Top Tweets for #IntestinalStemCell
#Treg-derived IFNγ and #IL10 synergistically activate #mTORC1 and Myc pathways to promote epithelial repair, with combined #cytokine signaling supporting #IntestinalStemCell growth after therapy-induced #GutInjury. @FischerRIOLab @HendrikPoeck
#STTT: https://t.co/tbFLXJcMGh
🔎 Led by Dr. Jianlou Niu and collaborators, researchers identified an epithelial niche-derived FGF1 that regulated #IntestinalStemCell commitment toward goblet cells, shedding light on strategies for treating #IBD. | @NatureComms
🔓 https://t.co/UPKXWxv3pv
I've been away from X for some time, but I'm very happy to share that we just got a paper out describing how a network of bHLH transcription factors simultaneously regulates #Drosophila #IntestinalStemCell self-renewal and bipotential differentiation
https://t.co/2in3Ye1guh
🔓#OpenAccess "Large animal models enhance the study of crypt-mediated epithelial recovery from prolonged #IntestinalIschemiaReperfusionInjury" by @CMcKAguirreDVM et al.
https://t.co/J7I1aDNFLM
@GonzalezLiara #IntestinalStemCell
Epithelial Zonation of small intestine
scRNAseq
5 (instead of 3) zones▶️Nutrient metabolism
3 Lgr5+#IntestinalStemCell populations▶️a Hoxb7/8/9+ subset
ChEA3+SCENIC▶️transcrptional control of intestinal domains
@RKZwick @OphirKlein @NatureCellBio 2024
https://t.co/OAZ2J08Bzc
📃Antibiotic-induced microbial depletion enhances murine small intestinal epithelial growth in a serotonin-dependent manner by Pooja S. Salvi (@poojashahmd)et al.
https://t.co/8lmmieAhWy
#CellProliferation #IntestinalEpithelium #IntestinalStemCell #AntiBacterialAgents
Let's learn about how mechanosensing could regulate adult #StemCells and tissue growth. 💡
Researchers show that shear stress sensing regulates #IntestinalStemCell proliferation and epithelial cell number in adult #Drosophila. 🐝 @ScienceAdvances
🔖 https://t.co/bHk9jqBnk3
New in @ajpgi: #Antibiotic-induced microbial depletion enhances murine small intestinal #epithelial growth in a serotonin-dependent manner (Salvi et al.)
https://t.co/G6KbnFmxLr
@YaleGenetics @YaleSurgery #CellProliferation #IntestinalStemCell #Anti-BacterialAgents
🥳 We're closing in on our #TopTweet countdown!
If you missed it the first time, check out this study by the @shaleklab from @MIT on demonstrating how to identify modulators of #IntestinalStemCell differentiation!
Congratulations on 2nd Place! 🥈
https://t.co/REGZcdWe1F
The @ShalekLab at @MIT shows that modulators of #IntestinalStemCell differentiation can be identified via multiplexed phenotypic screening using thousands of miniaturized #organoid models of intestinal stem cell differentiation into #PanethCells. 🧫
🔗 https://t.co/j37nZd0dqY
The @ShalekLab at @MIT shows that modulators of #IntestinalStemCell differentiation can be identified via multiplexed phenotypic screening using thousands of miniaturized #organoid models of intestinal stem cell differentiation into #PanethCells. 🧫
🔗 https://t.co/j37nZd0dqY
New research reveals that Lepr+ #mesenchymal cells are important mediators linking systemic diet changes to local #IntestinalStemCell function and might serve as a novel therapeutic target for gut diseases.
📘 @cell_res | 🔗 https://t.co/FE17eYQrkn
Heat‐stable enterotoxin inhibits intestinal stem cell expansion to disrupt the intestinal integrity by downregulating the Wnt/β‐catenin pathway
#Enteroid #IntestinalStemCell #Spheroids #STp https://t.co/ti6q7T7r6S
Using a novel screening method, investigators identified novel transcription factors that regulated the #IntestinalStemCell fate upon endoplasmic reticulum stress.
Full article in @SciReports:
https://t.co/d659RnOhoa
Only 1 week until #CDDW2021 kick-off. I’m excited for the #intestinalstemcell session I put together with @KarpowiczLab
Featured in the round up: A team led by @LickertHeiko at @HelmholtzMunich has identified a specific #IntestinalStemCell niche signaling pathway that regulates intestinal stem cell self-renewal and lineage decisions. https://t.co/VEPNheKDrA
In this review, scientists summarize recent advances in understanding the correlation between Hippo 🦛–YAP signaling and intestinal homeostasis, repair, and tumorigenesis, focusing specifically on #IntestinalStemCell regulation.
https://t.co/tlpXlsLmBG
New in @Cell_Metabolism | Mitochondria define #IntestinalStemCell differentiation downstream of a FOXO/Notch Axis. https://t.co/fnkYX5Xhzq
Congratulations 🎆 to @MariaRodrColman, @mcludikhuize, @Maaikemrl, @MadelonMaurice and colleagues!
Thanks for including us in this nice collection together with @FaranakFattahi @TheSpenceLab @chat_pedsgi - it will be a good introduction for folks new to the field and a useful reference for #intestinalstemcell veterans
A wonderful visual representation of adult stem cell division in intestinal crypts by @HansClevers. #intestinalstemcell #stemcell #Lgr5 #clever
Two PhD students, Hugo Snippert and Laurens van der Flier, took Nick Barker's lineage tracing of Lgr5 crypt #stemcells to a next, multicolor level using their #Confetti mouse We saw no asymmetric divisions Neutrally competing stem cells just divide and push others out of the way
Investigators from École Polytechnique Fédérale de Lausanne (@EPFL) studied the role of bile acids and G protein-coupled bile acid receptor 1 in intestinal renewal, and regulation of #IntestinalStemCell function in mice and #IntestinalOrganoids. https://t.co/b8Qt4VwKtU
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