Our paper on cell type-specific changes in dup15q syndrome during development and in the adult human brain is out in NatureComms: https://t.co/MgPh1pZPPR. Thanks to the co-first author Yonatan Perez, @Kriegsteinlab and all authors. Special thanks to donors and @AutismBrainNet!
For #RareDiseaseDay we're returning to a BNAdv article on information processing in a mouse model of Ehmt1 haploinsufficiency, which is associated with rare neurodevelopmental conditions such as Kleefstra syndrome. Authors @bribrdav @ProfAntIsles et al https://t.co/9WkV3A0GOP
Transparent peer review for all!
We will publish reviewer reports and author responses for all research articles submitted after November 1st
#OpenScience
https://t.co/9wOOv3U6y1
Kicking off Pitt Hopkins Awareness Month with all the latest #PittHopkins news packed into one place -- check out our latest newsletter here ⬇
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This is the first time logging into "X". My "Twitter" publicity game is dwindling into nothing. But, I do want to say I am proud that we contributed to the latest work from Brittany Davis in the Maher lab showing synaptic dysfunction after TCF4 loss.
@KordingLab Also photo bleaching will be an issue. So might have to threshold each cell so depolarization is at similar magnitude/tuned to particular cell and use individual holographic imagining to reduce light exposure. But probably will want both optical and electrical control.
@KordingLab Optical? Temporal dynamics aren’t great. Even if we have opsin fast enough to stimulate neurons at a similar frequency as electrical stimulation (maybe?) do we have microscopes that can capture necessary frame rate across entire brain? (these are genuine questions)
@Oliver__Hahn@CellCellPress@wysscoray Wow, super interesting! And hopeful, even? A continuously dividing population of cells--lots of potential for anti-aging therapeutics! Congrats!
https://t.co/y2P3b4vVPB
Our paper is out! We found that a transcription factor #TCF4 is a part of human neural #development, and it regulates (RIMBP2) which is disrupted in #autism spectrum disorders (#ASD)! It's free access this month!
#research#neuroscience#plasticity
@Primalprimate And not to be too pedantic. But these regions 'light up' for most socio-emotional processing, this does not mean we're constantly experience disgust. Also by 'light up' you mean an fMRI study? Which famously look at changes in blood flow and not circuitry dynamics/activity?
@kaymtye lists—though you can obviously reference in answering the prompts. It seems to be an effort to de-emphasize the prestige of labs/pubs/funding etc, while offering room to expound on career breaks, science comm., training others, and good science citizenship!