@Alfdoc2@THilalMD I have an analogy where I compare cancer to a city with surrounding towns and travelers who are trying to find new homes. I tie surgeons to cutting out the city, rad onc to nuking the towns, and me (medonc) to poisoning the travelers in hopes they don’t find new homes
#HematologyTweetstory 32: lymph nodes with names. There’s also a major personal announcement in this thread. We each have lots of lymph nodes: an estimated 500-600 (Image: @MayoClinic). Like stars, they cluster. (Did you ever think of your axilla as a lymphatic “galaxy”?)🙂/1
#ASCO22 is only 2 weeks away! Below are my Top 10 abstracts I'm looking forward to in #bcsm across early & metastatic settings.
I've also attached the "why" - what is intriguing me about these particular abstracts or why they are important IMO.
@SarahCannonDocs@OncoAlert
APHINITY: Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive #breastcancer
"Age per se is not a reason either to prescribe more aggressive therapies or to expect a different treatment benefit" ~IDFS for age ≤40 or >40
@JNCI_Now@OncoAlert
https://t.co/i1mCk2TFkr
Great talk by my colleague and co-mentor @RoschewskiMD from @NCICCR_Lymphoma on a novel trial with Acala window in 1L DLBCL. Responses to BTKi across all COO and LymphGEN subtypes with ctDNA showing an early indicator of radiographic response #ASH21#lymphoma
EBCTCG analysis of taxane with and w/o anthracycline. 15% relative reduction and 2.5% absolute reduction in invasive recurrence for A+T vs T. Larger reduction with concurrent schedules.
@OncoAlert#SABCS2021#bcsm
Breaking news: Triplet therapy with Darolutamide + Docetaxel + ADT improves OS compared to docetaxel + ADT in men with mCSPC #ProstateCancer👉Significantly improved OS, the primary endpoint. Another position triplet Rx trial after Peace-1. @OncoAlert@urotoday
I lost my mentor. Pat Carlson, who as a rheum study coordinator hired me at 17 yo when I came from rural small town, who signed me up for mcat, who gave me $ for apps when I couldn’t afford secondaries, cried on my wedding and divorce day. 1/2
Free Self Paced on-line @NIH#Pharmacology course
#pharmacology is very complicated, but necessary for many aspects of #medicine & #research
Learn from a course directed by 2 of the best: Drs. Cordes & Figg @WilliamFigg1
#MedTwitter
Link: https://t.co/kI97dPiif1…
@Dr_RShatsky I just bombarded your inbox but if I could like your comments a million times I would. Unless you’ve lived it, you don’t get it. I bit my tongue many times when it came up. Luckily I have worked in very supportive environments
Very happy to see the FDA approval of adjuvant atezolizumab in patients with resected PD-L1+ early stage NSCLC. So excited to have been a part of the practice changing IMpower010 trial! Making a difference in the lives of NSCLC patients! #LCSM
Abemaciclib + endocrine therapy for early breast cancer was approved by @FDAOncology based on the monarchE study.
Results of the the primary outcome analysis presented at the #ESMOVirtualPlenary are available #openaccess in @Annals_Oncology https://t.co/I5kFGN3NBJ #bcsm
Who are the patients who will benefit the most from abemaciclib in adjuvant ET? What is the optimum duration for CDK 4/6 inhibitors? @dradityabardia@matteolambe@kevinpunie@myESMO @prat_aleix