A breathtaking, painting-like composite image of the Messier 17 nebula, showcasing vast clouds of gas and dust illuminated by radiant young stars.
(Credit: ESO/R. Chini)
In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity.
Learn more in a new #SciencePerspective: https://t.co/Vv42SiBcif
Differential geometry uses calculus to study curved spaces and shapes. curvatures In machine learning, it helps us understand the complex, curved "loss landscapes" of neural networks, leading to better optimization algorithms. It's also the basis of information geometry, which analyzes the space of probability distributions. Its most famous real-life application is Einstein's theory of general relativity, which models gravity as the curvature of spacetime, a core concept from the field.
Image Source: https://t.co/lILYFtgkfb
Astronomers have, for the first time ever, obtained a radio image of two supermassive black holes orbiting each other at the core of the quasar OJ287.
This pair, locked in a twelve-year orbital dance some 5 billion light-years away, had long been hypothesized based on periodic fluctuations in the quasar’s brightness.
What makes the new observation remarkable is that the two black holes are resolved separately in the radio image, each identified through its intense jets of particles, even though the black holes themselves remain invisible.
The scientists achieved this with an array combining Earth-based radio telescopes and the RadioAstron space telescope, whose orbital baseline extended roughly halfway to the Moon.
This configuration boosted the resolution to a level about 100,000 times sharper than typical optical images, making the separation of the two emission sources possible.
In the captured image, the smaller black hole’s jet exhibits a distinctive “twisting” or “wagging” motion, suggested to result from its orbital movement around its more massive companion, thus providing a dynamic glimpse into the behavior of the system.
By comparing the observed emission to theoretical predictions, researchers confirmed the black holes appeared exactly where the models had long forecast them to be.
Although the team notes some caveats, such as possible overlap of the jets, which future higher-resolution observations might resolve, the current result represents a major milestone, offering the first visual confirmation that dual supermassive black holes really do orbit one another.
👉 https://t.co/mTDyjohzSL
There is a fascinating connection between infinity and fractals, which are geometric shapes that have self-similarity at different scales. For example, the Mandelbrot set is a fractal that is defined by a simple formula, but it has an infinitely complex boundary that contains copies of itself at smaller and smaller scales. The area of the Mandelbrot set is finite, but its perimeter is infinite.
Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new Science study.
The findings advance our understanding of the relationship between aging and the risk of pathologies including neurodegenerative disease. https://t.co/2Xvp0c3ftg
Fast forward billions of years, and witness the awe-inspiring spectacle as Andromeda and the Milky Way collide in a celestial dance.
(Credit: NASA; ESA; Z. Levay and R. van der Marel, STScI; T. Hallas, and A. Mellinger)
For the first time in four decades, a new algorithm has improved upon the speed limit for calculating the fastest route between two points. @benbenbrubaker reports: https://t.co/6aSLdzXVEO
The gut-brain axis is a bidirectional communication network between the gastrointestinal tract and the central nervous system. This dynamic system integrates neural, endocrine, immune, and metabolic signals, many of which are modulated by the gut microbiota.
🧠 1. Neural Pathway
The vagus nerve and enteric nervous system (ENS) transmit afferent signals from the gut to the brain. Microbial metabolites and host-derived neurotransmitters (e.g., serotonin, dopamine, GABA) influence mood, cognition, and stress responses. Enteroendocrine and enterochromaffin cells release neuroactive compounds in response to microbial cues.
🧬 2. Endocrine Pathway
The gut microbiota modulates HPA axis activity through changes in gut barrier integrity, circulating metabolites, and stress hormones. Cortisol, released from the adrenal cortex, affects both systemic inflammation and brain function. Microbiota-regulated hormones such as GLP-1, CCK, and ghrelin further influence appetite, mood, and behavior.
🦠 3. Immune Pathway
Microbial antigens (PAMPs) and metabolites interact with intestinal immune cells (e.g., Th1, Th17, dendritic cells), influencing systemic and neuroinflammatory tone. Elevated cytokines like TNF-α, IL-1, and IL-6 have been linked to blood-brain barrier disruption, depression, and cognitive impairment.
🔁 4. Metabolic Pathway
The gut microbiota ferments dietary components (e.g., fiber, protein, bile acids) into signaling molecules including:
-SCFAs (butyrate, propionate)
-Secondary bile acids
-Branched-chain amino acids (BCAAs)
These metabolites affect energy regulation, neurotransmission, and epigenetic signaling within the CNS and peripheral tissues.
A historical house in the heart of Isfahan, Iran 🇮🇷, dating back to the Safavid Empire (1501–1736 AD), now serving as a traditional Persian restaurant.
#archaeohistories