Parikshit S Sharma, MD, MPH, FACC, FHRS

Associate Professor, Section Chief of Cardiac Electrophysiology; Cleveland Clinic Florida

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

His Bundle pacing for CRT
https://t.co/6rLH4Fh3GD. @Hisdoc1 @gopi_gdanda1 @KennethEllenbo1 @jaykoneru @DrRoderickTung @gauravaupadhyay

[Penn Electrophysiology Fellowship @PennEPFellows]

Another masterclass series at #IFP conference w/@BIOTRONIK_US in Philadelphia with Drs. Frank Marchlinski , John Miller, @DavidCallans @DrFerminGarcia @rdschaller @True_EP @LuigiDiBiaseMD @psharmadoc @KeepInRhythm and others. #Epeeps, see you all next year!

[Radcliffe Cardiology @radcliffeCARDIO]

🎙️NEW #AHA23 Interview 💫Dr Pugazhendhi Vijayaraman discusses the findings of the I-CLAS study on left bundle branch area pacing.

📽️Watch here👉 https://t.co/fJdKt6n8Up

📊Results suggest that left-bundle branch pacing reduced the risk and time to occurrence of ventricular tachycardia and ventricular fibrillation as compared to biventricular pacing.

#CardioTwitter @Hisdoc1

[Bengt Herweg @BengtHerweg]

Happy to see the results of our hard work presented at the #AHA2023 and published in @CircAHA.

Lower incidence of ventricular arrhythmias and new onset atrial fibrillation with LBBAP – A new dimension to conduction system pacing.

Thank you to all collaborators:
@Hisdoc1 @psharmadoc @OscarCan @shunmug_his_mdu @ZanonFrancesco @Marek_Jastrz_EP @JiangangZou @MihailChelu @kvernooy @ZacharyWhinnett @gmnair1 @ManoloMolina8 @karlocurila @dzalavadia23 @Cicely Dye @Sharath C. Vipparthy @RyanBrunetti @Mishalmumtaz_ @drpmoskal @AndrewLeong @AntoniusStipdonk @JerinGeorge @YusufQadeer @JeffreyKolominsky @Mehrdad Golian @MorcosRamez @LinaMarcantoni @FaizSubzposh @KennethEllenbo1 @pugazhendh44472

Arrhythmic Risk In Biventricular Pacing Compared with Left Bundle Branch Area Pacing: Results From The International LBBAP Collaborative Study (I-CLAS) | Circulation:
https://t.co/bSirqjZ1Z4

[Ramez Morcos, M.D. M.B.A @MorcosRamez]

🚀 Exciting news from #AHA2023 @CircAHA

Honored to be part of The International LBBAP Collaborative Study (I-CLAS). The latest large-scale (1,778 patients), multi-center (15 centers) observational study is being presented at the American Heart Association (AHA) conference.

Arrhythmic Risk with BVP vs LBBAP

https://t.co/oxydAWI2GM

Key takeaways:
Reduced Arrhythmias with LBBAP: LBBAP (Left Bundle Branch Area Pacing) showed a lower incidence of both sustained and non-sustained ventricular tachyarrhythmias (4.2%) compared to BVP (Biventricular Pacing) group (9.3%).

Lower Occurrence of Atrial Fibrillation: New onset atrial fibrillation (AF) was less common in patients undergoing LBBAP (2.8%) compared to those with BVP (6.6%).

#Cardiology #LBBAP #Conductionsystempacing #CRT

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

@mbelshazly @rusharrhythmia @RushMedical @Hisdoc1 @avolgman @KennethEllenbo1 @DrRoderickTung @GDandamudiMD @gauravaupadhyay Probably adds an additional 15 mins to the case. Doing it for most cases with atypical LBBB/IVCD to better understand if lateral wall activation is shortened significantly with CSP. If not, just advance the a CS lead over the vision wire for BiV pacing.

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

Exciting work by the Rush EP team!! Excited to share some of this work @ PPS7 Chicago. Hope to see you there!! @rusharrhythmia @RushMedical @Hisdoc1 @avolgman @KennethEllenbo1 @DrRoderickTung @GDandamudiMD @gauravaupadhyay

[Shaojie Chen @ShaojieChen1]

Thoughts 💭:
APAA (As Physiological As Achievable) Principle

Shared Algorithm for Cardiac Resynchronization in Patients With LBBB/IVCD Pattern

Ravi @SharathVippart1 Sanders @hhuang123 Larsen Trohman @Hisdoc1
@psharmadoc

cited https://t.co/nzOUS70661

@JACCJournals @shivkumarmd @C_Meyer_MD
@JonPicciniSr @MaullyShah @utedrow
@drrakeshg1 @EJSMD @DrMarwanRefaat @javadm20 @pjsm83 @mencardio @shemybenchetrit @glckty @gabustillosg @berniann @ugurcanpolatmd @manuelpatete @liviateixeiramd @ACuevaParra @KTamirisaMD @yolyabreuh @MargaridaPujol @rdschaller @DrRoderickTung @MDerndorfer @purerfellner

@Maeskander @drgastonvergara @gautamsand @EugenioCingolan @DaviddlCuevas @wedenskyeffect @drrpathak @LaredoMikael @CSHeartResearch

[Gaurav A. Upadhyay @gauravaupadhyay]

Elegant work by @psharmadoc and the Rush Team! Congratulations!

