Dr. Stephanie Kravitz

Computational Biologist at 10X Genomics. Taking the “mess around and find out” approach to life and science very seriously 🧬🔬👩🏻‍💻

[Rajiv McCoy @rajivmccoy]

Our latest study presents open access RNA-seq data from cell lines from 731 people from 26 globally diverse populations, addressing a persistent ancestry bias in our field. We hope this resource enables more equitable advances in personalized medicine. https://t.co/nDRpSX0lKL

[Dr. Stephanie Kravitz @snkravitz]

All poster sessions should be like this ☀️ @10xGenomics San Diego UGM!

[Dr. Stephanie Kravitz @snkravitz]

@aaronquinlan I saw one of these in the wild a couple weeks ago, a guy scooting around the lake. Slowly. I thought it was some kind of homemade contraption (not necessarily surprising here) 🤣

[David Cook @DavidPCook]

Great that we're starting to see some data comparing these platforms head-to-head. And kudos to those making the data public. I think we do a disservice trying to boil the comparison down to a couple summary metrics. Eg. dove into this breast cancer data for an hour 1/n

[Dylan Webster @DylanPWebster]

Want to analyze Seurat data without code? Use the new @10xGenomics LoupeR package to
move your data into the new Loupe 7. It sports a redesigned UI, and includes new features that put publication-ready figures just a few clicks away!

#genomics #singlecell

[Dr. Stephanie Kravitz @snkravitz]

It's been incredible to watch the @10xGenomics team bring this to fruition! Such a gorgeous dataset, I'm excited to see how the science community uses Xenium and the new Mouse Tissue Atlasing Panel to make new discoveries.

[10x Genomics @10xGenomics]

Biology is beautiful—and Xenium proves it by bringing it to life with the new Mouse Tissue Atlasing Panel. Learn how #singlecellspatial imaging can help you uncover the splendor of your sample here: https://t.co/tJ4IBtvlbK

[Bo Wang @BoWang87]

🎉Exciting Update of scGPT 🎉: After receiving significant attention from the community since our April release, we're thrilled to announce the first major update for scGPT - a foundation model for single-cell multi-omic data.

This update integrates community feedback and leverages the latest data release from @cellxgene. It boasts larger pretraining data, and more robust models, and expands the range of application tasks.

Pre-print (V2) available: https://t.co/4aB2c4ZgJy
Access our open-source code and models here: https://t.co/13n0bJvgT2
Detailed tutorials: https://t.co/enNqXqXkdY

Highlights of this update include:

🔬 Introducing the first GPT-style foundation model for single-cell multi-omic data, pretrained on over 33M human cell atlas data.

💡 Our generalist approach enables one model to accomplish multiple tasks in single-cell analysis, including multi-omic integrative analysis and perturbation prediction.

🧬 Discovering gene-gene interactions specific to various conditions using learned attention weights and gene embeddings.

🚀 Uncovered a scaling law showcasing continuous model performance enhancement as data volume increases.

🐾 scGPT model zoo (see github) now offers multiple pre-trained foundation models for various solid organs and a comprehensive pan-cancer model. Begin exploring your data with the most fitting foundation model.

We welcome your thoughts on specialist vs generalist approaches in single-cell studies. Many thanks for the following technical analyses of scGPT:
1. Excellent twittorial by @simocristea: https://t.co/ICq3V78oxG
2. Comprehensive review on LLM in cell biology by @s_batzoglou: https://t.co/xtl5WCXijC
3. Insightful blog by @SalvatoreRaieli: https://t.co/7v8PRv9NNc

Kudos to Haotian (@HAOTIANCUI1) & Chloe (@chloexwang1) for their exemplary work on this project. @VectorInst @pmcc_ai @UHNAIHUB @bradwouters @drbarryrubin @UofT_TCAIREM @UofT_LMP @UofTCompSci @uoftmedicine

[Dr. Stephanie Kravitz @snkravitz]

FurbAI

[jessica card @jessicard]

i hooked up chatgpt to a furby and I think this may be the start of something bad for humanity

[Dr. Stephanie Kravitz @snkravitz]

@laurel_hiatt Congrats!!! 🎉

[10x Genomics @10xGenomics]

This #InternationalWomensDay we highlight a few women here at 10x Genomics who are integral to our success. They told us what drove them to pursue a career in science👇

[Nick Banovich @NeBanovich]

Small piece of an airway from our first real Xenium run. Over 34M transcripts across a 1.5cm^2 region. Not a bad first shot on goal!

@10xGenomics
#spatialtranscriptomics
#spatialbiology

[Dr. Stephanie Kravitz @snkravitz]

Thank you @JulieCKiefer for the great write up of our work! Also gets to show off our cover art submission :) @GreggNeuroLab @aaronquinlan @mikelove

[christopher gregg @GreggNeuroLab]

Nice article from @JulieCKiefer !!! Thank you. Random Allelic Expression of Genes Could Complicate Disease, Diagnosis | University of Utah Health | University of Utah Health https://t.co/3vSMdK19Co

[Dr. Stephanie Kravitz @snkravitz]

@NeBanovich @10xGenomics Thank you! I hear our teams may be collaborating in the near future! :)

[Dr. Stephanie Kravitz @snkravitz]

As for life updates, it has been a whirlwind last few months. In September, I finished my PhD 🎓 In October, I started my dream job with @10xGenomics 🔬 and in Jan I moved to the Bay Area! 🌉 It's all been a bit scary and overwhelming, but I'm grateful to be here for the ride :)

[Dr. Stephanie Kravitz @snkravitz]

I am emerging from my Twitter hiatus with some very exciting life/science updates! 1) The culmination of my thesis work is finally out in @CellReports https://t.co/Y1daHPzKzA

[Alex Cagan @ATJCagan]

Amanda Janesick from @10xGenomics on high resolution mapping of the breast cancer tumor microenvironment using integrated single-cell, spatial and in-situ analysis of FFPE tissue #AGBT23

[Dr. Stephanie Kravitz @snkravitz]

@Ng2Laura Congrats!!!! 🎉 🍾

[Dr. Stephanie Kravitz @snkravitz]

Very cool to hear folks reading my paper for journal club, and hearing ideas on how to advance the work in all sorts of areas!

[christopher gregg @GreggNeuroLab]

Big thank you to all of the colleagues who shared their cool papers and findings on allelic expression and gene noise with me by email after seeing @snkravitz new paper. Please keep them coming. I love seeing your cool science and ideas. https://t.co/zKDITjUI54

[10x Genomics @10xGenomics]

Start exploring our three worlds of research possibilities. Meet us tomorrow morning in Room 216, and follow our live tweets for up-to-the-moment news on AGBT. #AGBT23

[10x Genomics @10xGenomics]

It's poster day! Time to explore three new applications of 10x Genomics. Come to Regency Ballroom 1-3, starting at 1:30! #AGBT23

[Dr. Stephanie Kravitz @snkravitz]

@jprr91 @10xGenomics Very very excited to be here (even if I’m terrible at social media 😄)

[Dr. Stephanie Kravitz @snkravitz]

@mohitsbasnet @CellReports I’m certainly excited to keep watching how the field emerges! Much we have yet to learn and understand

[Dr. Stephanie Kravitz @snkravitz]

I am emerging from my Twitter hiatus with some very exciting life/science updates! 1) The culmination of my thesis work is finally out in @CellReports https://t.co/Y1daHPzKzA