Laura Prendergast

HHMI/NYU Postdoc in @ReinbergDanny’s lab. PhD in Cancer Biology. Interests include: chromatin biology, replication stress, genome stability, and linker histones

[Laura Prendergast @LauraPrenderg14]

It's about time we started talking about the forgotten H1 linker histone variants. Check out our review in @GenesDev for a discussion of emerging trends for H1 variant-specific functions. @ReinbergDanny @CSHL #chromatin #transcription #nucleosome
https://t.co/W6HCrpRbDm

[Antoine van Oijen 🔬🧫🧬 @van__Oijen]

Remember that intro biology class where you learned about helicases using ATP to unwind DNA during replication?

We figured out that that might not be the case...

@uowresearch @MolHorizons @ihmri

https://t.co/gfVzkkYjFe

[Ariel Kaplan @akaplanz]

Finally! our paper on the structure and dynamics of linker histones is officially published:
https://t.co/zZPN0k22Sg
Congrats @nucleosomezky and all the authors, and thanks to @LabPMelamed for a great collaboration!

[Sergei Rudnizky @nucleosomezky]

Excited to share our work on #chromatosome now published in @MolecularCell. I had fun unzipping chromatosomes to learn how they work :). Congrats! @Hadeel_Khamis8, Yuval, Efrat, @LabPMelamed @akaplanz

https://t.co/EUGUYKSyiH

[Jen Heemstra @jenheemstra]

Publishing papers is great, but they don't determine your value.

Getting grants can be important, but they don't set your self-worth.

Receiving awards is fun, but they don't replace family and friends.

It's okay to enjoy academic achievements, but remember we are people first.

[Sanxiong.liu @LiuSanxiong]

Our latest work is on @biorxivpreprint, https://t.co/jpiG9RuxH1. We reported Polycomb activates gene expression in the brain, and patients with AUTS2 mutations phenocopy mutations in CBP/P300 and share features with Rubinstein-Taybi syndrome. Huge thanks to my co-authors.

[Bing-Rui Zhou @zhoubr]

Added to my Saturday reading list, a timely review of the functions of histone H1 variants in chromatin by @LauraPrenderg14 and @ReinbergDanny

[Bing-Rui Zhou @zhoubr]

#chromatin folks, excited to share our recent study on the structures and dynamics of chromatosomes with different human linker histone H1 isoforms. A collaboration with CMM @NCIResearchCtr and Anna Panchenko @queensu, now online in @MolecularCell. https://t.co/5U8sPAv229

[Jia-Ray Yu @JiaRayYu1]

Our recent work uncovering the H3K36me2 writer-reader module as a epigenetic vulnerability in H3K27M-DIPG

Thanks all!
@ReinbergDanny @GaryLeRoy3 @placantonakilab @stairway_2devin @rs_meyer @NDescostes

The H3K36me2 writer-reader dependency in H3K27M-DIPG https://t.co/HSlhTJZyEK

[Laura Prendergast @LauraPrenderg14]

@Kavoshex Thank you Amin! I hope all is well with you!

[Laura Prendergast @LauraPrenderg14]

It's about time we started talking about the forgotten H1 linker histone variants. Check out our review in @GenesDev for a discussion of emerging trends for H1 variant-specific functions. @ReinbergDanny @CSHL #chromatin #transcription #nucleosome
https://t.co/W6HCrpRbDm

[Genes & Development @GenesDev]

January issue of @GenesDev is online! @judd_julius @susan_gasser @columbiacancer @UCSanDiego @TheCrick @CRUK_BI @UofGCancerSci @DrPhil_94 @BoultonLab @METorresPadilla @ClaraHermant @LauraPrenderg14 @ReinbergDanny @MarkusHafner4 @CincyChildrens @RogerJDavis1

[Genes & Development @GenesDev]

In this review, Prendergast and Reinberg discuss the likelihood that the family of histone H1 variants may be key to understanding several fundamental processes in chromatin biology. @LauraPrenderg14 @ReinbergDanny
https://t.co/j4RON3ytaZ

[Robert Schneider @robert_ife]

You always wanted to know what this puzzling linker histone H1 subtypes are doing 🧐? Very nice and comprehensive review by @ReinbergDanny in @GenesDev
https://t.co/4jid4iqe4z

[Peter Lewis @thePeterLewis]

comprehensive review on histone H1 variants from @LauraPrenderg14 @ReinbergDanny

https://t.co/OENEUlhNUz

[Ankita Saha Ph.D @Ankita_Saha_H1]

My graduate work from the late Dr. Mizzen's lab is now published in a special issue by IJMS!
'Site-Specific Phosphorylation of Histone H1.4 Is Associated with Transcription Activation'
https://t.co/fXMC4zAWT6 via @MDPIOpenAccess

[Inna Smalley 🇺🇦 @InnaSmalley]

To anchor a figure in text so it never moves and you can stop raging at your computer this grant season:

Paste figure-> Right click, Wrap text, select “Tight” then “More layout options”, go to position tab-> Unclick "move object with text", click "lock anchor"
#ScienceTwitter

[Laura Prendergast @LauraPrenderg14]

My review w/ @ReinbergDanny on the emerging trends & variant-specific functions of somatic H1 linker histones (H1x, H1.0 & H1.1-H1.5) was just accepted to @GenesDev! Stay tuned! @CSHL #chromatin #transcription #histone #chromatosome #epigenetics #nucleosome

[Nucleosome papers 📚 NucPosDB database @Nucleosome_Bot]

FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner https://t.co/TzC8xxQBTP

[Laura Prendergast @LauraPrenderg14]

Great review published earlier this year highlighting the mysteries of the chromatosome. It is astonishing how little we understand about this fundamental repeating unit of chromatin! https://t.co/L5qViQT7AD