Postdoctoral fellow in the Maze Lab at the Ichan School of Medicine at Mount Sinai studying neuro-epigenetics. Alumnus of @CmuScience and @jhupharmacology.
Very excited to share a new review with @themazelab, born out of my PhD work! 🧠🧬
We dive into how early life experiences shape the epigenetic landscape of the developing brain—and how these lasting changes may contribute to risk for affective disorders.
Check out our new Review manuscript focused on the impact of early life experiences/adversity on the neural epigenome and the contributions of such phenomena to affective disorder risk. This Review was spearheaded by @ANeurogirl, an amazing former PhD student in our lab!
WHaloForce enables chemigenetic imaging of molecular tension in living cells and animals. A wonderful collaboration with Shaohe Wang at HHMI Janelia. https://t.co/IHzx2gj1cZ
DEADLINE | SEPT. 1st! Senior #Postdocs in all fields of #Neuroscience are encouraged to apply for an INCREDIBLE OPPORTUNITY to present your research at #MSNseminars, visit @IcahnMountSinai & meet w/ faculty/trainees! APPLY HERE👉 https://t.co/050Vbd05bF or use QR code on flyer!
NEW STUDY! @IcahnMountSinai's Yuan Cheng, @wuzhengherbert, et al. provide the first mouse model of leader-follower teamwork & link it to specific patterns of prefrontal cortex activity at the level of single cells. Learn More | Full Text @Nature ➡️ https://t.co/j9dwwEK9D7
✨After emerging from an international field of semifinalists announced in May 2025, Mount Sinai’s NYC-Vita Clinical Trial Team was selected as a Milestone 2 Award recipient, advancing to the @xprize Healthspan Finals. Huge Congratulations🎉Learn More 👉 https://t.co/rCbL8CPmhF
'Exercise as a regulator of glymphatic function'
by James Broatch, Nicholas Saner, Melinda Jackson, Warda Syeda, David Bishop & Amy Brodtmann
https://t.co/jfjhqK37yJ
NIH announced this week that K awards will no longer support 'independent clinical trial required', the pathway by which clinicians become independent clinical trialists. See @ScienceMagazine https://t.co/Bs0DT9k7zK
🎉CONGRATULATIONS to Drs. Dina Iathzil Vázquez Carrillo, Brian Kipp & @BenjaminWeekley for being chosen as co-chairs for the MSN-Seminar series 2026-27! #MSNseminars invites leading postdocs to give an institutional seminar & meet w/ @icahnmountsinai's neuroscience community.👏
Happy to share the lab's new work characterizing the impact of a youth-associated protein on microglial function. Congrats to 1st author Brittany Hemmer, w/ excellent contributions f/ @philippi_sarah and all co-authors!
@IcahnMountSinai@SinaiBrain
Paper: https://t.co/aoSEgjomN4
The brain's immune cells are increasingly recognized as key players in #Alzheimers but exactly how they change as disease develops has remained unclear. NEW STUDY by @hoondy, Panos Roussos , et al. provides most comprehensive map to date of these cells. 👉 https://t.co/FZvAA8yGfY
Today in @NatureBiotech we report OptiPrime, a mechanism-based machine learning model for predicting prime editing (PE) efficiencies and suggesting pegRNAs to achieve a user-specified edit. OptiPrime incorporates biochemical knowledge about PE into its mathematical structure, enabling training on ~300,000 PE efficiencies collected using 40 experimental conditions in multiple labs, and outcome predictions of PE variants such as twin prime editing not used in its training. OptiPrime enabled the rapid identification of efficient PE strategies across a variety of applications in vitro and in vivo, and could outperform months or years of manual experimental optimization.
Try out OptiPrime here: https://t.co/ahQPQ9MjYW
PDF: https://t.co/0xHQa5og0f
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Identifying a subtype of brain microglia immune cells that become more abundant during progression to Alzheimer's disease, trying to protect the brain. Extensive work from over 1,600 brain donors, 830,000 immune cell transcriptomes, and experimental models
@NatureGenet
https://t.co/uevfCHiuU4
See this new publication by Susan Yim, Freddyson Martinez-Rivera, and others in @molpsychiatry that describes the role played by the transcription factor E2F3a in nucleus accumbens in the lasting actions of cocaine. @SinaiBrain https://t.co/0Ckzkor8f2