Today, I successfully defended my Doctoral Thesis titled, "Understanding how #breastmilk composition alters neonatal #immune trajectory and susceptibility to acute #respiratory tract #infections". 🍾
1/n
🚨 Thrilled to share our new paper out in @ImmunityCP!!!
We uncover a surprising, previously unrecognised role for alveolar macrophages (AMs)—long viewed as the lung’s steady sentinels—during allergic type 2 inflammation.
🧵 below 👇
https://t.co/20CxwiJ6HB
Analysis of data from nearly 1.5 million Danish children suggests that infants hospitalized for #RSV infections have a significantly higher risk of developing asthma when one or both parents are also asthmatic. @bart_lambrecht@BosteelsCedric
https://t.co/pzkGxIdTv8
Excited to share our new paper in @JExpMed ! 🎉
We reveal a key mechanism showing how tissue-resident memory CD8⁺ T cells (Trm) amplify antiviral protection during reinfection.
🧵👇1/6 https://t.co/UQVUQoOKLS
Today, I successfully defended my Doctoral Thesis titled, "Understanding how #breastmilk composition alters neonatal #immune trajectory and susceptibility to acute #respiratory tract #infections". 🍾
Happy to share our latest paper on DC ontogeny! https://t.co/xmz07wMzk3
Congratulations to the team and to Dr Zhaoyuan Liu from the Shanghai Institute of Immunology!
Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabUCSF and @themis_brown, and our own (now in @Nature https://t.co/GS46XE91FG), reports that the dietary pTreg program is initiated by RORγt⁺ antigen-presenting cells. /1
Check out our latest work where we built a single cell perturbation atlas of niche cues in inflamed human intestinal organoids. We hope this resource will be of value in generating therapeutic hypotheses to guide diseased epithelium back to homeostasis. https://t.co/Rb7IP2o7un
Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and @YollandaPariso1 🧵 1/ https://t.co/hkxJu2hxGI
A wave of IRF8-dependent Thetis cells impart tolerance to food antigens early in life. Congratulations on the excellent paper! @themis_brown@ScienceMagazine
https://t.co/O6qZ4nKvy4
Excited to share our latest paper! 🎉
A #maternal high-fat diet predisposes to #infant lung disease via increased neutrophil-mediated #IL6 trans-signaling. @CellReports
https://t.co/CuDbKc3XZM
Congratulations to all involved, particularly @TufaelQIMR and @SimonPhipps14! 🏆