Top Tweets for #mTORC
✅If the #Notch, b-catenin, #Wnt, #PI3K, #Akt, and #mTORC signaling pathways control #tumor #proliferation and differentiation in #osteosarcoma, which process could be defined as a priority #therapeutic target: tumor #proliferation/differentiation or #angiogenesis?
✅If spike-shaped #ECs determine the early development of #metastases and express #adhesion #molecules such as #MCAM, #CXCR4, #ANGPT2, and #KDR, could these molecules be used as #biomarkers for the #early #detection of metastases?
@ATHjournal @CardiologyPlus @atvbahajournals @CircRes @CircHF @CytoskelJournal @gkolost @HaoYin20 @IEEEembs @J_Cell_Sci @JCI_insight @JPBY_official @physiolrev @APSPhysiology @JPhysiol @Ahmed43101178 @drshafikuchay @RCMjournal @TrackYourHeart @JCVPOnline @CNIC_CARDIO @LuisSobrevia2 @CMPLPUCCHILE @FacMedicinaUC @Cancer_Cell @NatureRevCancer @CRC_AACR @RockUPress @WashUCardiology @WashUDeptMed @rust_ruslan @isth @The_MCSociety @cancerwarriors_ @ContraCancerEs 👇🧵👇
Research into tip-like endothelial cells (ECs) within #osteosarcoma is extremely rare.
The authors found that tip-like ECs were abundant in the primary tumors and metastatic foci.
🔓 Find out more in @Nature_NPJ: https://t.co/7HL66aaM1B
Happy to share with you my commentary in this week’s @Neurodiab_eu newsletter! #inflammatorypain #mTORC @ScienceAdvances
Unraveling new mediators of the mTORC1-dependent mechanical hypersensitivity in inflammatory pain
On Neurodiab website a signaling of articles on #diabeticneuropathy
The 96th NEUROdiab Publication News is by Ali Jaafar (https://t.co/NEB6Wd0uRk)
Arya Mani, MD, and Henry Ginsberg, MD, of @ColumbiaMed wrote about a fascinating study from the @AranyLab on alternative #mTORC pathway regulation of nonalcoholic fatty liver disease.
Read more in @ScienceMagazine: https://t.co/NxzG6EB4Ab
@YaleMed @YaleCVRC @YaleIMed
Thank you Arya Mani and Henry Ginsberg for nice editorial on our work unveiling work of alternative #mTORC pathway regulation of #NAFLD in @ScienceMagazine. https://t.co/ZHCBKGIOx2
Targeting PIKfyve to alleviate vascular neointimal hyperplasia after injury.
https://t.co/LmzLMy8h50
#vascular #restenosis #muscle #mTORC #silencing #phosphorylation #glucose #C57BL #carotid
Read this #preprint on @researchsquare: Lifespan of Catalase-Deficient Mice Decreases Due to Lysosomal Dysfunction https://t.co/eMRN3LlYGG
#peroxisome,#catalase, #ROS, #Aging,#lysosomes, #mTORC
#TTI1 variants (member of TTT complex) affect #mTORC signalling, cell-cycle progression and/or DNA damage response and repair causing an autosomal recessive developmental disorder with #microcephaly
Margaux Serey-Gaut #ESHG2021
#mTORC Glucagon Resistance and Decreased Susceptibility to #Diabetes in a Model of Chronic Hyperglucagonemia @DRI @umiamimedicine
https://t.co/5BYPB1Gc6m
🔔New issue online!
Articles on:
*⃣ SNARE complex assembly
*⃣ #Structuralbiology
*⃣ #TCellReceptorsignaling
*⃣ #Mitochondrial oxidants in #BarthSyndrome
*⃣ #Gquadruplex RNA, #TDP43
*⃣ #Circadian changes in Rheb, #mTORC, and #mitochondria
& more ➡ https://t.co/SnDUyHLNqm
The #kinase SGK1 acts as a signaling hub downstream of #BMP9/#ALK1 to control #proteinsynthesis and proliferation in #endothelial cells →https://t.co/vIDF3KGW3f #angiogenesis #cellsignaling #mTORC
New twists on heterogeneity of extracellular vesicles by @GoberdhanLab: reduced #glutamine or #mTORC signaling induces tumorigenic Rab11-positive #exosomes with altered cargo
https://t.co/cofgP0GxI7
Tomorrow at @AgingSciTalks please join us at 1pm EST for @RobertoZoncu presenting on “Molecular mechanisms of lysosomal mTORC1 signaling”! https://t.co/tXWIo6ASMq
#AKT signaling is required in vivo for #BAT development but dispensable for #skeletalmuscle development.
#adipose #WAT #adipogenesisi #insulin #mTORC #obesity #lipodystrophy
https://t.co/9E7tXoXyB7
It is possible that #sarcoidosis could be treated with #mTORC inhibitors? Maybe in the future...ThomasWeichart told us #ATS2018 #ILD @FibrosisPulmon @ILDunit_clinic
mTORC1 signaling just got more complicated: mEAK-7 recruits mTOR to the lysosome to activate S6K2 https://t.co/LwUMzevJeS @ScienceAdvances #mTORC #cellbiology
Researchers have identified a key nutrient sensor in the mTOR pathway that links nutrient availability to cell growth. https://t.co/DR9lDKxfED
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