Siddharth Krishnan

•Senior Scientist @QuellTx •Tregs •CART •FACS •Immunology •SciComm, languages, coins, flags, maps, hiking, food-not in that order •Tamil •Views=own🔬🇮🇳🇬🇧

[Siddharth Krishnan @sidnificantdata]

Paper from the post doc on HSPCs in the healthy gingiva finally out in @JExpMed 👇🏽👇🏽👇🏽

[Journal of Experimental Medicine @JExpMed]

Healthy gingiva is a site of extramedullary haematopoiesis. Report from Siddharth Krishnan, Joanne E. Konkel @grainger_konkel and colleagues at @LydiaBeckerIII @FBMH_UoM:
https://t.co/WlV0r0cwT8

#oralimmunity #Mucosalimmunology

[Waggoner Lab @LabWaggoner]

Architecture of the neutrophil compartment @Nature
https://t.co/8UNowJOWAd @ivanbamartin @AndrsHidalgo16 @lai9uan @danielacerezo @Yale 🇨🇳🇪🇸🇺🇸

[Waggoner Lab @LabWaggoner]

Inhibitory PD-1 axis maintains high-avidity stem-like CD8+ T cells @Nature #Germain @NIAIDNews
https://t.co/FfW2mimCg9

[Waggoner Lab @LabWaggoner]

pDCs amplify tissue-resident memory CD8+ T cell responses during viral reinfection @JExpMed
https://t.co/68Nqnh2q4m

[Waggoner Lab @LabWaggoner]

Dynamics and variegation in the Treg response to IL-2
https://t.co/n0jlxxW2DH
@KumbaSeddu @Harvardmed

[Waggoner Lab @LabWaggoner]

iPEX facilitates untargeted spatial proteomics at micrometer resolution for diverse applications
@Nature @ZouYilong 🇨🇳 @Westlake_Uni
https://t.co/x7DnZrsBmp

[The Nobel Prize @NobelPrize]

The Raman effect is the change in the wavelength of light that occurs when a light beam is deflected by molecules. It was named after Sir Chandrasekhara Venkata Raman who was born #OnThisDay, 7 November 1888. The Raman effect is used to analyse different types of material.

[Michael 英泉 Eisen @mbeisen]

If only Rosalind Franklin had pre-printed her image

[IdoAmitLab @IdoAmitLab]

Amazing study by Anne and co. demonstrating the role of PU.1 in maintaining the microglia homeostatic state
https://t.co/EgQyVcsXLt

[Jonathan Kipnis 🟦 @jonykipnis]

Exciting new work from Anne Schaefer’s lab describing new protective microglia biology 👏👏👏 || Lymphoid gene expression supports neuroprotective microglia function | Nature https://t.co/5nb2vm8RxL

[Journal of Experimental Medicine @JExpMed]

Ray, Krummel et al. show that targeting CD206⁺ #macrophages disrupts the establishment of a key antitumor immune axis. https://t.co/PxVgowKKaZ

📘 #cancer #immunotherapy collection: https://t.co/wowDSe1NqS
#SITC25

[Immunity @ImmunityCP]

Online now: Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development https://t.co/r9KmAN3NaB

[Waggoner Lab @LabWaggoner]

Viral vectors displaying peptide-MHC are versatile tools for activating and reprogramming antitumor CD8 T cells directly in vivo @ScienceAdvances @MEBirnbaum @MITdeptofBE @kochinstitute @ragoninstitute
https://t.co/6vhCU0xka7

[Waggoner Lab @LabWaggoner]

Tertiary lymphoid structures in a subset of gliomas that show signs of functional adaptive immune activation and are associated with longer overall patient survival and an immune-permissive tumor microenvironment @ImmunityCP @K_Imkeller 🇩🇪
https://t.co/5goCN0454e

[Waggoner Lab @LabWaggoner]

Balancing IL-17–mediated protection and IFN-γ–driven pathology at mucocutaneous barriers @TrendsImmuno
https://t.co/f597GZfDtV @NIH 🇺🇸

[ICMR @ICMRDELHI]

AdFalci Vax — India’s 1st indigenous multi-stage malaria vaccine 💉🌍 developed by @ICMR_RMRCBBSR
Licensed to industry partners under #PatentMitra .
Innovation ➡️ Impact. @PanaceaBiotec @ZydusUniverse @biological_e @TechinventionL @indimmune_

[Eric Topol @EricTopol]

The billionaires funding aging reversal.
When they were young they wanted to be rich. When they were rich, they wanted to be young.
@shaneshifflett @AmyDMarcus @AlexLJanin
https://t.co/ul8G0Vq5z5

[Matthias Nahrendorf @MatthiasNahrend]

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science https://t.co/FrQryxcsmX

[Idoyaga Lab @Idoyaga_Lab]

Our paper made the September cover of @NatImmunol! 🎉
Aren’t dendritic cells beautiful? 😍
SEM shows pDCs transitioning into cDC2-like cells.
Huge congrats to the whole team! 👏
🔗 https://t.co/fS4aaeajRF

[Waggoner Lab @LabWaggoner]

Supercharged NK cells: a unique population of NK cells capable of differentiating stem cells and lysis of MHC class I high differentiated tumors🇺🇸
https://t.co/HkHKsYGU9U
important work from immigrant scientists 🇮🇳🇹🇼🇮🇷 @UCLA

[Science Magazine @ScienceMagazine]

Dietary saturated fatty acids skew monocytes and macrophages in the lungs toward an inflammatory phenotype and exacerbate airway inflammation in mice, shows a study that decrypts the connection between diet and lung immune cell activation. @ScienceTM https://t.co/xuUSNaM2Te