Adrian Janiszewski

Bioinformatician @ SOPHiA Genetics.

[Martina Balli @BalliMartina]

Happy to share our recent publication about conventional IVF, where we reviewed strengths and weaknesses of one of the most practiced assisted reproductive technology (ART) approaches used worldwide.

https://t.co/WASlQZxs1B

#ivf #science #reproduction #fertilitytreatment

[zack chiang @z_chiang]

Confused by all the "what is epigenetics" discourse?

Well I have just the thing for you -- presenting the Epigenetics Alignment Chart!

[Irene Talon @IreneTalon]

🎉 Happy to share our study, now out in @NatureCellBio!

This is the result of an amazing collaboration of our lab @vincentpasque (@KU_Leuven) with @RuggGunnLab (@BabrahamInst), @hendrik_marks (@Radboud_Uni) & @MaartenDhaenens (@ugent).

A 🧵… [1/19]
https://t.co/SVcilliVjj

[Martina Balli @BalliMartina]

On May 8th, I was at work and it happened to be Mother’s Day. I started the day thinking: “Today we have the chance of making new Moms”. I don’t know if it was the positive energy but all our patients of that day became pregnant🤰🏻

This work will never stop to amaze me ✨

[Felix Dietlein @FelixDietlein]

Excited to share our latest work in @ScienceMagazine
(https://t.co/kJFsJEIf0S). Building on the foundational work of the PCAWG and HMF consortia, we established a compendium of mutation events in somatic whole-genome sequencing data of 3,949 patients from 19 tumor types.

[Jasper Janssens @JasperJanssens7]

Our paper describing gene regulation in the fly brain is out now in @Nature! So proud of this one and of the amazing team work with @SaraAibar @ibrahimihsan and @joynismail in the @steinaerts lab! Check it out here https://t.co/gkFcgDtLKX with below our main findings:

[Adrian Janiszewski @janiszewski_a]

@GeorgolG @jeffvierstra @NatureComms Congrats Grigorios! A beautiful piece of work! :)

[Plath Lab @PlathLab]

Excited to share our latest publication out @CellCellPress where we explore how Xist nucleates local protein gradients to propagate gene silencing during X chromosome inactivation. 1/15
https://t.co/Vb76VV443N
🧫🧬🔬🧵

[Adrian Janiszewski @janiszewski_a]

Make sure to check it out and see how we leveraged single-cell allele-resolution RNA-seq and bulk ATAC-seq to better understand X chromosome dosage compensation!

[Adrian Janiszewski @janiszewski_a]

Excited to share that our latest study: “Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals” is out in @GenomeBiology!

[Genome Biology @GenomeBiology]

Study of chromatin accessibility on the X chromosome in embryonic fibroblasts and during reprogramming, from @irenetalon, @janiszewski_a, @vincentpasque & co. ATAC-seq shows the active X has more accessible chromatin than autosomes, reversed during reprog https://t.co/935xF6oY7u

[Adrian Janiszewski @janiszewski_a]

It's been an amazing team effort with @IreneTalon, @vincentpasque and all collaborators who helped us immensely.

[Alex Cagan @ATJCagan]

Thrilled to share our paper on the mutational landscape of human somatic and germline cells @Nature. We integrated histology and genomics to explore the genetic diversity that develops within our bodies as we age.
https://t.co/Ep2do4JNXP
An illustrated tweetorial… [1/15]

[Nikolay Oskolkov @NikolayOskolkov]

I have just published Deep Learning on Human Microbiome at Medium / Towards Data Science
https://t.co/YCoXzVstMO

[Jacqueline Severino @jacquelineseve7]

Delighted to share the latest @PayerLab preprint about the implications of #Xchromosome activity on meiotic entry in #mouse primordial germ cells #PGCs in vitro https://t.co/MUTz5IVoa8 1/

[Brockdorff Lab @BrockdorffLab]

Excited to share our work published in @ScienceMagazine led by our DPhil @LisaRodermund, jointly supervised by @LSchermelleh and us. (1/3) https://t.co/LixbI55guN

[LluisLab 🏳️‍🌈 @lab_lluis]

Very excited to share with you our pre-print linking Wnt deregulation with carboplatin resistance in Breast Cancer! @willyaaoliveira @DevReg_KULeuven @scil_leuven #Wntpathway
https://t.co/9vX2PsAbKo

[Adrian Janiszewski @janiszewski_a]

Thanks to everyone who contributed; @vincentpasque, @GeorgolG, @lab_lluis, @BalliMartina, @PAthanasouli, @embojournal and a very helpful editor.

[Adrian Janiszewski @janiszewski_a]

In our recent News & Views article in The EMBO Journal @embojournal we introduced and discussed very interesting new findings from the Joerg Betschinger group @FMIscience who identified chromatin regulators that restrict the developmental potential of mouse embryonic stem cells.

[Adrian Janiszewski @janiszewski_a]

Check out our EMBO News&Views “Keep the fate: how chromatin regulators safeguard embryonic stem cell identity“ here: https://t.co/USgPm3nN8Q 
and the discussed article published in the EMBO journal: https://t.co/lwVNNIIbov

[Edda Schulz @EddaGSchulz]

How can genes decode information with a defined logic? In our new @biorxivpreprint led by @RutgerGjaltema and @TSchwammle we dissect the regulatory landscape of Xist and find a distal-proximal hierarchy that generates a logical AND-gate. https://t.co/zfjKIIsRkq A thread