I’m happy to share that I will join the LIT in Regensburg (https://t.co/Y6ukzliOWn) as a Group Leader in Structural Biochemistry in May! More updates on Bluesky or LinkedIn 🙂. (This will be my last post here for now.)
This is 🔥🔥🔥!
@MartinPacesa, Lennart Nickel, @befcorreia@sokrypton, et al. developed BindCraft - an open-source pipeline to design de novo binders for basically any protein of interest.
We asked if we could design binders for CbAgo - a DNA-guided DNA interfering Argonaute..
Congratulations to David Baker on receiving the #NobelPrize in #Chemistry! 👏 As a Distinguished Affiliated Professor at our university, the #biochemist is being awarded the prize for his work in the field of computational #proteindesign: https://t.co/sEK02q20xx
📷U.Benz
This year’s #NobelPrize in Chemistry has gone to David Baker “for computational protein design,” and Demis Hassabis and John Jumper “for protein structure prediction.” https://t.co/KYISlA4scj
Excited to join the Gene Center at LMU @GeneCenter_LMU@LMU_Muenchen as a professor, looking forward to design some cool and unusual de novo proteins here!
If you or someone you know is curious about #splicing, the Beusch lab (https://t.co/xz2JrCRzYR) @Uni_WUE is hiring PhD students! Check out the official advertisement here: https://t.co/wF6hQdqwlv - still a chance to apply till Oct 15th!
Here is the link to the Colab, let us know if you have any problems or you have a hard target our pipeline cannot design against! We want to keep improving it and community feedback is very important 🙏🏻💻
https://t.co/TXAvgyQ6Rx
Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. @befcorreia@sokrypton
https://t.co/IPhMFpRgHh
There is a new tool on BioIcons to turn any protein (in PDB format) into a 2D vector illustration in SVG format. You can upload any PDB file or import from PDB, AlphaFoldDB or ESMFoldDB. Feedback welcome :)
https://t.co/grMysO8JV5
Wow, this is really unexpected! Designs were done together with Lennart Nickel in @befcorreia lab. Our pipeline will be fully open source and preprint online hopefully next week 🙂
Wow, this is really unexpected! Designs were done together with Lennart Nickel in @befcorreia lab. Our pipeline will be fully open source and preprint online hopefully next week 🙂
In this new @CIR_AACR study, Drs. @darelmb, @MiglioriniDenis, and team at @unige_en validate PTPRZ1 as a #glioblastoma target and prompt the clinical translation of anti-PTPRZ1 CAR T cells. 🥼
Give it a read: https://t.co/xSg1F7AYBW
IL2 muteins with directed disruption of aggregation sites enable enhanced specificity coupled to improved production capacity @LabListon
https://t.co/QWHWiEAetP
Leman Biotech is excited to announce the successful treatment of the first pediatric patient with an extremely low dose (1%), who achieved complete remission and was discharged without complications. https://t.co/DjvTR1H9tv
The Google Colab version of RFdiffusion with the conditional fold generation option worked well! We successfully placed two helices in the beta barrel structure. The RMSD between prediction and X-ray is only 0.3 Å!
https://t.co/LEkjDJOEnf
https://t.co/QWYdIApu9a