Sumera Perveen, PhD

Scientist / Discoverer, University of Toronto @thesgconline

[Sumera Perveen, PhD @Sumera_Perveen]

@bookingcom Had worst experience with https://t.co/osa0QEyZdW can’t recommend it to anyone, n never going to use it again

[Sumera Perveen, PhD @Sumera_Perveen]

@bookingcom Yeah don’t pack because https://t.co/EUEX8GyUB6 cancel the booking last minute without notifying and dont resolve the issue. What legal action I can take as it caused inconvenience for the family with kids, have to stay on street with little kids in this scorching heat,

[Matthieu Schapira @mattschap]

All participants to CACHE challenges are invited to join the overview paper. https://t.co/mvPwayM8kD

CACHE#1 learnings:
-Workflows were diverse.
-Most top methods included some ML.
-Hits were weak: lots of room for improvement.
@thesgconline @consciencemeds #compchem

[Matthieu Schapira @mattschap]

Announcing CACHE2 results! Crowdsourcing and conventional methods did as well as novel ML. Teams started from 4 fragments in the PDB. We tested their predictions and found double-digit µM hits. This is the state-of-the-art. @thesgconline @consciencemeds https://t.co/Fbut1xK0yQ

[Sumera Perveen, PhD @Sumera_Perveen]

@joshdneufeld @ISME_microbes @OxUniPress @ISMEJournal Many congratulations, well deserved!

[JCIM & JCTC Journals @JCIM_JCTC]

Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2 #Docking
https://t.co/m4ggXNTpoq
@CherylArrowsmi1 @HalabelianLab @Sumera_Perveen @mattschap @thesgconline
#JCIM Vol64 Issue13 #Bioinformatics

[Matthieu Schapira @mattschap]

All participants to CACHE #1 who agreed to be de-anonymized were invited to join the overview manuscript. The first of a long series to serve as a resource for future developments in virtual screening workflows. https://t.co/ZArbyTvIgi @thesgconline @consciencemeds #compchem

[Sumera Perveen, PhD @Sumera_Perveen]

@ScienceMagazine 1 of my favourite pathway when I studied it first time during Grad school, Aerobic and aerobic hydrolysis of glucose. All the steps are still on my fingertips🙂

[Sumera Perveen, PhD @Sumera_Perveen]

CACHE symposium happening right now, alot of learning…

[Matthieu Schapira @mattschap]

Take home messages from D3R and ongoing SAMPL challenges outlined by Michael Gilson.

[aled edwards @aledmedwards]

Over the past 4 years, we applied machine learning to DEL screening data from 20 unprecedented targets. We found verified hits for half. Have a read!

[Sumera Perveen, PhD @Sumera_Perveen]

Read my latest #research on #HistonePosttransationalModifications, published with @wiley in @AdvancedScnce
https://t.co/EhWSfN5y5S

[Structural Genomics Consortium (SGC) @thesgconline]

A collaborative effort with @MSKCancerCenter has led to the development of a pair of complementary photo-arginine/δ-photo-lysine #probes to capture and explore the interactomes of Arg and Lys histone post-translational modifications.
Read more: https://t.co/fjmxh1lhab

[Sumera Perveen, PhD @Sumera_Perveen]

@alessiociulli @ThatsTVScotland @UoDCeTPD @CeMM_News @Nature Nice

[Communications Biology @CommsBio]

Structural and biophysical characterization of a small molecule binding to Cbl-b E3 ligase reveals an intermolecular glue mechanism locking the protein in an inactive state: https://t.co/e8q9SAA9kV

@HalabelianLab @thesgconline

[Sumera Perveen, PhD @Sumera_Perveen]

@SeanFraserMP Thank you

[Sumera Perveen, PhD @Sumera_Perveen]

@SeanFraserMP Thank you, Ramadan Mubarak to you too

[Dr. Omar Suleiman @omarsuleiman]

As Ramadan is near, I first and foremost seek anyone's forgiveness that I may have offended in person or online at any point. I pray Allah unites us all in that which is pleasing to Him.

To my brothers and sisters who share the noble vocation of Dawah with whom there may have been some disagreements, I'm sorry and pray we can work together for good.

To my brothers and sisters who I have caused injury to with a sermon or a word that may have been unintentional, I'm sorry and pray you will excuse me as I try to speak what is good.

To my brothers and sisters who have reached out to me via any personal communication and I was unable to respond, I'm sorry and I will try to do better inshaAllah.

To my brothers and sisters who may have approached me after an event and I was rushed and maybe seemed dismissive or tired, I'm sorry and pray we have long years in Jannah to catch up. Ameen

This life is too short to hold a grudge, or to let ego or envy take our eyes off the prize: A paradise bestowed upon us by our Lord in the company of the righteous. I pray we all make it there together. Ameen

Ramadan Mubarak to you all. May Allah accept your deeds in this month and beyond. Ameen

[Structural Genomics Consortium (SGC) @thesgconline]

Kicking off the SGC's 20th Anniversary Symposium with Dafydd Owen presenting the discovery and characterization of PAXLOVID, an orally bioavailable SARS-CoV-2 main protease inhibitor with in vitro pan-human coronavirus antiviral activity. #20yearsSGC

[Sumera Perveen, PhD @Sumera_Perveen]

@jaybradner I don’t let you leave

[Sumera Perveen, PhD @Sumera_Perveen]

@omarsuleiman504 Ameen

[Matthieu Schapira @mattschap]

Computational chemistry postdoc position open in my group at @thesgconline, University of Toronto, co-supervised by John Irwin @chem4biology at UCSF to enumerate and screen new areas of the chemical space: https://t.co/wnNE0SBpJu Please re-tweet!