Principal investigator@Wuhan University, China. |Previously @salaitalab @ Emory University, US.| We are working on cell mechanics, Single-Molecule biophysics.
Macrophages can engulf targets whole (phagocytosis) or nibble them in small fragments (trogocytosis), a decision controlled by cortical tension in the targets (high tension favors former, low latter)
https://t.co/bWqUvSxpRs
https://t.co/eBZHkmmHb6
@NatureCellBio@UCBerkeley
Fibroblasts aren’t always slow — by tuning integrin ligand spacing and force-limited bond lifetime, we boost their migration up to 12×. A new 2D framework for adhesion-regulated motility.
| PNAS https://t.co/gqucGZq94G
Happy to share our latest work, 4Pi-SIMFLUX, which combines structured illumination with interferometric detection to achieve near-isotropic 3D localization precision of 2–3 nm and resolve sub-10 nm structural features in cells. https://t.co/OlSHOstvww
https://t.co/LLduUw3ohG
📣 The Springer Lab is hiring!
Advance groundbreaking research at the intersection of integrin signaling, organoid development, and cell surface receptor mechanobiology.
https://t.co/y8G4xKeLuI
#postdocjobs, #academictwitter, #ECRchat, #phdchat
🌟 Excited to announce the East Asia Single-Molecule Biophysics Symposium 2025 (EASMB 2025)!
📍 Singapore
🌐 Info & details: https://t.co/GgN0RdPeUc
📌 Abstract deadline: Sept 12, 2025
✉️ Register: [email protected]
Check it out at PNAS today. Thank you Alexandre for the collaboration!!
PK Mem probes offer long time-lapse imaging of cell membrane dynamics. Made possible by @JingLing369, Yitong Liu, and all the collaborators!
Available @spirochrome
It’s finally out!!🥳
Check out our paper in @NatureMaterials on a new hybrid scaffold where we discover ECM-specific cues that regulate cardiac aging
🔗 https://t.co/Vgf1ZEersw
This is the lab’s 1st research paper, led by my 1st @NUSBME PhD student @AveryRuiSun🤩
Tweetorial👇
We just published a review on recent progress in integrin force loading rate measurement using various molecular tension probes. Learn more about how this has advanced the field and what potential improvement lies ahead here: https://t.co/HLIKLwxf7B
#mechanobiology
Our extensive review on "Computational Super-Resolution: An Odyssey in Harnessing Priors to Enhance Optical Microscopy Resolution" is online at https://t.co/aaCtesITHp Wenfeng put a lot of heart and soul into it. So I believe that it is worth reading😀
We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! https://t.co/hpFUqyuRGD The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC@myESMO@ASH_hematology
Thrilled to share our back-to-back two Nature @Nature papers on the unexpected role of type 2 immunity against cancer. We found that interleukin 4 (Fc–IL-4), a type 2 cytokine, reinvigorates exhausted T cells to potentiate anticancer immunotherapy w/ @YugangGUO2@RongFan8(1/11)