, and the committee, Gunnar von Hejine @Stockholm_Uni, @krijonas and Joanna Rorbach @MolMet_KI !!