Top Tweets for #Filovirus
I continua la progressió de #Marburg, encara en rampa de detecció, a #Etiopia. Ja serien 122 els casos possibles (en investigació), amb 12 casos confirmats i 8 morts. Si dintre d'una setmana encara continuem sumant, tindrem un problema evident. #OneHealth #filovirus
Més casos confirmats (10), més morts (5), més casos probables en seguiment (per sobre 50). En aquestes etapes inicials de qualsevol #brot, l'increment es deu a vigilància i detecció. Encara som en rampa. #Marburg #Etiòpia #transmissió
El brot de #Marburg, un patogen #GP4 a #Etiopia continua creixent. 46 casos possibles amb 8 de confirmats i 4 morts. No hi ha cap vaccí comercial però si alguns d'experimentals. Queda per veure si sera aprovat el seu ús d'emergència i arribaran a temps. #filovirus #OneHealth
@WHOUganda @WHO We were honoured to co-host this important #filovirus laboratory training with @WHO, bringing together experts from 18 high-risk countries. Strengthening regional laboratory capacity is key to enhancing preparedness, surveillance, and response to future outbreaks.
Darrer infectat de #ebola a #RDC surt de l'hospital. Per darrera, 64 casos (53 confirmats, 11 probables) amb 45 morts. S'ha vaccinat a més de 35.000 persones. Cap cas nou dsd fa gairebé un mes. Comença el compte enrere de 42 dies. #VaccinesWork #filovirus https://t.co/cV9S6R2bri
.@WHO and @UVRIug have co-hosted a weeklong #filovirus laboratory training for laboratory focal points targeting 18 filovirus high-risk countries to strengthen research & development readiness ahead of potential outbreaks. Under the WHO Emergency Preparedness and Response programme, participants have been trained on standard operating procedures for molecular and immunology techniques. The selected countries for training are Angola, Burundi, Congo, Cote d’Ivoire, DRC, Gabon, Ghana, Guinea, Kenya, Liberia, Mali, Nigeria, Rwanda, Senegal, Sierra-Leone, South Sudan, Tanzania, and Uganda. @WHOAFRO @MinofHealthUG
This afternoon @WHO in collaboration with @MinofHealthUG, @WFP_Uganda @WFP @MSF @AfricaCDC @IDIMakerere @uni_tue concluded a weeklong full scale simulation exercise at Jinja regional referral hospital aimed at enhancing case management during #filovirus outbreaks. The simulation exercise, under the #INITIATE project was supported by @eu_echo @WHOAFRO @EUinUG
🦠"Human Viruses of Major Concern" at #WSV2025
Prof. #Andrea_Marzi (@NIH (@NIAIDNews ), USA) unpacked groundbreaking research on #filovirus pathogenesis and countermeasures.
WSV is honored by her #voluntary #self-funded participation, a testament to his dedication to science
#marburghemorrhagicfever #MHF #marburgvirus nosocomial transmission has occured frequently during outbreaks of #filovirus #hemorrhagicfever in endemic areas
Dia que passa, casos que es sumen (+5). Preocupant i molt lluny de l'estabilització. Tercer brot registrat, ja, si ens referim a la seva magnitud. I només portem 10 dies aprox. des de la declaració oficial. #Marburg #filovirus #transmissio
Com prediem. En poc més d'una setmana hem passat de 26 casos coneguts amb 8 defuncions a un total de 41 casos amb 12 morts, amb forta afectació al personal sanitari. No sembla que el #brot de #Marburg a #Ruanda hagi arribat a l'altiplà d'estabilització, encara. #filovirus
Amakuru mashya | Update
Virusi ya Marburg - 04.10.2024
Both #Marburg and #Ebola are members of the #Filovirus family and have glycosylated #Spike proteins with conserved disulfide bridges. These pathogens do not have the Pam-3-Cys lipid protein toxins. #Allicin in #AllicinV destroys the disulfide bridge functionality of the spike proteins in these viruses.
We recommend #AllicinV shielding for #Marburg as well as 200mcg selenium for a male, and 100mcg for a female daily. We also recommend Chaga mushroom when infected. Allicin will break the GP1 & Gp2 Spike proteins of Marburg while Selenium and Chaga will slow protein translation kinetics down. There are conserved Cysteines in the GP1 and GP2 #Spike proteins of Marburg virus that make conserved #Disulfide bridges that create structure tied to receptor binding and fusion of the virus. Specifically Cysteine 53 (C53) in GP1 forms a disulfide bond with Cysteine 609 (C609) in GP2, linking the two subunits (cited below). Cys85 and Cys511 – Form a conserved disulfide bond in GP1, helping stabilize the receptor-binding domain. Cysteine 601 and Cysteine 670 are conserved within GP2 and form intra-subunit disulfide bridges that maintain the structural integrity of GP2 during the fusion process.
Ten years ago, the world faced the largest #Ebola outbreak in history. Today, we're battling another #filovirus outbreak—#Marburg in #Rwanda.
Read my latest in @PLOSGPH on lessons from the 2014 Ebola outbreak and the critical need for stronger pandemic preparedness, published just before this major #MarburgVirus outbreak was declared last week.
https://t.co/Yd3mti2emS
si finalment les dues persones resulten positives a #Marburg (recordeu, altra ciutat alemanya) la probabilitat que hagin generat transmissions secundaries la considero molt baixa. #filovirus #transmissió Tot comença a Alemanya, però. https://t.co/3nzcj6SAWX
È stato il primo #filovirus scoperto in seguito a focolai in Germania e Jugoslavia nel 1967 correlato all'importazione di cercopitechi verdi africani dall'Uganda. 3/
Casos de #Marburg en 7 dels 30 districtes del país vol dir brot disseminat i moltes cadenes hipotetiques de transmissió difícils de seguir. #filovirus #OneHealth https://t.co/dPGGLIwsZ0
Actualització... 2 mort més, deixant el compte en 8, i 18 infectats aïllats, en observació. #Marburg #transmissió #Ruanda Més important que el comptatge de morts serà la tendència de nous infectats els propers dies. Si la rampa és lenta o inexistent, acabaríem aquí. #filovirus
Per cert, que de primeres estem en una trentena de casos augura un brot intens i probablement perllongat. #Marbug #filovirus #Ruanda
"Unspecific" and "undetected" són qualificatius molt preocupants per un virus de febres hemorràgiques com és #Marburg. #filovirus
⚠️BREAKING:
Rwanda 🇷🇼 reports an unspecified number of Marburg cases in "health facilities", suggesting undetected community spread of the virus in the country.
New collaborative work examining electrostatic interactions between the Ebola virus matrix protein VP40 and the plasma membrane at key arginine substitutions!
https://t.co/7FYQ3G2PcP
#ebola #lipidtime #VP40 #membrane #filovirus
Researchers @pennvet show that the Hippo pathway regulates Ebola virus transcription and particle release
The findings suggest that manipulating the #Hippo pathway could offer new strategies for combating #Ebola
#virology #filovirus
https://t.co/9vot6JdQ0Z
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