📰 #InTheNews A new drug combination trialled at The Christie stops advanced lung cancer with EGFR mutations from progressing for longer than the drug that's currently in use.
More in the Guardian 👇 https://t.co/z0Jt5WAN1k
Great to rejoin the Manchester Immuno-Oncology Network #MION 🐝 at the first seminar of the 2024-2025 academic year.
Looking forward to many fruitful collaborations 🤝 between scientists & clinicians. @MCRCnews
Excellent talks from @IkShinChin1@giampazolias @JonathanWorboys!
Radiomics for early detection pneumonitis in PACIFIC: @DrJNaidoo
👉 x4 variables, inc clinical data
✅ Identifies symptomatic pneumonitis: PPV 0.46, NPV 0.93
🤔 Can it detect baseline asymptomatic ILD, to ⬇️ risk of future treatment associated pneumonitis?
#ESMO2024#LCSM
In this new review, Dr. @Roya_Behrouzi at @TheChristieNHS and team discuss how cell-free DNA profiling modalities can be harnessed to expand the clinical applications of liquid biopsy in small cell lung cancer.
https://t.co/7Pqtc78GBm
Please to share our work published in @iScience_CP comparing #cfDNA and small #extracellularvesicle DNA sequencing from the plasma of lung cancer patients. #liquidbiopsy
https://t.co/4onyatcQWQ [https://t.co/bm01wkHSr9]
Pleased to share our review published in @TrendsMolecMed on cell-free and extrachromosomal DNA profiling of small cell lung cancer
👉 https://t.co/wcDPvedcbe
Based on my MSc Precision Medicine research project supervised by Dr @FlorentMouliere at @cruk_nbc@CRUK_MI@UoM_DCS
Distinct clinical outcomes & biological features of
specific KRAS mutants in human pancreatic cancer
@Cancer_Cell
https://t.co/eZ0nLO7vWT
👉KRASG12R enriched in early stage w/ reduced nodal disease + distant recurrence
👉improved OS
🧐 Supports KRAS mutational testing in #PDAC
@my@myesmo
The Lung Team at the Christie is currently recruiting in studies for patients with stage 4 ROS1+ NSCLC who have received at least one previous line of treatment. If interested, please email [email protected]@BTOGORG@ros1cancer
HER2: a remarkable story of precision oncology.
Check this wonderful Nature review on targeting HER2 beyond breast.
👉Important to remember: now that we have an agnostic anti-HER2 drug approved (T-DXd), every adv cancer patient should get HER2 testing!
https://t.co/ptTRYd6aEF
Wow! GLP-1 receptor agonists now linked to a substantial reduction in incidence for 10 types of cancers, in patients with Type 2 Diabetes !https://t.co/xUiXl0wUAy
new @ScienceMagazine framework to improve cancer early detection:
two injectable priming agents (nanoparticles & engineered antibodies) temporarily slow down the clearance of circulating tumor DNA from the body, allowing for higher detection sensitivity
https://t.co/YDRYRk7L5a