Wigard Kloosterman

Genome scientist and biotech entrepreneur

[bioRxiv Genomics @biorxiv_genomic]

The complete sequence of a human genome https://t.co/4MFonDegtI #biorxiv_genomic

[Wigard Kloosterman @WigardK]

Happy to share SHARC, a method for rapid identification of tumor-specific genomic structural variants using low-pass @nanopore sequencing https://t.co/QgWyrCLpXP @Jaesvi42 @Ch_Stangl @MartijnLolkema

[Christian Gallardo @MrGalloLA]

Introducing MrHAMER, our @nanopore-based high accuracy viral sequencing platform that yields single-molecule reads to ≥99.9% accuracy. Truly a team effort at the @BruceTorbett and @AndrewRouth labs. A thread 🧵...
https://t.co/SYeVB19cNJ

[The Kloosterman Brothers @kloostermanbro1]

#MerryChristmas.   May this #christmas #song inspire you.
#InspireUs #christmassong

https://t.co/qnkwi1P4FZ

[bioRxiv @biorxivpreprint]

A multi-platform reference for somatic structural variation detection https://t.co/GJhlFy1K8r #bioRxiv

[Cees Dekker @cees_dekker]

Our latest #CDlab paper is on @arxiv: https://t.co/VzP66nIGMe

PhD student Nils Klughammer developed Pd Zero-Mode Waveguides for optical detection of single fluorophores, proteins, DNA in multiple colors with superior signal-to-noise compared to ion-current detection in nanopores

[Christina Stangl @Ch_Stangl]

FUDGE is out! Happy that our assay for rapid fusion gene detection using @nanopore sequencing got published today @NatureComms
Thanks to @gmonroe3 @GijsvanHaaften @WigardK @anton_gh @Jaesvi42 and EVERYONE else, it was fun working with you!
https://t.co/UTxbeJbm8A

[Maike Sander & Lab @msanderlab]

Check out our latest work with @HubnerLab @MDC_berlin on the role of long noncoding RNAs (lncRNAs) and #lncRNA-encoded #microproteins in human #pancreas development! A short thread  1/9
https://t.co/0Y6FmhLI5A

[Wigard Kloosterman @WigardK]

M'n pa speelt het #Wilhelmus2020 op het mooie Van Oeckelen orgel in de Kloosterkerk van Ter Apel. Vrolijke Koningsdag!! #koningsdag2020

[CureVac Netherlands @CureVacNL]

Frame is happy to announce a new research collaboration with eTheRNA immunotherapies NV to develop mRNA cancer vaccines against immunogenic neoantigens. Read more on our website: https://t.co/922vsrc4MA

[Wigard Kloosterman @WigardK]

Large differences in #coronavirus estimated mortality rates across countries, probably largely due to underestimating cases in some countries

[Ilya Kirov @ilyavkirov]

TALC: Transcription-Aware Long Read Correction https://t.co/lFYuencZFG

[Hartwig Medical @HartwigMedical]

@RPlasterk op bezoek in het high-tech laboratorium van @HartwigMedical

[Ellen @EllenStelloo]

Want to know more about the molecular characteristics of ovarian granulosa cell tumors? Check out our manuscript. #medrxivpreprint #UMCU_CMM https://t.co/aTBXx1fUlK

[Hartwig Medical @HartwigMedical]

“Het is echt een hele goede investering als we in het zorgsysteem deze test vergoed kunnen krijgen” @LeonieSazias en Emile Voest van @hetAVL vertellen bij OP1 waarom ze vinden dat kankerpatiënten een uitgebreide DNA-test zouden moeten krijgen https://t.co/eO8N6xnIsU #wgstest

[Alexander Hoischen @ahoischen]

We call it: Next generation cytogenetics!
Very proud of our amazing team here. We used Bionano’s genome imaging technology to test 48 clinically well studied leukemia samples to test its utility: https://t.co/FKIoBaDohg

[Matt Loose @mattloose]

Read Until to enrich >700 genes to mean 30x coverage on @nanopore single flowcell. Custom panels (up to 25,600 targets so far) as easy as providing a coordinate file. Read more at https://t.co/aZVOs23PKg - thanks to @alexomics, @Rorymatics and @DeepSeqNotts team.

[Oxford Nanopore @nanopore]

Today we’ve introduced R10.3 flow cells to the store. Building on R10 — which was recently shown to produce 99.995% single molecule consensus accuracy — R10.3 provides increased throughput and better raw read accuracy. Read more: https://t.co/HCGcPptPjB

[Edwin Cuppen @ecuppen]

Application of CHORD on the @HartwigMedical whole genome sequenced cancer cohort reveals Pan-cancer landscape of homologous recombination deficiency. 30% of HRD in ovarian cancers and 12% in breast, but also 13% in prostate and pancreatic cancer. https://t.co/RBjT0oB2ad