Andy McPartlin

Radiation Oncologist @pmcancercentre

[Andy McPartlin @ajmcpartlin]

@Adam_Weiner535 @NEJM @ASCO @PCF_Science 5r mfs early to understand benefits. ~20% disease free at 4 yr -3% difference between arms. BF rate not given but most pts will presumably be considered for sRT with longer fu. Is non-select trimodality therapy for a disease where DE RT gives excellent LC a step forward.

[Andy McPartlin @ajmcpartlin]

@VickersBiostats @ahmederaky No post sx lymphoedema in 1500 patients is unusual. Post RT tox data would be informative as a fu if available. There’s a lack of high level data in this space, thanks for publishing.

[Andy McPartlin @ajmcpartlin]

@VickersBiostats @ahmederaky Interesting idea. Major side effect patients would worry about is chronic significant lymphedema of the lower limb. Risk raised ++ by extended PLND and salvage RT. What value vs single met cured by sbrt. Conclusion seems overstated. Need trial ideally.

[Claire Rooney @RadOncRooney]

Delighted to publish our work with @ajmcpartlin and the @pmcancercentre @UHN_Otohns @UofTDRO team on impact of PORT neck volumes on salivary fn in OSCC

-27% hyposalivation post-op
-⬆️RT neck volume predicts salvia fn recovery & chronic hyposalivation

https://t.co/FS7xmnmQZ3

[ASTRO @ASTRO_org]

New in the #RedJournal: Phase 2 single-arm trial of SBRT for patients with oligoprogressive breast, genitourinary and gastrointestinal cancers: by 1 yr, ~1/2 of patients could maintain their current line of systemic therapy and ~1/3 had no progression. https://t.co/6mQNYriE3K

[Andy McPartlin @ajmcpartlin]

@jaydetsky @ASTRO_org @SahgalArjun @Sunnybrook @UofTDRO Congrats Jay- great work!

[Andy McPartlin @ajmcpartlin]

@CJTsaiMDPhD @imrtlee @MSK_RadOnc @MSKCancerCenter Kudos the the team. Great study, fantastic for patients. Question how much this is due to intrinsic hypoxia/radio sensitivity vs interaction with immune response. Awaiting the HPV -ve data 🍿

[Andy McPartlin @ajmcpartlin]

@simona_gaito @OfficialUoM @TheChristieNHS @RRR_UoM @marianneaznar @edsmith_mcr @FBMH_DocAcad Congrats Simona, fantastic effort to complete this through Covid era- real achievement!

[Andy McPartlin @ajmcpartlin]

@Lisa56495402 @swinton_martin Great presentation @swinton_martin!!

[Andy McPartlin @ajmcpartlin]

@JamesBatesMD @ESTRO_RT 🙏

[Andy McPartlin @ajmcpartlin]

@DavidSherMD Love the concept. GTV-CTV-PTV accounts for various uncertainties (clinician/imaging/ planning/set up etc) that vary between cases and centres. TROG 0202 LRC lower at smaller centers. Tighter margins may accentuate this. RTQA crucial.

[Andy McPartlin @ajmcpartlin]

@ezrahahn @CJTsaiMDPhD @Dr_AliHosni @ScottBratman Agreed. The primary site outcome is fascinating too in comparison to E3311. Lots to think about.

[Andy McPartlin @ajmcpartlin]

@ProtonStorey @5_utr @gminniti2012

[Andy McPartlin @ajmcpartlin]

@DavidSherMD @JoaquinJCabrera Had a demo yesterday- lots of possibilities!

[Andy McPartlin @ajmcpartlin]

@simona_gaito @royalmarsdenNHS @ALESSIOBRUNI10 @gminniti2012 @marianneaznar @edsmith_mcr Excellent news, congratulations!!

[Andy McPartlin @ajmcpartlin]

@MCRCnews @marianneaznar @OfficialUoM @RT_physics @UoM_DCS @finn_corinne @Al_McWilliam @FBMH_UoM @KathrynBanfill @AngieDavey_ @achoud72 Congratulations!! Truly well deserved.

[Andy McPartlin @ajmcpartlin]

@PKyzas Congrats Panos- well deserved!

[Andy McPartlin @ajmcpartlin]

Dose to inferior brain stem is associated with dysphagia at one year following RT for HNSCC.

Great work by @elivaos @AzadehAbravan and @DebGandertonSLT, true multidisciplinary project!

https://t.co/WX5JMhrStY

[Andy McPartlin @ajmcpartlin]

@DrDThomson @CRUKresearch @RTTQA_UK Congratulations! Fantastic effort