David Kuster

RNA & Metabolism. Ancient companions for Life. RNA as spatial organizer of the Cell. Phase separation, Aptamers & RNA fun @HymanLab. And birds @Birder_David.

[ShorterLab @ShorterLab]

Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration: https://t.co/X8O87v8VWT

[Kazuhiro Maeshima @kazu_maeshima]

Our linker histone H1 paper is featured on the cover of the April 10 issue of @ScienceAdvances.
https://t.co/fGZsmvRPWK
A molecular dynamics simulation of nucleosomes and linker histone H1, with single-H1 trajectories (background). 🎉 Full cover caption: https://t.co/Cj4Ey5RRfs

[David Morales-Álamo @D_Morales_Alamo]

New research shows “pearling” — a constriction of mitochondria — drives distribution of mitochondrial DNA nucleoids, helping ensure proper genetic organization and inheritance within cells. 🧬

https://t.co/Re7AKN8DZm

[Nature Chemical Biology @nchembio]

The Focus issue features views from redox biologists on the next frontiers and most needed developments in the field

https://t.co/VFQaeEnp6L

Free to read link: https://t.co/3H3TY3KFHX

[ShorterLab @ShorterLab]

A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms: https://t.co/0SQVxRQQyD

[Pombo-GarciaLab @karina_pombo]

We are hiring a research assistant for the lab! Come join us if you are excited about cell cell interactions in the gut, genetics and imaging! 
Deadline: 15 th March
Apply here 
https://t.co/iE2qyZeQLI

#oxford #Hiring #pombogarcialab

[Kazuhiro Maeshima @kazu_maeshima]

My student @Aoi_Otsuka_’s PhD work is now officially published @CSF_JSCB!
🔬Single-nucleosome imaging uncovers biphasic local chromatin dynamics in an oncogene-inducible human carcinogenesis model (1–3 d: same, 5–7 d: ↑, back by week 4). Congrats! 👏
https://t.co/2XjYoMj7gv

[Bede Portz @YSPTSPS]

https://t.co/cmGxbiO2gW

[News from Science @NewsfromScience]

The barrel-shaped structures found by the thousands in most animal cells are one of biology’s biggest mysteries. But although researchers haven’t figured out the function of these “vaults,” they now report a new use for the puzzling particles.

Learn more: https://t.co/nIPZxqSllp

[ShorterLab @ShorterLab]

Organelle biogenesis on a synthetic bead: https://t.co/jfuOmF8FEH

[Rothstein Lab @Rothstein_Lab]

TDP-43 dysfunction leads to the accumulation of cryptic transposable element-derived exons, crypTEs, in iPSC derived neurons and ALS/FTD patient tissues https://t.co/Mkjv0kWIC9

[Science Magazine @ScienceMagazine]

Cryogenic electron tomography of condensed chromatin enables multiscale analysis of its structure.

Learn more in a new #SciencePerspective: https://t.co/V80irgL5NW

[ShorterLab @ShorterLab]

Proximal proteomics reveals a landscape of human nuclear condensates: https://t.co/mgOmCQgxlx

[David Kuster @RNADavid]

@Absolutenivlek Not sure what to think of papers that fail to include Pinocytosis though...
@Absolutenivlek

[Ugo Kelvin Ihenacho @Absolutenivlek]

Pleased to announce that my PhD thesis work in @Blake_Hill_Lab on structural mechanisms governing vertebrate FIS1 function is finally out in JBC. https://t.co/iWp8RERYFu
🧵a thread

[Ugo Kelvin Ihenacho @Absolutenivlek]

🛡️”The Iron Dome”🛡️
Under alcohol stress, a slime mold rapidly retracts into a sclerotia of thousands of hexagonal spherules, sealing so tightly that Dextran-FITC (cyan) can’t enter.

Captured by me at the MBL Physiology Course (Gladfelter Lab rotation).

#MBL #Microscopy

[Ugo Kelvin Ihenacho @Absolutenivlek]

@RNADavid 👀

[David Kuster @RNADavid]

@Akruidhof00 This is AI generated, the depicted bird species does not exist.

[David Kuster @RNADavid]

@PierreHugot6 @Akruidhof00 Not at all, these are AI generated and the species doesn't exist in nature

[ShorterLab @ShorterLab]

Selective RNA sequestration in biomolecular condensates directs cell fate transitions: https://t.co/5BKEYHbWBv