timisstuck

Executive Editor at Life Science Alliance: with even less Musk:

[timisstuck @timisstuck]

Writing about negative data was fun because I read a bunch of Stephen Jay Gould, plus a related commentary by Howard Bowerman.

Both provided fantastic examples outside cell biology and biomedicine that perfectly highlight the universality of this issue:

[timisstuck @timisstuck]

@OdedRechavi Yes!

This was formally demonstrated in 2023 in the field of catalysis research:
https://t.co/xZSgcj8dwU

[Anshul Kundaje @anshulkundaje]

Every perspective piece of "virtual cells" consistently ignores cis regulation. You can mark my words. No truly biologically causal "virtual cell" without learning how DNA, RNA & proteins directly mediate gene regulation. 6/

[Steven Strogatz @stevenstrogatz]

A book and a letter that changed my life. After I read The Geometry of Biological Time, I wrote to its author and asked if I could come work with him. His reply, scrawled in his characteristic magic marker, led to his becoming my most important mentor.

[LifeScienceAlliance @LSAjournal]

“Publishing our previous papers in LSA has enhanced their reach, fostered interdisciplinary engagement, and increased impact.”— Carsten Gram Hansen @gram_lab. Publish in LSA, where scientific excellence sets the standard: https://t.co/MILBebf0Ss

[LifeScienceAlliance @LSAjournal]

In our LSA Immunology Collection:
TRPM7 and magnesium coordinate the activation and differentiation of human CD4 T-cells. #Immunology #Biology
https://t.co/muT1T3PoGL

[Daniel Litt @littmath]

can’t believe people are complaining my paper is wrong. did you even read the “Limitations” section, where I wrote “This paper is wrong.”?????

[timisstuck @timisstuck]

As an editor who gladly publishes purely descriptive papers (including atlases) 🙋‍♂️

[Arjun Raj @arjunrajlab]

Can someone start a journal called “Cell Atlases” so that the rest of the journals can go back to publishing interesting things?

[timisstuck @timisstuck]

Spent a delightful week visiting my colleagues @EMBOPress and attending the super stimulating @EMBLEvents symposium on phase separation in cell biology.

Everything an editor wants in one place 🥰

[timisstuck @timisstuck]

As an editor who reads 1000s of manuscripts: yes

[eigenrobot @eigenrobot]

asking people to read ai-generated text is offensive.

this is not because ai text is intrinsically bad. rather, the author has not paid a cost to write the text himself. this cost is a credible signal he finds its communication important.

so: not paying that cost is telling

[timisstuck @timisstuck]

Read here: https://t.co/r6f7uCdGCd

[timisstuck @timisstuck]

Core facilities are at the center of research integrity and reproducibility efforts: they are the experts helping researchers get their stuff done!

Now out in @JofMicroscopy this excellently argued perspective coauthored by my colleague @RockefellerUniv Alison North.

[timisstuck @timisstuck]

“Nature-level” “nature-style” …

Nature journal’s branding is so powerful that just making your plots appear like theirs is sold as a benefit.

And I don’t think Nature enforces a specific style for plots anyway??

[Vincent Logic | 信号＞噪音 @VincentLogic]

发现个科研绘图神器！

nature-skills，用 matplotlib 就能画出 Nature 级别的图。多面板布局、配色、字体、排版都给你整得明明白白，直接输出可编辑的 SVG。

内置了 5 套 Nature 风格的示例模板，支持柱状图、折线图、热图、散点图、雷达图等 10 种图表类型。再也不用画完图再丢 AI 里重绘了。

搞科研写论文的，这个能省不少事儿，画出来的图直接能投稿。

项目地址放评论区了👇

[timisstuck @timisstuck]

Editors are absolutely not scrutinizing images by eye and just "missed" this. Certainly not at Cell Press!

This kind of image duplication is trivial to detect with very standard QC checks. Why would the journal let this issue go uncorrected?

[Richard Fuisz @richardfuisz]

This paper got a few million views across various RTs two weeks ago: EMF remote-controlled mice...

Look carefully at the saline & control images from the paper -- can you see how the two images are flipped and re-cropped? h/t @AndrewGYork and friends for the close read

[timisstuck @timisstuck]

The focus on a banchmarking/competition of AI ~against~ human advisors is helpful for measuring what they can do.

But this is emphasized much more strongly than what David mentioned... and lay readers only reasonable take away is that AI will fully replace doctors.

[timisstuck @timisstuck]

This paper was mentioned by Eric Horvitz, Microsoft CSO (and coauthor of this paper) yesterday at Rockefeller.

His takeaway was o-1 ~integration~ with physicians as advisors. Humans in the loop.

Yet that isn't mentioned in the abstract nor the Editor Summary @ScienceMagazine

[Eric Topol @EricTopol]

New @ScienceMagazine
The o-1 reasoning model (text only, from @OpenAI, released, Sept 2024) exceeded performance cf GPT-4 and physicians for clinical vignette management reasoning and in a real-world emergency department assessment for initial triage @AdamRodmanMD @PeterBrodeurMD @arjunmanrai @jonc101x
https://t.co/tPZqZAE8cd

[timisstuck @timisstuck]

The biggest innovation in vaccines in recent years (mRNA) actually sidesteps the very cells that we are all taught are essential for vaccines to work.

[Miriam Merad, MD, PhD @MiriamMerad]

Big takeaway: cellular expression patterns matter. mRNA expression in hepatocytes and myocytes shapes the immune response. Surprisingly, direct expression in DCs is not required—antigen can be transferred to them. Important implications for mRNA vaccine and drug design. (2/3)

[timisstuck @timisstuck]

@Eric_Betzig 💀💀💀

[timisstuck @timisstuck]

BATF3 is involved in memory T cell differentiation. Here the authors take a deep dive into its potential promoting CAR T cell functions. They profile epigenetic rewiring and provide detailed comparisons with the related BATF.

Congrats to the authors on this impressive study!

[LifeScienceAlliance @LSAjournal]

Check out a new paper published in LSA:
BATF3 regulates differentiation of CD8+ T lymphocytes and memory differentiation program
@NagoyaUniv https://t.co/ewJZzYzatF

[American Society for Cell Biology @ASCBiology]

Abstract submissions for Cell Bio 2026 are now open

Share your latest research with the global cell biology community & connect with peers from around the world. Submit by June 9 for full consideration. Late-breaking abstracts are accepted through Aug 4.

https://t.co/YVHFYkBspa

[Rockefeller U. Press @RockUPress]

Hello Boston! We're looking forward to meeting everyone at IMMUNOLOGY2026 #AAI2026! Stop by 📍Booth 1018 anytime to chat about our journals and pick up a copy of the @JExpMed Immunology collection magazine and a souvenir!