Daan Overwijn

Ph.D. student at the Biozentrum, Basel

[Daan Overwijn @OverwijnDaan]

How does an mRNA become “cytoplasmic” after leaving the nucleus?

Our new preprint identifies PAIP1 as a factor that couples mRNA export to poly(A)-binding protein exchange, mRNP maturation, poly(A)-tail control, and early development.

https://t.co/W9nEdCZigp

[Hong Yue @HongYue88665668]

This is wonderful collaboration with @RPNowak we thank all the patients who donated their samples, institutes who have made this study possible @DanaFarber @ragoninstitute @MassGenBrigham and amazing colleagues @Chemist_Payne @mazit @IreneGhobrial @fischerlab1 @RomanosSP et al.

[Hong Yue @HongYue88665668]

I'm so exited to present our biochemical assay in clinical diagnosis. Great collaboration with @RPNowak @eric_fischer @mazit @Chemist_Payne @fischerlab1 @DFCI_ChemBio @HMS_BCMP
Diagnostic TR-FRET assays for detection of antibodies in patient samples: https://t.co/5EPtGwxfW8

[Moritz Hunkeler @moritzhunkeler]

And it's out! 🍄 Our BIRC6 story out in @ScienceMagazine today!

https://t.co/H2wJqj4es1

[Maria Hondele @MariaHondele]

Curious about “DEAD-box ATPases as regulators of biomolecular condensates and membrane-less organelles”? We proudly present the first review from the lab, and it was great fun reading & writing with @OverwijnDaan!
https://t.co/onlsfFKZlI

[Daan Overwijn @OverwijnDaan]

@kbrogala @mlvalenstein Congrats!!!

[Daan Overwijn @OverwijnDaan]

@kbrogala @StanfordMed Congrats Kacper!

[Daan Overwijn @OverwijnDaan]

I am honored to have a small contribution to this team and paper that is online now! @moritzhunkeler @fischerlab1 Thanks everybody for the awesome time I had in the Fischer lab!!!

[Moritz Hunkeler @moritzhunkeler]

Almost one full year after the preprint (🚽), we can finally present the final version of our HUWE1 manuscript!

Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition https://t.co/1mejGogt18

[Molecular Cell @MolecularCell]

Online Now: Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition https://t.co/JcpnmMfnEu

[NCCR RNA & Disease @NCCR_RNADisease]

We welcome @MariaHondele (@biozentrum, @UniBasel_en ) as a new Associate Member of the NCCR RNA & Disease. Her lab studies the formation and function of membraneless organelles, especially ones associated with RNA processing.
Hondele lab website:
https://t.co/i4W7xGBjjN

[Katherine A Donovan @kdonovan1008]

We are extremely excited to share our recent work mapping the degradable kinome! Here, we provide chemistry and global proteomics for 91 kinase-targeting degrader molecules demonstrating degradation of over 200 different protein kinases. @CellCellPress
https://t.co/8KgG4GdDUs

[Sanne van der Rijt @Sanne_vdRijt]

Happy with our review on the interrelation between mitochondrial dysfunction and the other hallmarks of aging!