Rachel Stephenson

cell biologist at UMich, podcast lover, improv enthusiast

[Rachel Stephenson @RachlStephensn]

Our paper "Rho flares repair local tight junction leaks" is now online @Dev_Cell! https://t.co/9QsXF6sp4Z

More here: https://t.co/WrjtXbJ4F4

And finally, some imaging of Rho flares in #Xenopus embryos. Active Rho is in green, tight junction in magenta. Arrows point to flares.

[P.E. Moskowitz @_pem_pem]

my main issue i care about beyond all the other more important issues in the world is that headlights are way too bright now and it feels insane that everyone’s cars are just constantly blinding each other as they pass

[Rachel Stephenson @RachlStephensn]

@cytoskeletown LOI interpolator in the Time Lapse plugin in FIJI has worked well for me. Trace your wiggly thing with segmented lines on a subset of frames, and it'll fill in the rest and make a kymograph

[Jennifer Landino @jenelandino]

The Landino lab is hiring! 🎉 We are looking for a technician to start when we open our doors this fall. Please share the ad with folks you know who are interested in reconstitution, model organisms, and live imaging!

https://t.co/eqyeAbAkjv

[Sen. Bernie Sanders @SenSanders]

No graduate student worker should be living in poverty while the University of Michigan sits atop a $17 billion endowment. These 2,500 workers deserve safe working conditions and living wages. The University must bargain a fair contract immediately.

[Helen Willsey @goodfrognosis]

Yesterday I decided to stop editing out all the exclamation marks in my emails. I’ve done this for years to seem “more professional.” But what does that really mean???? Less female? Less young? Less excited? Well I’m young and female and IM EXCITED!!!!!!!!!!!!!!! Get used to it.

[Woolner Lab @LabWoolner]

Interested in how mechanical forces regulate cells and tissues? We're looking for a postdoc, ideally with experience in proteomics, to join us in the Woolner lab.

https://t.co/V9OBoVfpwa

[Jennifer Landino @jenelandino]

I'm excited to share that the Landino Lab will officially open this summer at at Dartmouth Geisel School of Medicine in @DartmouthBCB We will investigate cytoskeletal dynamics and cell division using Xenopus 🐸 We're recruiting at all levels - please share!

[Rachel Stephenson @RachlStephensn]

@Cristaraya1 If you're just looking to label apical junctions, I love BFP & RFP-ZO1 for looking at tight junctions. Can't think of anything we have that labels the whole apical domain, though, if that's what you're after.

[Rachel Stephenson @RachlStephensn]

For anyone who's ever asked which GEF is activating Rho flares, here's your answer, courtesy of @ShahanaChumki1 & co!

[Shahana Chumki, PhD @ShahanaChumki1]

Meet the labor of my love! Really excited that this paper is out to continue the story of #RhoA flares from The Miller Lab @UMich_MCDB!

p115RhoGEF activates RhoA to support tight junction maintenance and remodeling https://t.co/LwqerM0Ieh

[Rachel Stephenson @RachlStephensn]

@NeuTubeChannel @jenelandino This paper identifies the likely epitope via yeast two hybrid, which is highly conserved in IIA, IIB, and smooth muscle myosin.

https://t.co/WsXYFXTbFW

[Rachel Stephenson @RachlStephensn]

Check out our latest work on Rho flares! Fantastic imaging of Rho & calcium dynamics by Sara @saranya_raajan and beautiful optogenetic Rho activation by Shahana @shahanachumki1 All possible thanks to our favorite model organism! 🐸 #Xenopus @frogwranglers

[Journal of Cell Biology @JCellBiol]

Using live imaging, optogenetics, & laser-induced tight junction injury, @saranya_raajan, Ann Miller et al @UMich_MCDB show that mechanosensitive channel-dependent calcium flashes promote sustained local activation of RhoA and tight junction repair https://t.co/lx6IyC0RVU

[Rachel Stephenson @RachlStephensn]

Such cool work, and I love the concept of natural history being applied to cell biology! I hadn't heard that before.

[Zac Swider @ZacSwider]

Our latest preprint from the @BementLab: Here we combined high speed live imaging with computational analysis to investigate the natural history of cortical excitability in developing frog embryos. The movie below shows an embryo labeled for F-actin.
https://t.co/0mGySp734A

[Mark Budde 🦕🏆 @markwbudde]

Primordium is now offering everyone the chance to sample our full-plasmid sequencing service for FREE - never use Sanger sequencing again! Please retweet this message and we'll DM you a coupon to sequence 5 ENTIRE PLASMIDS 100% FREE, no CC or PO needed. https://t.co/U4WeR2ftjL 5/

[Rachel Stephenson @RachlStephensn]

Great speaker lineup!

[Tetsuhisa Otani @tetsuotani1]

Please RT! Registration for the 51st NIPS International Symposium "Frontiers in Epithelial Cell Biology" (online, December 6-8, 2021) is open! Leading researchers studying various aspects of epithelial biology will gather. Please register by November 12! https://t.co/pILNjUtBab

[Saranyaraajan Varadarajan @saranya_raajan]

Very excited to share our new pre-print on how mechanosensitive calcium influx serves as a mechanism to sense and respond to leaks in epithelial barrier!!!

[Jennifer Landino @jenelandino]

New pre-print from the Miller lab @UMich_MCDB. Awesome work by @saranya_raajan investigating the role of calcium in repairing tight junctions in the frog embryo 🐸💥

[Ivan Alcantara @ivancalcantara]

I think all scientists working on feeding and obesity research should take a seminar on fatphobia.

[Rachel Stephenson @RachlStephensn]

Great post by my labmate Suzie on what it's like to be hard of hearing in STEM

[American Society for Cell Biology @ASCBiology]

The sound of science: How hearing impacts scientists, a new blog from Suzie Craig @suzieq7190
https://t.co/kqecjfKuCT

[Rachel Stephenson @RachlStephensn]

Check out Jen's preprint for more mesmerizing videos and the cool science of in vitro reconstituted Rho and actin waves.
Congrats @jenelandino !

[Jennifer Landino @jenelandino]

We found that extract reconstitutes cortical patterning previously only observed in cells and these patterns are generated without any exogenous signals 🤩

[Helen Willsey @goodfrognosis]

Check out our latest work using Xenopus tropicalis to identify convergent mechanisms of risk and resilience in autism. With many thanks to Matthew State, @gastrulateordie @WillseyLab @LabNowakowski @UCSFPsychiatry @QBI_UCSF @NIMHgov @UCSF https://t.co/rRZMbwWfwh