Genome wide association studies have been used to identify genes that may be linked to opioid use disorder, but need hundreds of thousands of samples.
@MeWantData & collaborators have developed a way to identify these genes, using a small # of samples: https://t.co/EpidCNdIAV
Epigenetic convergence in opioid overdose. Great to see this multi-team collaboration in print! Such a great group of people on this project. S. Akbarian, D. Mash, E. Johnson, D. Hancock, @ScacheriLab@Bun_Without_B
https://t.co/1Esq61ykeR
@YinShenLab@xingjie_ren This is outstanding work! Amazing that an ave of 10 interval genes live between an enhancer and its target gene. How often do functional enhancers/promoters for a given MMR gene lie within the same TAD?
TWEETORIAL on our new #radonc paper in @TheLancetOncol -- joint work from @CCLRI@MoffittNews@CWRUSOM 1/n
Pan-cancer prediction of radiotherapy benefit using genomic-adjusted radiation dose (GARD): a cohort-based pooled analysis
https://t.co/3crLxn8VEP
@OncoAlert
Our studies are expanding from cancer into other major public health crises. Check out our latest on opioid use disorder. Team effort with Akbarian, Johnson, Mash, and @CorradinLab. https://t.co/bCGg8WOENB
Recruiting talented data scientists and molecular biologists to work on our newly funded project 👇🏼! This is our collective brainchild with @BullmanLab & @CJohnstonLab1.
Please retweet! Interested applicant please email [email protected] https://t.co/aZBeosg8fB
Evolutionary therapy is a new subfield in medicine (distinct from #evomed) that seeks to use our understanding of evolution to enable novel #cancer (& pathogen) therapy. Here we present the first link between #evotherapy and quantum physics. A #thread
https://t.co/8w3h3AliNh
How does resistance to targeted therapy develop in #lungcancer? Is it pre-existence or a de novo mechanism? @AndriyMarusyk lab @MoffittResearch adds evidence for a truly Darwinian, gradual development from tolerant persisters to full resistance. A THREAD https://t.co/r0hGbydoZu
Multiple sclerosis (MS) is considered an autoimmune disease. Researchers in the @CorradinLab led by @annAmbarbeau & the @TesarLab led by Daniel Factor found a role in MS for cells in the central nervous system—a potential new avenue for MS therapies: https://t.co/qVxzuT7jDD
Excellent preview in @Cancer_Cell covering recent work on the role of extrachromosomal circular DNA in cancer, including our study in @NatureGenet with @anton_gh et al. Thank you for the highlight, Chris Ott. https://t.co/KeKkRL35bn