🚨Another big win for #precisionmedicine
🚨👉🏼Today the FDA approved lirafugratinib for FGFR2‑rearranged cholangiocarcinoma.
⭐️I still remember the first patient in the universe we enrolled on the trial during the peak of the pandemic. Three days in - I called the amazing Ben- the then CMO of @Relay_Tx
“Your drug is working, working too good. We need to work on the right dosing & get it right for patients. I think this baby will graduate someday.” That day is today 🙌🏼 Thankful to all patients who volunteered & the amazing teams that got this to finish line 🙏🏽 !!! @OncoAlert@oncodaily@OncBrothers@ElizSMcKenna@matthewherper@curecc@Aiims1742@MiteshBorad@AliSchram
👉🏼Link to FDA approval https://t.co/8WTjhiTD98
👉🏼Link to @CD_AACR@AACR bench to bedside publication https://t.co/HeME5d8mRZ
Nineteen years ago, I joined Dana-Farber—with a little more hair and far fewer meetings!
I’m deeply grateful to the patients who trusted me and to the colleagues, trainees, and teams who made this journey so meaningful. What a privilege—and what a ride!
In 1948, Sidney Farber and colleagues published his work in @NEJM that helped open the door to modern chemotherapy.
Seeing that history from the same institution — especially after a remarkable #ASCO26 with major plenary contributions and @NEJM papers from @DanaFarber — is humbling.
A powerful reminder that progress in oncology is built across generations: by patients, scientists, clinicians, and teams who keep asking what might be possible.
Detecting lung cancer 5 years before it happens, in @CellCellPress courtesy of the @CharlesSwanton group.
Astonishing translational work !
https://t.co/EvUmIGVLgs
True pleasure to meet with many established & rising Arab oncologists, researchers, postdocs, or residents especially from Jordan and Lebanon at the King Hussein Cancer Center @KHCFKHCC health exchange forums in #ASCO2026@AUB_Lebanon
🚨⭐️Wow! What a surprise!
⭐️Deeply honored to receive the Indo-American-Cancer-Association Award at @ASCO#ASCO26 for Outstanding Contributions to Drug Development & Pioneering Advances in Clinical Cancer Research 2026
👉This recognition means so much not just as a personal milestone, but as a reflection of the incredible VILLAGE that makes this work possible
🙏 Mentors who shaped MY thinking + collaborators who challenged & inspired me + Patients who trusted me with their care + friends & family who anchored me through it all
🙏Thank you to the IACA @IACAconnect leadership for this honor @DrSwami_Iyer@Santchawla1 Vinay Jain @jamecancerdoc@BrainTumorDoc@SewantiLimaye #PrecisionOncology🙏 #ASCO26 #IACA #DrugDevelopment #CancerResearch @OncoAlert@oncodaily@OpenMedicineHQ
This is not just a doubling of survival.
It is the strong signal of a treatment revolution that could reshape pancreatic cancer care, and perhaps many other cancers driven by RAS… @ASCO#asco26@OncoAlert@OpenMedicineHQ@marklewismd
It was a honor to have the chance to discuss 4 tremendous oral presentations on novel ADCs at #ASCO26.
They tell a clear story: TOPO1 ADCs will soon join the treatment arsenal of SCLC, NEC and GYN cancers.
Many challenges ahead, though. The most key: biomarkers and sequencing.
For @ASCO aficionados, there have been questions as to how many standing ovations we have seen. The first I saw was adjuvant Herceptin in 2005. ChatGPT generated the list below for me when prompted for ASCO presentations with standing ovations.