Christina Stangl

[PrinsesMáximaCentrum @prinsesmaximac]

June 12-13 👉 Scientific Symposium - Improving pediatric cancer care by scientific excellence: https://t.co/NtZ7Pr5cV0
Showcasing: Latest developments and technologies
Reflection: Status of pediatric oncology
Discussion: Opportunities for the future
#pediatriconcology #siop

[Christina Stangl @Ch_Stangl]

Great to see this work published!

[Wigard Kloosterman @WigardK]

Happy to share SHARC, a method for rapid identification of tumor-specific genomic structural variants using low-pass @nanopore sequencing https://t.co/QgWyrCLpXP @Jaesvi42 @Ch_Stangl @MartijnLolkema

[bioRxiv @biorxivpreprint]

A multi-platform reference for somatic structural variation detection https://t.co/GJhlFy1K8r #bioRxiv

[martin elferink @martinelferink]

Happy to share our latest work: CyclomicsSeq!
Great collaboration between groups in the UMC Utrecht including @UMCUgenetica @UMCU_CMM @oncodeinstitute and off course @cyclomics.

[Edwin Cuppen @ecuppen]

Distinct genomic profiles are associated with treatment response and survival in ovarian cancer https://t.co/5PFbAzTICQ @UMCU_CMM @HartwigMedical

[Christina Stangl @Ch_Stangl]

Rapid identification of the partner gene of fusions helps improve diagnosis, prognosis and offers opportunities for treatment. The exact GENOMIC breakpoint can be used as a marker that allows diagnostic labs to design patient-specific assays for minimal residual disease tracing!!

[Christina Stangl @Ch_Stangl]

FUDGE is out! Happy that our assay for rapid fusion gene detection using @nanopore sequencing got published today @NatureComms
Thanks to @gmonroe3 @GijsvanHaaften @WigardK @anton_gh @Jaesvi42 and EVERYONE else, it was fun working with you!
https://t.co/UTxbeJbm8A

[Christina Stangl @Ch_Stangl]

To reduce cost, we designed a barcode-independent multiplexing approach. With this, we can pool 4 samples in one sequencing run.

[Gijs van Haaften @GijsvanHaaften]

Nieuwe techniek spoort fusiegenen snel op - UMC Utrecht https://t.co/MNmQuANCuX

[Adam Ameur @_adameur]

Excited to share our preprint on #CRISPR-Cas9 activity and long reads! We developed protocols for @PacBio and @nanopore off-target sequencing (SMRT-OTS & Nano-OTS) and found unexpected Cas9 cleavage. A lot of work went into this, by @idaista and others
https://t.co/JVJeHFbRcO

[Matt Loose @mattloose]

Read Until to enrich >700 genes to mean 30x coverage on @nanopore single flowcell. Custom panels (up to 25,600 targets so far) as easy as providing a coordinate file. Read more at https://t.co/aZVOs23PKg - thanks to @alexomics, @Rorymatics and @DeepSeqNotts team.

[Christina Stangl @Ch_Stangl]

Super big thanks to Jasmin Post, Emile Voest, @Snippertlab, @WigardK and everyone who joined the efforts!

[Christina Stangl @Ch_Stangl]

BRAF fusion ≠ BRAF fusion! Happy to share our manuscript showing how (and that) fusion gene partners influence fusion gene activity. Online today @MCR_AACR, check it out: https://t.co/cYEZA3TfQk

[Oxford Nanopore @nanopore]

From the microbes of Iceland’s polar icecaps, to meningitis ID in Vietnam. From rapid cancer characterisation to food safety. From 1000s of human genomes, to the tallest trees in the world – we'd like to share our 19 highlights of 2019: https://t.co/9tFaJ9UuWk

[Joske Ubels @JoskeUbels]

Our new work identifying a gene expression signature to predict proteasome inhibitor benefit in Multiple Myeloma (validated in independent data!) is now online at medRxiv! @jeroen_deridder @UMCU_CMM @oncodeinstitute @skylinedx https://t.co/MZxvDigfI1

[Ellen @EllenStelloo]

Very happy to share our latest work @medrxivpreprint in which we studied the capacity of ovarian cancer #organoids to predict patients’ chemotherapy response and functional consequences of tumor heterogeneity @UMCU_CMM @_Hubrecht

https://t.co/DsRUTdmzDZ

[medRxiv @medrxivpreprint]

Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses https://t.co/cz75ayzua8 #medRxiv