Maria del Pilar Miranda

Postdoctoral fellow interested in mitochondrial biology. Opinions are my own.

[Oliver Hahn @Oliver__Hahn]

🚨 Postdoc position in my lab @calico is live!
I'm looking for someone deeply curious about the aging brain🧠⌛️, who wants to build novel scientific projects from scratch and carry them to publication and, ideally, into their own lab🥼🧪. No neuroscience background needed.

[Vamsi Mootha @VamsiMootha]

Excited to share our new paper led by Josh Meisel w/ Gary Ruvkun. Worm suppressor genetics + biochemistry reveal that balance of frataxin and FDX2 levels is key for Fe–S cluster synthesis. Lowering FDX2 alleviates frataxin deficiency in multiple models.
https://t.co/D50ivZjM6i

[Melissa Walker @MWalkerMDPhD]

Single case > new insights. Increased perfusion BEFORE other MRI changes during a MELAS stroke-like episode + ictal-interictal continuum during symptomatic period.
@AltenBaris @nsanar Cat Chu @MGHNeurology @MghPediNeuro
https://t.co/PcaeMV2tqH

[Vamsi Mootha @VamsiMootha]

Hypoxia in a pill!

Chronic, continuous 11% FIO2 suppresses brain pathology in models of mitochondrial disease and aging, but we need practical alternatives. We combine a Hb "left-shifter" with a HIF2a inhibitor to achieve therapeutic hypoxia in mice.

https://t.co/6sX9kieRPV

[Natalia Ocampo-Peñuela, PhD @birdmapper]

Continuing with #COP16Cali today I learned a lot about Green Cities 🌳 🏙️ including from my high school friend who is now an amazing landscape architect @anamirandave #CasaHumboldt

[Maria del Pilar Miranda @mpilarmirandav]

@DeshwalSoni Congratulations!!

[Maria del Pilar Miranda @mpilarmirandav]

@apatgir @NIH @ninds @EmoryUniversity @PharmChemBio @EmoryMedicine @Mito_News @Mito_Therapy @MitoResearch @cure_mito @MitOtalks @UMDF Congratulations Anupam!

[Maria del Pilar Miranda @mpilarmirandav]

@sahola6 Congratulations Sofia!!

[Maria del Pilar Miranda @mpilarmirandav]

@sahola6 @IMSR_UoB @unibirmingham Congratulations!!!

[Nils-Göran Larsson @mitopinionated]

New review to read:
DOI: 10.1146/annurev-biochem-052621-092014

[Maria del Pilar Miranda @mpilarmirandav]

@ErikMcshane Congratulations Erik!

[Alexis A. Jourdain @jourdainlab]

Our lab is looking for 143B "rho0" cells (no mtDNA) 👀.

Would anyone agree to send us some?

[Maria del Pilar Miranda @mpilarmirandav]

Very happy to see this out as a preprint! Huge thanks to all coauthors.

[Inge Kühl @IngeKuhl]

@biorxivpreprint What happens when you overexpress POLRMT in different tissues? Preview our data on bioRxiv; Big thanks to all authors @mpilarmirandav, @mitopinionated , @FilipovskaLab , @BioDynaMit_Lab

[Vamsi Mootha @VamsiMootha]

Hypoxia rescue (& hyperoxia sensitivity) of mito CI mutants is evolutionary conserved! Harnessing the power of worm genetics, Josh Meisel w/ ⁦⁦⁦@gary_ruvkun⁩ discovers “hypoxia mimetic” and “hypoxia resistant” mutants, yielding key mechanisms. https://t.co/h2CVsAFsGW

[Vamsi Mootha @VamsiMootha]

Delighted to share new study by Tslil Ast now @WeizmannScience w/ Y. Itoh, D. Suess, @A_Amunts showing (1) the Fe-S proteome is destabilized w/frataxin loss, (2) mitoribosome assembly factor METTL17 harbors a 4Fe-4S cluster, serving as an Fe-S checkpoint for mito translation.

[WredenbergLab @WredenbergLab]

If you’re a fan of metabolism, mitochondria and their role in disease mechanisms, we have a great opportunity to work with us in Stockholm. We are looking for an enthusiastic PostDoc to join our group in @MolMet_KI at Karolinska Institutet. @mitojobs

https://t.co/bnnwJIi0f1

[Payam A. Gammage @mito_oncogene]

Hey #sciencetwitter #mito #cancer ppl - pls RT - we've got two posts open in @mito_oncogene lab @CRUK_BI @UofGCancerSci for postdoc fellows! One computational one wet lab - something for everyone :) check out https://t.co/Qy34IEDPWf & https://t.co/UUqMYo1gAV for more info. 👍🙂

[Valentin F. Cracan @VFCracan]

My lab is seeking a postdoctoral fellow in genetically encoded sensors and tools for studying the role of redox imbalance in cancer, neurodegeneration and aging @jobRxiv @mitojobs @ScienceCareers https://t.co/2AQoufDScL

[Maria del Pilar Miranda @mpilarmirandav]

Super recommended!!

[Anupam Patgiri, PhD @apatgir]

My lab @EmoryUniversity is seeking a postdoctoral fellow in mitochondrial biology and metabolism. Please RT! @jobRxiv @mitojobs @ScienceCareers @UMDF @Cell_Metabolism @asmsnews

[Anupam Patgiri, PhD @apatgir]

My lab @EmoryUniversity is seeking a postdoctoral fellow in mitochondrial biology and metabolism. Please RT! @jobRxiv @mitojobs @ScienceCareers @UMDF @Cell_Metabolism @asmsnews