Top Tweets for #DNAdamageResponse
New!👣
Targeting the #DNArepair chromatin-modifier protein SMYD3 as a novel epigenetics-based therapy for #gastriccancer
Look here👇
https://t.co/o71dhS8oU4
#DNAdamageresponse
#HomologousRecombination
#PARPinhibitors
Learn how DYRK kinases shape #cancer therapy.
This review shows how DYRK proteins regulate #DNADamageResponse and highlights DYRK inhibitors as promising #PrecisionOncology strategies. @ShandongUni1901
#OpenAccess in #GenesAndDiseases: https://t.co/4QElks4oRP
🎉 Happy to share our work, now published in @CIR_AACR @AACR !
We identified multinucleated giant macrophages in #PDAC, associated with #Hypoxia, #DNADamageResponse and an #Aggressive #TumorMicroenvironment.
🔗https://t.co/G9v4TSPHA9
@Fedemarch2 @RebiPoli
Through extensive classification of a previously deposited cryoEM dataset, a previously unresolved ALC1–nucleosome complex characterized by a more open conformation of ALC1 was identified #DNADamageResponse #ChromatinRemodeling #ALC1 https://t.co/fiq9QK5IWy
Excited to share our paper, now out in @JCellBiol!🎉
Co-led with George Galea at @embl , we uncover a new layer of spatiotemporal regulation of the #DNADamageResponse between the Golgi and the #Nucleus, revealing an active role of the #Golgi in #DNArepair.
https://t.co/asgxfU0y54
Continuing our discussion with Prof. Robert van Waardenburg, we dive deeper into a crucial warning for modern oncology: Beware the single-omics trap! 🧬
What is your take on mechanistic vs. observational data? 🔬
#Oncology #Topoisomerase #DNADamageResponse #DDR #CryoEM #TME
T-3 days until we land in Honolulu for the Society for Neuro-Oncology (SNO) Annual Meeting, November 19–23. We’ll be presenting two posters on November 21. See you there!
#SNO2025 #neurooncology #DrugDiscovery #DNAdamageResponse #AI #RKV
Casein kinase 2 inhibitor, TBB (perhaps CX-4945 as well), as a novel #Senolytic
Screening of 80 chemicals related #DNADamageResponse on Zmpste24−/− MEF
TBB quenches DDR in senescent cells▶️
⏫unrepaired DNA damage
⏫Apoptosis
TBB, supplied in drinking water
extends lifespan (18->24 wk)
⏫trabecular bone vol
⏬trabecular separation
⏬#CellularSenescence in kidney spleen
unaltered body weight/size
in Zmpste24−/−🐭
Cell Death Dis 2024 @cddpress
https://t.co/gP14NpoJ7F
Forging New Pathways In The Fight Against Cancer - @DrOrenGilad Ph.D. - CEO, Aprea Therapeutics @ProgressPotent1 #Cancer #Oncology #TumorBiology #OrenGilad #ApreaTherapeutics #Biotechnology #DrugDevelopment #Macrocycles #SyntheticLethality #DNADamageResponse #ATRKinase #WEE1 #Doylestown #Philadelphia #BRCA #PARP #ProgressPotentialAndPossibilities #IraPastor #Podcast #STEM #Innovation #Technology #Science #Research https://t.co/7XlWPCdseu
Incorporating DNA Damage Response (DDR) Mechanisms in Cancer Systems: 2nd Edition. Submissions are welcome.
#DNAdamage #DNADamageresponse #DDR
https://t.co/kiyG4fLTJr
New issue online!🍹
Functionally-instructed modifiers of response to ATR inhibition in experimental #glioma
Full text⤵️
https://t.co/Yg91HiDemH
#DNAdamageresponse
#Functionalgenomics
🌄Viewpoint🌄
🔗Dimerization choice & alternative functions of ZBTB transcription factors🔗
✍️@BatuErman et al explore molecular mechanisms that potentially diversify the function of ZBTB proteins @UniBogazici
➡️https://t.co/vKl43YzpEm
#DNAdamageresponse #ICFSyndrome #OpenAccess
Inspiring lecture by Fabrizio d’Adda Di Fagagna @FdAdF66 on #DNAdamageresponse and #aging at #RuijinHospital
Looking forward to present my work today at #SINS2023 during the Parallel Symposia “Cutting-edge approaches for the study of #neurodevelopment and related disorders” 🧠
#brain #organoids #dnadamageresponse
Hasterok et al. discover that the #AndrogenReceptor does not directly regulate the transcription of #DNADamageResponse genes in #ProstateCancer.
https://t.co/IThJR7f3se
@DanielFrigo @UVA @UConn @MDAndersonNews @UHouston
📰 Mutations and Biomarkers of DNA Damage in Myeloma
👨🎓 Joshua Galloway, Cole Petrilla, Ruchi Kudalkar, et al.
🔗 https://t.co/mDUsAL3s5d
@AjHematology @ASH_hematology
#multiplemyeloma #DNAdamageresponse #DNArepair
🌱🔬 Unveil the gene network in response to DNA damage in Arabidopsis in this latest RNAseq processed dataset! See how DREM was used to reveal distinct functions and regulatory features. #DNADamageResponse #GeneRegulation #ArabidopsisResearch
▶️OSD 498: https://t.co/MDj0muSmRF
🧠State of the Art Review🧠
DNA damage response in #neurodevelopment and #neuromaintenance
By Zhao-Qi Wang and colleagues from @LeibnizFLI
#DNAdamageresponse #neuralprogenitors
➡�� Read the article free at https://t.co/q1CNP2nsxO #OpenAccess
Check out our newest #collab with @IvanAhelLab and @JgmRack on serine #ADPribosylation in the #drosophila #dnadamageresponse out in @NatureComms now 🤗
I'm so happy to finally share with you our latest research revealing how ADP-ribosylation controls the DNA damage response in Drosophila! 🪰🧬
Thanks to the fantastic team!
@IvanAhelLab @thenielsenlab @osamuriosamu @DrAntonioAriza @Dunn_School
https://t.co/rqGwLKLK72
Exciting news! Swalife Biotech has been recognized as the "Most Innovative DNA Damage Response Company 2023" at the 8th annual International Life Science Awards.
#Innovation #SOSV #DHPSP #NPMND #INPST #CancerResearch #DNADamageResponse #Personalisedmedicine
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