Jennifer Herrmann

PhD student in Genomic Medicine and Statistics @UniofOxford @MRC_WIMM interested in #generegulation and the #cellcycle | she/her | all views are my own

[MRC WIMM @MRC_WIMM]

Congratulations to Lauren (@l_cmurphy), Patrick, Jennifer (@jenniherrmann), and Anna, who have been shortlisted for the Ita Askonas Medal 🏅 and will give talks at #WIMMday2023 for the chance to win a prize of £500! 🎉

[MRC WIMM @MRC_WIMM]

Our second session is off to a flying start with a deep dive into gene regulation in the cell cycle delivered by @jenniherrmann

Co-supervised by @jrmmhughes (@FoldingGenome) and @RobBeagrie (@HumanGeneticsOx)

[Takashi Fukaya @FukayaLab]

How do distal enhancers control transcription dynamics in living cells? Check out our latest work published in @MolecularCell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. https://t.co/vpOSWJAfBq

[Jennifer Herrmann @jenniherrmann]

It's great to see the project I worked on for my Master's Thesis at @KU_Leuven out as a preprint. Congrats to everyone who has been involved in this work!

[Jennifer Herrmann @jenniherrmann]

Giving a talk and discussing my work on transcriptional regulation of genes throughout the cell cycle at @KeystoneSymp #KSChromatin23 was such a cool experience. Really grateful to have had this opportunity!

[Jennifer Herrmann @jenniherrmann]

@RobBeagrie *downloads paper and stores it in citation manager* - yep, that’ll do.

[Marina Marchenko @marchkotik]

Thank you all the participants! It was very nice and productive time with guys at #EMBODevTempo !
Definitely catch up with you soon!❤️

[Jennifer Herrmann @jenniherrmann]

@KateMurnane8 @Epithemiou Few people know this but I moved to the UK specifically to enjoy delicacies like this.

[James Davies @jojdavies]

Really excited to share our latest paper... fantastic collaboration with @MariekeOudelaar where we developed tiled Micro Capture-C to generate Hi-C like plots at 20bp resolution.
Turns out there are nanoscale TADs inside enhancers!
https://t.co/hHIWnQFLnM

[Jennifer Herrmann @jenniherrmann]

We also discuss how studying the #cellcycle (a prime example of how being “basic” can be cool) can help us better understand how enhancers function. Looking forward to hearing what you think!

[Jennifer Herrmann @jenniherrmann]

Just out in @TrendsGenetics: @jrmmhughes, @RobBeagrie and I have written a review on #enhancers, their interactions and their role in cellular #differentiation. https://t.co/EdOgvkDBgL

[Jennifer Herrmann @jenniherrmann]

We address how enhancer activity and enhancer-promoter interactions are linked to cell type-specific #transcription, and how they are promoted or constrained by different factors in the #regulatorygenome.

[Hughes Group @FoldingGenome]

Working with @jdavieslab we have identified the likely gene at 3p21.31 responsible for increased risk of COVID-19 respiratory failure. Published in @NatureGenet today!

https://t.co/YcYcx72Mow

[Broad Institute @broadinstitute]

Scientists are identifying characteristics that might make some rare cancer cells, called cycling persister cells, resistant to drug treatment. The results could help researchers design therapies to delay or ultimately prevent disease recurrence. https://t.co/TqcOYxa2oJ

[UCL Laboratory for Molecular Cell Biology @LMCB_UCL]

A recent publication in @CurrentBiology examines asymmetric nuclear division in Drosophila neural stem cells and finds that the daughter nuclei differ in chromatin organisation, envelope composition and size.
@Roubinet31 @EM__Ian @lab_baum
https://t.co/gQJlBha6QI

[Hughes Group @FoldingGenome]

Delighted to see @andrewjohnking et al.'s characterization of primitive alpha globin regulation come out in @NatureComms today. Including a beautiful example of what you can do with @jojdavies new MCC method (described in @nature last month).

https://t.co/9ZWiW4eqI9

[Hughes Group @FoldingGenome]

Our latest paper (in @NatureComms) characterises a mongenic anemia causing variant. We show how it creates a de novo promoter that acts as an enhancer-blocker.
#3Dgenome #generegulation

https://t.co/0vpS9Eqtql

[James Davies @jojdavies]

Delighted to share my lab’s @jdavieslab first big paper in @Nature!

We’ve developed a new 3C technique called Micro Capture-C that can generate base pair resolution 3C data https://t.co/Mgr26d2bTE

[Loyal Goff @loyalgoff]

Pleased to present 'tricycle', a new R package for rapid, accurate, and scalable estimation of cell cycle position for scRNA-Seq using transfer learning. A joint project from our lab and the lab of @KasperDHansen. https://t.co/X5wWCvoy4c

[Emma Lundberg @Prof_Lundberg]

Very proud to present our work "Spatiotemporal dissection of the cell cycle with single-cell proteogenomics” in @nature today. A great (and long) team effort led by @Diana_Mahdesian @AnthonyCesnik, w @ProteinAtlas. A thread... #cellatlas #cellcycle https://t.co/KhH0jrtBBf