Caitlin Guccione

PhD Graduate Student in Bioinformatics @UCSanDiego Working in the labs of @yosoykit and @KnightLabNews Cancer Microbiome • Bioinformatics • Math Modeling

[Kit Curtius @yosoykit]

Our work on filtering host DNA from WGS data now out in @NatureComms! Congrats to first authors @c_gucci3 and Lucas Patel @KnightLabNews - their methods are freely available to use on your own data 🧬
https://t.co/lzXB1QRw7a

[Kit Curtius @yosoykit]

How do microbial communities assemble during precancer & cancer evolution? Excited to share our new preprint on modeling of microbial evolution in Barrett's esophagus and esophageal adenocarcinoma! 🦠 Led by PhD student Caitlin Guccione https://t.co/dR0MJskJeK #barretts #mathonco

[Jens Luebeck @Jens_Luebeck]

📢📰 "Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma"

Congratulations to Owen Chapman, @SBPChavezLab, and Jill Mesirov's lab on their careful survey examining the clinical and cellular consequences of ecDNA.

https://t.co/WTJkSoRLRe

[Kit Curtius @yosoykit]

Our paper is out now in Bioinformatics! And check out the accompanying R package on CRAN to apply to your own single-cell data. Congrats @BrianJohnson_05 and Yubo Shuai! cloneRate: fast estimation of single-cell clonal dynamics using coalescent theory https://t.co/zHhawHYoyD

[Caitlin Guccione @c_gucci3]

Check out this awesome opportunity in my lab! @yosoykit and the rest of the QCC team have been great to work with.

[Kit Curtius @yosoykit]

Postdocs! Please apply to join our lab and work on mathematical/computational projects in cancer evolution and screening. Happy to discuss any details and tell you all about us 🤓 Please RT #mathonco

[Nature Microbiology @NatureMicrobiol]

You are what you excrete? 💩🧬 Is human DNA in faecal microbiome a problem?

The answer seems to be yes.

Read this News & Views to learn more, by @KnightLabNews and colleagues👇
https://t.co/Jk6Rr52sSn

[Kit Curtius @yosoykit]

Never have I been more proud of a title 😁 Check out our N&V out now in @NatureMicrobiol - led by PhD student @c_gucci3 with @KnightLabNews

[Kit Curtius @yosoykit]

Finally, Brian created a nice R package called cloneRate to recreate our results and to apply our methods to your own data. Check it out! https://t.co/6nmAh9W8NY 5/5 #mathonco #earlydetection

[Kit Curtius @yosoykit]

How fast does a clone grow? We used math and single cell-derived DNA sequencing data to find a simple solution – new preprint led by PhD student @BrianJohnson_05! Estimating single cell clonal dynamics in human blood using coalescent theory https://t.co/sc5jZFJKif 🧵👇 1/5

[Amelio Lab @AmelioLab]

Day 3 of #MoffittIMO and the competition is heating up! #TeamOrange 🍊subgroups showcase progress... what an amazing group of talented folks! @mathoncbro
@luddyka
@TuratiVirginia
@markrt_
@gustavl33024975
@jrm_black
@dbergman78
@helena_coggan
@S_Marzban
@c_gucci3

[Greg Sepich-Poore @multi_omics]

(1/5) Did you know that there are bacteria in human tumors? Well, this is old news now 😉. Our new study, in collaboration with @StraussmanR+@TPilpel+@KnightLabNews, is featured on the cover of @CellCellPress, showing that human tumors contain fungi too! https://t.co/YHkIOTRbRn

[Marco Mauri @MarcoMauri81]

Last talk at the "Mathematical modelling of microbiomes" in Plön @MPI_EvolBio by Caitlin Guccione "Evolutionary modeling of microbiome community assembly in the context of human pre-cancer progression" #MathModellingMicrobiomes

[cameron martino @cameronmartino]

Our review on the microbiome (bacteria, virus, archaea, and fungi) across life is out! Reviewing this broad topic put into perspective how much we know and how much more is waiting to be discovered. Thanks to @hazeldilmore (co-first) @Zach_Burcham @DirtySci @KnightLabNews

[Kit Curtius @yosoykit]

Happy 2 year anniversary to the QCC lab! 🥳 Thank you to our amazing trainees, collaborators, and my husband Ben for helping with the lifting of a fridge today 😂 best is yet to come! #mathonco

[Sandy Anderson @ara_anderson]

Having fun debating the importance of theory in cancer research with @Mdnicholson3 @DanielTemko @EvenMMyklebust @c_gucci3 @drjaydutt #CIRMcancer22

[Dani Perry @DPear_]

Such an exciting talk by @pratibhajagann_ at the @PacBio 2022 Discoveries Roadshow. What a star.

[Kit Curtius @yosoykit]

Very excited to share that I am a 2022 recipient of the AGA Research Scholar Award! Lots of work in IBD and mathematical modeling to come, in great AGA company. Special thanks to mentors @trevoragraham @samirguptaGI for all the support. #IBD #mathonco thank you @AmerGastroAssn

[cameron martino @cameronmartino]

Our paper on phylogenetic robust Aitchison PCA (RPCA) and compositional tensor factorization (CTF) is now available.

https://t.co/UnHoi2jEa9

Thanks to @KnightLabNews @mcdonadt @LiatShenhav @yoshikivb @gibsramen @LabAllaband @sejsong (and those not on Twitter)

[Kit Curtius @yosoykit]

It's #LynchSyndromeAwarenessDay! And our Review article is published online @APandT Lynch Syndrome-a mechanistic and clinical management update. I learned so much working w/ Dr. Rick Boland and @samirguptaGI - looking forward to more in this space for LS https://t.co/wsn60s3TJy

[cameron martino @cameronmartino]

Benchmarking of existing methods of filtering non-microbial sequences from WGS/shotgun data in both simulated and real data across sample types/extraction protocols. @mSystemsJ @KnightLabNews https://t.co/nEvdwWNKr2