ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY. Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out today in @Nature!
https://t.co/i9bGl2Vq40
@JungmannLab@MPI_Biochem
Our article on a flexible, graph-driven algorithm for DNA sequencing-based microscopy is out now in @nanoscale_rsc: https://t.co/9RREbrxD8B
Work lead by @scilifelab/@KTHuniversity
PhD student David Fernandez Bonet.
native nanodiscs!
Determination of oligomeric organization of membrane proteins from native membranes at nanoscale-spatial and single-molecule resolution https://t.co/ab58f4wElk
The spatial distribution and placement of antigens in nanoparticle-based cancer vaccines can substantially affect antigen processing, cytokine production, the induction of immune memory and tumour growth.
https://t.co/SwXERDtfRy
As vaccines and boosters for #COVID19 are distributed, we look back at this data visualization from 2017 that shows the power of vaccines to vanquish disease—an impact that far eclipses their minute risks. #ScienceMagArchives
Learn more: https://t.co/iRy12vd9Qw @NewsfromScience
Synthetic circuits that program new capabilities into human cells have tremendous potential to expand emerging gene and cell-based therapies. Our latest work, out today in @ScienceMagazine, reports a platform to accelerate these developments: (1/n)
https://t.co/YUORpuHuZ0
Check out our paper @ScienceMagazine. We engineered synthetic T cell circuits that locally produce the cytokine IL2. Specific configurations of IL2 circuits dramatically improved T cell clearance of solid tumors without systemic toxicity. @CDI_UCSF#SynBio https://t.co/qiZmB8IYXb
A Phase 1 clinical trial provides promising results for a broadly neutralizing antibody #HIV vaccine, according to a new study in Science.
Learn more ⬇️
📄: https://t.co/HgvKfJX7Pf
#SciencePerspective: https://t.co/cEqev89IwA
Our December issue is now live! On the cover, proximity sequencing combines proximity ligation and sequencing to quantify proteins, complexes and mRNAs in single cells. Credit: Second Bay Studios @SavasTay_UChi
Paper: https://t.co/nBg2DiT5a5
Issue: https://t.co/Q0uYggCnt9
Proximity sequencing for simultaneous measurement of proteins, protein complexes and mRNA in single cells, finally published in @naturemethods !
https://t.co/czdWla6LzB