Matt Burnett

Chief Technology Officer

Dotmatics - Software for Scientists

[Matt Burnett @_mattburnett]

@amyohconnor I get this when I accidentally eat both the belgian buns from coop

[Dotmatics @dotmatics]

Thomas Swalla, CEO of Dotmatics, bylined an insightful article with Fox News Media on what to understand about AI and how it might help develop new, cost-effective drug treatments. Click to learn more!

https://t.co/CZ8FPwrKTN

[Dotmatics @dotmatics]

Today Dotmatics announced the launch of Dotmatics Luma™, a revolutionary new scientific data platform that helps scientists and administrators in life sciences unify and analyze large volumes of data for better decision-making. Learn more about Luma here: https://t.co/gKT0Xh1E8M

[Bo Wang @BoWang87]

🎉Exciting Update of scGPT 🎉: After receiving significant attention from the community since our April release, we're thrilled to announce the first major update for scGPT - a foundation model for single-cell multi-omic data.

This update integrates community feedback and leverages the latest data release from @cellxgene. It boasts larger pretraining data, and more robust models, and expands the range of application tasks.

Pre-print (V2) available: https://t.co/4aB2c4ZgJy
Access our open-source code and models here: https://t.co/13n0bJvgT2
Detailed tutorials: https://t.co/enNqXqXkdY

Highlights of this update include:

🔬 Introducing the first GPT-style foundation model for single-cell multi-omic data, pretrained on over 33M human cell atlas data.

💡 Our generalist approach enables one model to accomplish multiple tasks in single-cell analysis, including multi-omic integrative analysis and perturbation prediction.

🧬 Discovering gene-gene interactions specific to various conditions using learned attention weights and gene embeddings.

🚀 Uncovered a scaling law showcasing continuous model performance enhancement as data volume increases.

🐾 scGPT model zoo (see github) now offers multiple pre-trained foundation models for various solid organs and a comprehensive pan-cancer model. Begin exploring your data with the most fitting foundation model.

We welcome your thoughts on specialist vs generalist approaches in single-cell studies. Many thanks for the following technical analyses of scGPT:
1. Excellent twittorial by @simocristea: https://t.co/ICq3V78oxG
2. Comprehensive review on LLM in cell biology by @s_batzoglou: https://t.co/xtl5WCXijC
3. Insightful blog by @SalvatoreRaieli: https://t.co/7v8PRv9NNc

Kudos to Haotian (@HAOTIANCUI1) & Chloe (@chloexwang1) for their exemplary work on this project. @VectorInst @pmcc_ai @UHNAIHUB @bradwouters @drbarryrubin @UofT_TCAIREM @UofT_LMP @UofTCompSci @uoftmedicine

[Werner Vogels @Werner]

When I speak with developers about generative AI, much excitement is around automating away the “boring” stuff. The boilerplate code. The repetition. And focusing on hard problems. It’s no different for folks in IT or security. With AWS AppFabric, we’re making it much easier to manage and secure SaaS apps in a no-code environment and significantly reducing the need to create custom point-to-point app integrations. Less overhead means more time spent working on things you’re actually interested in, and it's an area where generative AI is already playing an important role. https://t.co/DbgaXSYvR2

[Angelos Georgakis @angelosgeo]

Biotech CEOs:

Don't let the macro/fundraising environment dictate the vision of your company.

The macro environment will always be a forever-changing thing.

Don't build your company "for the current environment".

You build for the patients; patients need you now, tomorrow and in every "current economic environment".

Don't change direction because "it will be easier".

You've signed up for a 15-20 year Odyssey to redefine human health.

It will always be hard for you, regardless of the economic environment and other external stuff.

Of course, you should consider the weather when navigating the ship... but you can't let the weather dictate your Ithaca...

Loving you, Angelos.

[Bob Gantzer @gantzer16]

Great article in @NatureBiotech on how, and why, we must move past viral delivery to truly realize the promise of the genetic medicine revolution.

Our work at @AeraTx is featured and this is something we are working on every day.

https://t.co/FZDC5WoYxF

[Rob Mac @RMcElhenney]

Never a doubt. Congratulations @Official_NCFC !!!!!!! What an extraordinary run. See you next year ;)

[Ryan Reynolds @VancityReynolds]

Congratulations @Official_NCFC!!!! What a game, what a season, what heart. We will see you in the EFL next. 🔥

[Matt Burnett @_mattburnett]

@Official_NCFC Amazing!!!

[Notts County FC @Official_NCFC]

WE'VE DONE IT!!!!!

[Matt Burnett @_mattburnett]

Effort.

[Matt Burnett @_mattburnett]

@alexandrakuri @dank_ackroyd my whole year.

[The Labour Party @UKLabour]

Three things to remember today:

✅ Polls are open from 7am-10pm
✅ You'll need photo ID with you to vote
✅ Vote Labour

[FierceBiotech @FierceBiotech]

2022’s list of biggest R&D budgets has one new entry in the top 10: Sanofi. It spent $7.2B last year, knocking out GSK. Which companies out did them? Find out below. ⤵️
https://t.co/Yq670s00is

[BSMHFT NHS Mental Health @bsmhft]

We are pleased to announce that following an internal process @paddynhs, Executive Director for Strategy, People and Partnerships has been appointed as BSMHFT’s Deputy Chief Executive.

We hope you'll all join us in congratulating Patrick! 👏 🎉

[Vega Shah @dr_alphalyrae]

Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains | Nature Microbiology https://t.co/nEZUh9wIc0

[Tansu Yegen @TansuYegen]

Advices to keep the good employees

[Yuh-Line Niou @yuhline]

Everyone in my generation can attest that AOL Instant Messaging (aka AIM) was the best and most revolutionary and most game changing thing we ever experienced. And we loved it. So so much.