Xiao Li

Asst. Professor @Texas_Heart at Baylor College of Medicine | Cardiac biology, Immunity, Genomics | Love outdoor photography, all living things | Views’re my own

[Steven Ge @StevenXGe]

Spatiotemporal gene expression and cellular dynamics of the developing human heart

https://t.co/dTCudcphu2

[Xiao Li @SirScienceAlot]

Our new study with the Martin Lab uses spatial single-cell omics to dissect the cellular architecture of cardiac fibrosis in the atria. Grateful for a great collaboration and congratulations to Chang-Ru and the team! 🎉

[Chang-Ru Tsai @ChangRuTsai1]

Excited to share our latest work! Thank my mentor @jmartinlab and all the colleagues @linliucns, @RichGangLi , @Fansen2020 and collaborators @SirScienceAlot and Dr. Jun Wang and Dr. Hassan Samee.

https://t.co/7foP2SppoX

[dana_peer @dana_peer]

This method is awesome

[Xiao Li @SirScienceAlot]

Congratulations to the team! Another piece of our pediatric HF studies

[H.J. Tadros @hj_tadros]

Excited to share our @Circ_Gen article profiling end stage hypertrophic cardiomyopathy 🫀in 👶🏻 with snRNA-seq 🧬

https://t.co/RsiKqkMAlb

Thank you to our team @jmartinlab , @SirScienceAlot , @DiwakarTuraga

#CardioTwitter #Genetics @TCHheartcenter @BCM_CVRI

[Xiao Li @SirScienceAlot]

Interesting concept👍

[Xu Zhou (周旭) @XuZhouLab]

Glad that our paper is officially out @CellCellPress. BRD4 condensate functions as a pH sensor to tune inflammatory response in macrophage. https://t.co/Z6GhhU7hQD
earlier post: https://t.co/p8sim9ayaq
and could-have-been cover by my student&artist Cathleen Krabak @harvardmed

[Jennifer Guerriero, PhD @JennGuerriero]

PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the aforementioned M1/M2 states. M1/M2 language causes confusion and sets the field back. Refer to your macrophages by the molecules they express and the cytokines they make.

[Yanxiang Deng @DengYanxiang]

Spatial-DMT is now published in @Nature ! For the first time, we can simultaneously map DNA methylation and RNA transcription in tissue context. Great collab with @zhouwanding lab. Big congrats to Chin @Chin72155594 , Hongxiang @HongxiangFu and team! https://t.co/9K1vtltSqG

[Matthias Nahrendorf @MatthiasNahrend]

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS https://t.co/pI5jDMrpun

[Xiao Li @SirScienceAlot]

Game changer for functional genomics!

[Jun Cheng @s6juncheng]

Excited to share #AlphaGenome, a start of our AlphaGenome named journey to decipher the regulatory genome! The model matches or exceeds top-performing external models on 24 out of 26 variant evaluations, across a wide range of biological modalities.1/6

[Xiao Li @SirScienceAlot]

A key post-transcriptional mechanism in pediatric cardiomyopathy. Congrats to the Jang Lab🎉🎉🎉

[Jihyun Jang @JihyunJang_JJ]

Our lab’s first discovery is out today! We identified cardiac m6A methyltransferases as a novel gene regulatory layer in heart development. More mechanisms await discovery! @Deqiang8 @AccorneroLab @heewlim @ViduGargMD @SirScienceAlot https://t.co/duACwAA2Kl

[Xiao Li @SirScienceAlot]

Interesting tool

[Ming "Tommy" Tang @tangming2005]

A visual–omics foundation model to bridge histopathology with spatial transcriptomics https://t.co/r6PdyMEHkg

[Nature Cardiovascular Research @NatureCVR]

Research| Jimenez et al. show that CD40 agonists can induce myocardial inflammation by activating cardiac macrophages and CD8 T cells, sensitizing the heart to secondary injury and promoting adverse remodeling.

👉https://t.co/pHbSFf5Bc0

[Massimo @Rainmaker1973]

Watch a killer T cell of the immune system destroying a monstrous ovarian cancer cell.

[🔬 Alex Ritter / RitterLab]

[nature @Nature]

An Australian man in his forties has become the first person in the world to leave hospital with an artificial heart made of titanium

The device could be a temporary measure for those waiting for a donor organ

https://t.co/NwfcRpm3yF

[Xiao Li @SirScienceAlot]

@jonathankirk Congratulations 🎉

[Xiao Li @SirScienceAlot]

@FengXiao1000 @American_Heart @williampu66 @sarah_morton @PulaB Congrats. Well deserved 👍

[Xiao Li @SirScienceAlot]

@MasonSweatPhD Awesome 👏 welcome to texas!!

[Xiao Li @SirScienceAlot]

@JihyunJang_JJ Excellent news!

[Joseph C Wu, MD, PhD @Joseph_C_Wu]

At a critical time for scientific research, the new American Heart Association Presidential Advisory emphasizes medical & economic benefits of @NIH funded research
https://t.co/BdOIZktxY7
@AHAScience @HeartNews @StanfordCVI @American_Heart @StanfordMed @CircAHA @HeartBobH

[Xiao Li @SirScienceAlot]

Excellent work! Congratulations!

[EdT @thorplab]

Early-age efferocytosis directs macrophage arachidonic acid metabolism for tissue regeneration: Immunity https://t.co/bFdshKI0Ua