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

@ShaojieChen1 @SharathVippart1 @hhuang123 @Hisdoc1 @JACCJournals Thanks @yolyabreuh. Strauss is good but not perfect. N except for a coated wire and an extra 10 mins to the case, there are no additional resources needed. If CSP fails to shorten time to lateral wall activation, we use that same lead for implantation in the atrium.

[Roderick Tung @DrRoderickTung]

Do you know how to distinguish left conduction system capture from LV septal capture in LBBAP?

What are the latest trials in LBBAP?

How do I program LBBAP?

What are the limitations of LVAT?

We are less than 2 weeks away from the 7th International Physiology of Pacing Symposium #PPS7 in CHICAGO and we have two more travel scholarships for #EPFellows. Email [email protected] to claim!

[Gaurav A. Upadhyay @gauravaupadhyay]

Seats are still available for #PPS7 on 11/3/23 in Chicago! HRS Synchronicity affiliate with CME available. Register now at https://t.co/5oIjFrCcaN Free for fellows and residents! #EPeeps @HRSonline @Hisdoc1 @drsuneet @VKutyifa @JagSinghMD @psharmadoc

[Zachary Whinnett @ZacharyWhinnett]

Physiology of Pacing meeting. My favourite meeting of the year.

[American College of Cardiology @ACCinTouch]

New state-of-the-art review published in #JACCCEP aims to provide a comprehensive update on recent advances in conduction system pacing.

Read the top points from the review: https://t.co/MI375I84vd #HeartFailure

[curilakarol @curilakarol]

Cardiac Conduction System Pacing: A Comprehensive Update https://t.co/ojfW3Qelqw

[American College of Cardiology @ACCinTouch]

What are the clinical outcomes with biventricular pacing v. left bundle branch area pacing among patients undergoing cardiac resynchronization therapy?

Get the answer in #JACC: https://t.co/mn5LeIj9tV

[Roderick Tung @DrRoderickTung]

#PPS7 in Chicago 11-3-23
Register: https://t.co/rkwiwCXAHc

[Nicolas Clementy @clementy_ep]

Dr Vijayaraman #HRS2023 late breaking trial: #LBBAP vs #CRT.
- controlled non-randomized
- 1,778 patients (!)
- better echo response, better outcomes driven by HF hospitalization reduction
- fewer complications

[Nikhil Shah, MD @NikhilShahMD]

✅LBBAP group with⬇️thresholds vs BiV, fewer w ⬆️threshold post-implant, shorter QRS, ⬇️complications
✅LBBAP w ⬇️1' outcome (death HFH), HR 1.45
✅both groups with ⬆️LVEF, but ⬆️⬆️ in LBBAP group

These are terrific findings and very good news for #LBBAP #HRS2023 #2023PaceSetter

[AnnabelleVolgman MD @avolgman]

So great to reconnect with old friends ⁦@HRSonline⁩ #HRS2023 @PassmanRod⁩ & finally meet ⁦@JonPicciniSr⁩! Great collaborations w/ ⁦@RushMedical⁩ @DukeHeartCenter⁩ & ⁦@NorthwesternMed⁩ on AF trials! ⁦@psharmadoc⁩ ⁦@hhuang123⁩ ⁦

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

#EPeeps @GDandamudiMD @ImperialEP @gauravaupadhyay @MdHuang @ZanonFrancesco @DrRoderickTung @avolgman @Medtronic

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

Packed house at the LBBP HRS symposium in #NOLA @HRS2023 @Hisdoc1 @KennethEllenbo1 @shivkumarmd @shunmug_his_mdu @Marek_Jastrz_EP @rdschaller @ZacharyWhinnett @Dr_JozaEP

[Parikshit S Sharma, MD, MPH, FACC, FHRS @psharmadoc]

Packed house at the LBBP HRS symposium in #NOLA @HRS2023 @Hisdoc1 @KennethEllenbo1 @shivkumarmd @shunmug_his_mdu @Marek_Jastrz_EP @rdschaller @ZacharyWhinnett @Dr_JozaEP