Elena Sou

PhD student from Macau🇲🇴; studying meiosis, gene ON/OFF and cancer @livuniISMIB @ASTARsg

[Urszula McClurg 🇺🇦 @UrszulaMcclurg]

There is a new doctor in the house! Congratulations to @_Elena_Sou on passing her viva! First student to finish a PhD from our lab in Liverpool ☺️. Enormous gratitude to both examiners @mort_richard and @Pseudoenzyme who made it such a nice experience for Elena

[Emil Marklund @marklundem]

Read all about our latest work on protein-DNA binding 🧬, where we find that association dominates the binding process. Now out in @ScienceMagazine!

https://t.co/zWSLRIl6HA

A thread summarizing the findings.

[Mathieu Lupien @MatLupien]

Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks https://t.co/woIk7dLmgc

[Harry Leitch @HGLeitch]

Really happy to see this out @ Sexual Development @KargerPublisher

https://t.co/TTxJzwPcrn

Our overview of epigenetic regulation in gonadal PGCs with @ericmiskalab @ericmiska @NavinBrian @Keir_M_Heath.

Thanks to @gonen_nitzan for the opportunity :)

It is long!

[Urszula McClurg 🇺🇦 @UrszulaMcclurg]

Very excited to share our lockdown baby! @_Elena_Sou has done a great job compering nomenclature and timing of meiosis between different model organisms. Massive thanks to the reviewers and @Biochem_Journal for a lovely publishing experience! https://t.co/629AvIi45X

[CTCF Papers 📚 @CTCF_Papers]

BORIS/CTCFL expression activates the TGFβ signaling cascade and induces Drp1 mediated mitochondrial fission in neuroblastoma https://t.co/zYCG0n6QJ0

[Nature Reviews Genetics @NatureRevGenet]

Soma-to-germline RNA communication https://t.co/J4T3SycjLr #Review by @ColinConine & @ollie_rando @PennGenetics @ChildrensPhila @UMassChan

[Abdulkadir Abakir, PhD @A_Abakir]

Our News & Views
"SWI/SNF complexes as determinants of R-loop metabolism" is out @NatureGenet
https://t.co/DxKypQk7Df

Regarding https://t.co/NMjcobUioD by the @AguileRloop lab

Special thanks to @AlexeyRuzov for the invitation to contribute and @ReikLab for support!

[Urszula McClurg 🇺🇦 @UrszulaMcclurg]

Excited to be presenting our work from @_Elena_Sou and @_rmprice at the joined 23rd International Chromosome Conference (ICC) and the 24th International Colloquium in Animal Cytogenetics and Genomics (ICACG). You can register here for free https://t.co/rMho9AfWvX

[meiosispapers @[email protected] @meiosis_papers]

The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis | Samuel Rivero-Hinojosa | https://t.co/ZYzPcYnwPt

[Thomä Lab @LabThoma]

How do DNA-binding proteins engage specific sites “hidden” in chromatin? Recent cryoEM studies shed light on mechanisms @KurumizakaLab @CramerLab TaipaleLab, @SchubelerLab @LabThoma
https://t.co/na0AzW7OKq

[Martin Taylor @mst_paralogue]

Germline structural variant breakpoints and short insertions highly enriched at spermatogonial TFBS. Preferentially disrupt neuronal enhancers. Preprint: https://t.co/XeNcnjJIpF might relate to new Spo11 double-cutting insights: https://t.co/YCCAOYrvIj https://t.co/slOt55CEqw

[James Davies @jojdavies]

Delighted to share my lab’s @jdavieslab first big paper in @Nature!

We’ve developed a new 3C technique called Micro Capture-C that can generate base pair resolution 3C data https://t.co/Mgr26d2bTE

[Nucleosome papers 📚 NucPosDB database @Nucleosome_Bot]

The histone variant H2A.W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation https://t.co/vwPcZ3YAiL

[Epigenetics Research at Helmholtz Munich @epigeneticsHMGU]

Curious to know how to make #totipotent cells in a dish? Check out the paper of Dr. Ane Iturbide, @METorresPadilla, @anto_scial, @HadianKamyar and co in @NatureSMB. Congratulations 🥳 Collaborative effort truly pays off.
https://t.co/IZtnTdjzjs

[Shiv Grewal @grewalsh]

DENSITY MATTERS!!
A critical density of methylated histones (H3K9me3) is required to transmit epigenetic memory through the "read-write" mechanism. We show a direct role for modified histones in epigenetic inheritance.
https://t.co/arE8gLGCuG

[Gene Regulation @generegulation]

Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions https://t.co/c57YtHiQE4
✅ OCT4 is required for a subset of loop anchors
✅Disruption of OCT4 phase separation disturbs TADs & reprogramming which can be restored by phase rescue via IDR fusion

[Elena Sou @_Elena_Sou]

@HammedBadmos Enjoy Glasgow!

[Cell @CellCellPress]

New Resource out now! #CRISPRoff programs heritable #epigenetic memory and is able to heritably silence #genes through differentiation of iPSCs into #neurons https://t.co/zwpnfeIu7C
@JswLab @UCSF

[Ian Chambers @ianpaulcha]

Come join us and make new discoveries at the intersection of #chromatin #pluripotency and #stemcells