Max Fottner

Postdoc in the @klanglab at ETH Zurich. Trying to shed light on the ubiquitin system using chemical biology.

[Cell Chemical Biology @CellChemBiol]

Peptide passports: Programmable import fuels novel protein building blocks https://t.co/xM9yYLu0LH

[David Sinclair @davidasinclair]

New paper today in @ScienceMagazine shows Nudix hydrolase 5 protein binds adenosine, making some people sensitive to some chemo drugs. Maybe it binds NAD too, and this could desensitize patients to the toxicity
https://t.co/OWHZwMPncO

[nature @Nature]

Nature research paper: Hijacking a bacterial ABC transporter for genetic code expansion

https://t.co/jsHLBvmjzb

[Kathrin Lang @klanglab]

Happy that this is finally online!
Genetic code expansion approaches to decipher the ubiquitin code @ACSChemRev
Many congratulations to Vera, Max and Marco!
@VeraWanka @MaxFottner @MarkoCigler 🥂🎉🥳

https://t.co/Y5oZ89bKgv

[Satpal Virdee @SatpalVirdee]

Thank you @GCEcenter @klang @AChemSynBio for the opportunity to share our work and hear what's happening with genetic code expansion at #GCE2024. And what a finish to the evening! 😎

[Max Fottner @MaxFottner]

@SatpalVirdee @GCEcenter @KLang @AChemSynBio You are as precise as your Ub probes when it comes to darts unfortunately (but could still improve on tagging @klanglab) 🫣 That one still haunts me 🎯 Officially requesting a Revanche 😬

[Marko Cigler @MarkoCigler]

Proud to see our 'detective story' on uncovering the MoA of Orpinolide published in its final form in @nchembio! Immensely grateful to @georg_e_winter, the Waldmann lab @mpimoph and @laraialab for being part of this fantastic collaboration!

[Daniela Danková @DankovaDaniela]

I'm happy to share our News & Views article featured in @NatureChemistry, highlighting the excellent work on site-specific incorporation of glutarylated and succinylated lysine residues into multidomain proteins via genetic code expansion by @klanglab!

https://t.co/QzpQ2zaURy

[Maximilian Gantz @MaxGantz_]

Check out our new paper @NatureChemistry where we use microfluidics to identify a mini enzyme from a de novo designed library giving a plausible scenario for emergence of enzymatic function at #OriginOfLife by #DirectedEvolution!

https://t.co/6865tEhgVJ

[Kathrin Lang @klanglab]

Very excited to co-organize GCE2024 with @AChemSynBio and @Mehl_lab at @GCEcenter!
Come to Corvallis, Oregon to hear about the newest in genetic code expansion! We have a stellar speaker lineup from academia and industry!👇
Retweet and register!

https://t.co/g881i8cSks

[Maximilian Gantz @MaxGantz_]

Biocatalysts make chemical industry more sustainable but engineering enzymes is too slow! Check out our preprint @hollfelderlab where we show how microfluidics & AI can help: We rapidly sequence-function profile an IRED in microdroplets and use AI to accelerate its engineering⚡️

[Kathrin Lang @klanglab]

Genetically encoding negatively charged lysine PTMs succinylation/glutarylation and studying their funcional roles! Great team effort by first authors @ML_Jokisch and @Maria_Weyh! Congrats @Maria_Weyh @ML_Jokisch @MaxFottner and Anh! 🥳🤩🙌👨‍🔬🧑‍🔬 @klanglab
https://t.co/CKzQi1lavS

[Maximilian Gantz @MaxGantz_]

Check out our latest preprint @hollfelderlab presenting a versatile cascade for enzyme screening in microfluidic droplets! We hope coupled assay like this will make microfluidics more accessible reducing cost and speeding up sustainable biocatalyst discovery timelines 🌱⏰

[Kathrin Lang @klanglab]

We have a new doctor in the @klanglab! Well done to Kristina - Dr. Krauskopf - who successfully defended her thesis!🎓🥳👏 Many thanks to @SieberLab and Hubert Gasteiger for being on the committee at TUM! Very sorry for only being present via Zoom and missing the party fun 🤒🦠🙄

[Stephan Hacker (inactive account) @StephanHacker2]

Amazing virtual talk by @klanglab at #ESBOC56 @ESBOC_Gregynog. She talked about her group's work on expanding the functions of proteins with non-canonical amino acids. Great applications in bioconjugations, crosslinking and defined ubiquitin conjugates. https://t.co/W7rSdLSEJi

[Sebastian Pomplun @PomplunSeb]

I am looking for a #Postdoc!
Do you have #molecular_biology experience and are excited about developing top edge #drug_discovery modalities in a young team https://t.co/CxRthShr86?

Join us @LACDR @LeidenScience

Please RT!

https://t.co/WfQIsFeXZc

[Sebastian Pomplun @PomplunSeb]

@ERC_Research funded #postdoc position in my group
We are looking for a molecular biologist excited to help developing synthetic tools that can control gene transcription.
@UniLeiden @LACDR @LeidenScience
Please RT!!! And apply :-)

https://t.co/PknjqpvePp

[Kathrin Lang @klanglab]

Check out our new paper for site-specific labeling proteins and building defined Ub/Ubl-protein conjugates using a plant Asp-endopeptidase.
Great effort by @MaxFottner @jhmgrtnr @MaxGantz_ @RaMue1304 and @NkTimon! Congratulations to all!👩‍🔬👨‍🔬🤩🙌🥳

[J. Am. Chem. Soc. @J_A_C_S]

Site-Specific Protein Labeling & Generation of Defined Ubiquitin-Protein Conjugates Using an Asparaginyl Endopeptidase @ETH_DCHAB @ETH_en @klanglab @TU_Muenchen @MaxFottner #SiteSpecific #ProteinLabelling #Ubiquitin #Conjugates #Asparaginyl #Endopeptidase https://t.co/lk6jeZArM9

[D-CHAB @ETH_DCHAB]

Sometimes we must create artificial things to understand nature. Kathrin Lang @klanglab, new professor of #ChemicalBiology #LOC, develops special tools and enables deep insights into complex biological systems. Learn more on June 1 #inaugurallecture & on https://t.co/TPZS7TWEkN