@maxvcg Burn him at the stake!!! Hahaha no seriously some people forget to do QC on RNA seq or don’t consider RT-qPCR have the same bais of using random hexamers for cDNA conversion. All I can say regardless of the assay replication is key 🔑
@maxvcg If you didn’t you might want to add insulators on each side of your construct to fight the silencing. 2X core cHS4 works well and has been widely studied by Gary Felsenfeld
Work with us:
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Work with us on disruptive new ideas to understand, measure, and target aging and cancer.
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Our recent work uncovering the H3K36me2 writer-reader module as a epigenetic vulnerability in H3K27M-DIPG
Thanks all!
@ReinbergDanny@GaryLeRoy3 @placantonakilab @stairway_2devin@rs_meyer @NDescostes
The H3K36me2 writer-reader dependency in H3K27M-DIPG https://t.co/HSlhTJZyEK
This is an important paper!! Dnmt3b3 isoform action might explain why Dnmt3L has a relatively mild embryonic phenotype when it has such a “catastrophic” germline phenotype. Great stuff. https://t.co/CRY8UeYdJd
Thrilled to share that our multi-PI U01 grant with Danwei Huangfu and Christina Leslie got awarded by @4DNucleome!!! #WomenInSTEM rock! Postdocs and students with passion in 3D chromatin, enhancer function and cell fate decisions are needed!!! Please contact me!
Congratulations to Roberto Bonasio, of @PennCDB & @PennEpiInst, on the #MaxPlanckHumboldt2020 award for outstanding work in the field of #epigenetics.
Learn more about Dr. Bonasio & this award 👉https://t.co/v6yuR1lixO
Was fun to contribute to this review led by @AndrewSeeber on new technologies that are shining a new light on chromosome and chromatin research, and what we can learn from these approaches:
https://t.co/LMJF8VGmUs
Gov. Charlie Baker (R-MA) gets emotional when talking about Trump's calls to "dominate" protesters: "When the country needed compassion ... it was simply nowhere to be found.”