Benthos Prime Central

Specialists in omics, RNA biology & extracellular vesicles 🧬
Science-backed consulting for industry & academia 🔬
CEO: @prabhu_gene | 🌐

[Benthos Prime Central @mybenthos]

Explore how we turn complex data into actionable insights.

🌐https://t.co/uDULmK071t
Led by @Prabhu_gene

#BenthosPrimeCentral #MultiOmics #ExosomeResearch #PrecisionMedicine #DataDrivenBiology

[Prabhu Mathiyalagan @Prabhu_gene]

🚨 2 days left!

🧬 Decoding #GWAS Variants: From Signals to Function

💡 Turn GWAS peaks into biological insight with #CRISPR, iPSC & functional #genomics.

📅 July 2 | 12 PM ET
🎙️ @rovingscientist
🔗 Register: https://t.co/owisHrfpFL

Powered by @mybenthos

[Prabhu Mathiyalagan @Prabhu_gene]

🧬 GWASmeRNA™ Live Experience
Hosted by @mybenthos

Decode RNA-genomic connections & uncover how SNPs may act via RNA—not just DNA/proteins.

📅 June 25 (11 AM CET🇪🇺)
📅 June 26 (2 PM ET🇺🇸)

👇 Details & registration in the thread

#GWAS #Epitranscriptomics #RNAtools

[Prabhu Mathiyalagan @Prabhu_gene]

🧬 Scientific consulting that actually moves your science forward.

At @mybenthos, we’ve worked with labs, startups & R&D teams across the globe.

Sometimes you don’t need another experiment — you need a second brain.

[Circulation Research @CircRes]

Check out the latest review in the June 6th issue of @CircRes by Orlowski & colleagues "Intracellular #pH Regulation in Ventricular Myocytes: Implications for #Cardiac Health and Disease" at https://t.co/hEtW2zitOC

[Mustafa Özdoğan, MD @ozdogan_md]

🚨 Exercise is no longer optional, it is essential!

One of the most impactful studies at #ASCO25

🏃‍♂️ The #CHALLENGE trial (LBA4319) proves that structured exercise after chemo in stage III colon cancer is not just lifestyle—it’s life-saving.

📊 5y DFS: 80.3% vs 73.9%
❤️ 8y OS: 90.3% vs 83.2%
📉 Mortality risk ↓ by 37%

📄 Simultaneously in @NEJM https://t.co/y4e9u71OLI

#ColorectalCancer #OncoTwitter #ExerciseOncology #exercise

[Kyle Tretina, Ph.D. @AllThingsApx]

If you're following AI-driven drug discovery, you should read this paper below.

Generative AI just advanced a first-in-class TNIK blocker for pulmonary fibrosis, rentosertib, through phase 2a.

[David R. Liu @davidrliu]

Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab.
1/13
https://t.co/ZLHtZm5Gmw

[Jens Hjerling Leffler ⭐️⭐️🇺🇦⬜️🟥⬜️ @HjerlingLeffler]

Postdoc positions available in my lab @karolinskainst - exciting science and fantastic environment. I take mentoring seriously - 7/7 postdocs that left my lab has faculty positions today. Existing datasets and funds to build new ones available. https://t.co/fGgDwbpC2j

[Vivek Subbiah, MD @VivekSubbiah]

🚨 Wow! #ASCO25 @ASCO was absolutely massive!
10 @NEJM papers published simultaneously 👉 all practice-changing studies ! 🔬✨🧵 See below for these studies 👇@oncoalert

[Benthos Prime Central @mybenthos]

🚨 Hot off the press in Nature Communications!

Engineered extracellular vesicles (EVs) achieve >40% genome editing in hippocampal cells after a single dose 🤯

🔗 https://t.co/Gc1nrmK24f

👏 Huge congrats to @Samir_ELA_lab & team!

[Nikon Microscope Solutions @NikonInst]

🔬🧬 New expansion in situ genome sequencing uses #SuperResolution expansion #Microscopy #ExM to localize genomic DNA and nuclear proteins, applied to linking lamin abnormalities in progeria-derived fibroblasts with areas of aberrant chromatin repression: https://t.co/cygBjf5kZl

[Frank J. Slack, PhD @irmdirector]

Don’t forget to tune TOMORROW, Tuesday, June 3 at 3 PM EST to hear Armon Sharei, PhD from Portal Bio

“A Silicon Membrane-based Platform for Multiplexed RNA Delivery and Cell Engineering of Primary Cells”

To register click this link: https://t.co/9SVvu2kvL1

#RNA #RNAMedicine

[Benthos Prime Central @mybenthos]

🧠 Huge leap in spatial genomics!

gsMap by @liyang_song & @jyang1981 maps complex traits like schizophrenia onto the brain's spatial cell structureusing ST + GWAS.

Must-read: https://t.co/HdBQ47670Y

#Genomics #SpatialOmics

[Benthos Prime Central @mybenthos]

What if #RNAstructure mattered more than sequence?

That shift is here — in RNA therapeutics, folding, accessibility & mods like m⁶A are shaping smarter design.

We’re building tools to make that possible.

Is RNA structure underused in drug design?

[nature @Nature]

Nature research paper: Programmable control of spatial transcriptome in live cells and neurons

https://t.co/tpy0DXbTdW

[Veera Rajagopal  @doctorveera]

Mechanisms through which synonymous mutations can affect gene expression

Zhang & Qian Nat Rev Gen
https://t.co/LWPnLIp2qZ

[Circulation Research @CircRes]

@CircRes Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases
Liao et al Research Letter "Heart-Brain Crosstalk in #MI: Role of Heart #EVs in Neuroinflammation" https://t.co/Fbx8jLztS9
@MarbanLab @JankauskasPhD

[Miriam Merad, MD, PhD @MiriamMerad]

Revoking J1 visas is not only cruel, it undermines trust in American science. As we wrote with Jan Vilcek, an immigrant whose work led to one of medicine’s biggest breakthroughs, J1 students fuel discovery, innovation & US economic growth. https://t.co/RKjSnkwl3k

[Hossein Ardehali @ArdehaliHossein]

We are hiring! The Ardehali lab at @UAZHeart and @UAZMedTucson is hiring postdocs and technicians. Our research focuses on metabolism, Immunology, iron biology and cardiovascular disease. Interested applicants can contact me directly.

[Student Network on EVs @SNEVresearch]

🚨Tomorrow!🚨

Join us to hear Dr. Peinado (@hps2002) and learn about how tumour-derived sEVs shape the pre-metastatic niche and their potential as biomarkers and therapeutic targets.

🕒TimeZone: https://t.co/ryTq3jwsp8 🎯Join the SNEV network: https://t.co/aUsM2l1BlT