@abandopa@BSBEIITK1 Thanks so much Sir, for your kind words. I am always thankful for your support and teachings. Also, thankful to @BSBEIITK1 for nurturing me.
Thrilled to share first part of my post-doc work, published today in
@ScienceMagazine
https://t.co/U1ASlYuISY
We use reconstituted replication system and cryo-EM to unravel an unexpected mechanism of DNA translocation employed by eukaryotic replicative helicase.
Unlike the bacterial hexameric ring helicases that translocate in a sequential rotary hand-over-hand mechanism, we propose CMG translocates like a 'helical inchworm', oscillating between planar and spiral states.
My first post-doctoral project from RemusLab, MSKCC
Cryo-EM structures of G4-stalled CMG reveal inchworm mechanism of DNA translocation https://t.co/Kn9Qm5xf6m
Meet #MSKPostdoc Sahil Batra (@artablihas) from the Remus Lab. Sahil is a structural biologist studying the molecular mechanism of chromosomal DNA 🧬replication, focusing particularly on how the replication machinery deals with potential impediments in the DNA.
🇮🇳#NPAW2024
@BSBEIITK1@SankarIITK Congratulations @SankarIITK sir! Very well deserved. I will always remember how elegantly you taught Ramachandran map using dipeptide models.