Excited to share our work in @JCellBiol describing a new function for the E3 ubiquitin ligase RFWD3 (FANCW) in the regulation of replication fork remodeling. Terrific collaboration with Vincenzo Costanzo (temporarily twitterless) and @CicciaAlberto! (1/5) https://t.co/NDcIBZ8okz
We have open postdoctoral positions at Columbia University funded by our NIH T32 grant! If you are interested in studying genome or epigenome integrity, come and join us!
Congratulations to Tianpeng Zhang @zhtianp2 on his paper at Nature https://t.co/V2quWkhoq4 describing PCNA-Ub directed resection for template switch during Break Induced Replication at telomeres. Great collaboration with Patrick Sung and @YashpalRawal
Excited to share our recent work on KaryoCreate, a new method to engineer chromosome-specific gains and losses in human cells with @SteSantaguida and @GiuntaLab https://t.co/Eg7aEDAB7u Check out also recent similar and complementary work by @LensSusanne and @McClellandLab!
How do unique patterns of chromothripsis emerge in cancer and genomic disorders? Now out @Nature, we show that CIP2A-TOPBP1 tethers pulverized chromosomes from micronuclei, drives its asymmetric inheritance, and promotes a distinct rearrangement signature.
https://t.co/k0IGQZ5BCW
Excited to share our work in @JCellBiol describing a new function for the E3 ubiquitin ligase RFWD3 (FANCW) in the regulation of replication fork remodeling. Terrific collaboration with Vincenzo Costanzo (temporarily twitterless) and @CicciaAlberto! (1/5) https://t.co/NDcIBZ8okz